2 6 Diacetylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2,6-diacetylpyridine

    Specifications

    HS Code

    896062

    Chemical Formula C7H7NO2
    Molar Mass 137.14 g/mol
    Appearance Yellow to brown solid
    Odor Characteristic
    Melting Point 93 - 95 °C
    Boiling Point 271 - 272 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in ethanol, chloroform, etc.
    Density 1.167 g/cm³
    Flash Point 131.9 °C

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    General Information
    Where to Buy 2,6-diacetylpyridine in China?
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    Frequently Asked Questions

    As a leading 2,6-diacetylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-diacetylpyridine?
    2% 2C6-diethylaniline has a wide range of main uses. In the dye industry, it is often a key raw material for the manufacture of a variety of dyes. If you want to make azo dyes with bright color and good fastness, 2% 2C6-diethylaniline is indispensable. Due to its special structure, it can participate in many chemical reactions. By ingeniously combining with other compounds, it gives the dye its unique color and properties.
    In the field of medicine, this compound also has its own uses. It can be used as an intermediate in the synthesis of certain drugs. Due to its specific chemical activity and structural characteristics, it can provide the necessary structural units for the construction of drug molecules, and help to develop drugs with specific pharmacological activities to deal with various diseases.
    In addition, in the field of organic synthesis, 2% 2C6-diethylaniline is often used as an important reagent. With its active chemical properties, it can participate in many organic reactions, such as nucleophilic substitution, addition and other reactions, which help to synthesize complex organic compounds and contribute to the development of organic synthetic chemistry. Its importance in the chemical industry is like tenon and mortise in construction. Without it, many links are difficult to proceed smoothly, which is an important substance to promote the development of related fields.
    What are the physical properties of 2,6-diacetylpyridine?
    2% 2C6-diethylaniline is an organic compound with unique physical properties. Looking at its properties, it is usually a colorless to light yellow oily liquid with a special smell.
    When it comes to boiling point, it is about 216-218 ° C. This boiling point characteristic is of great significance in separation and purification operations such as distillation. At this temperature, 2% 2C6-diethylaniline can be converted from liquid to gaseous state, so that it can be separated from other substances with different boiling points.
    In terms of melting point, it is about -50 ° C. The lower melting point indicates that it usually exists in liquid form at room temperature. Only when the temperature is greatly reduced to -50 ° C will it solidify into a solid state.
    Its density is about 0.93g/cm ³. This density data makes it exhibit a specific state when mixed with other liquids such as water. Because its density is less than that of water, it will float on the water surface when mixed with water.
    Solubility is also an important physical property. 2% 2C6-diethylaniline is insoluble in water, but soluble in organic solvents such as ethanol and ether. This solubility characteristic is widely used in the field of organic synthesis and analytical chemistry. For example, in some organic reactions, its solubility in organic solvents can be used to select a suitable organic solvent as the reaction medium to promote the smooth progress of the reaction. At the same time, in the process of material separation, it can be effectively separated from other substances according to their solubility differences.
    In addition, 2% 2C6-diethylaniline is volatile to a certain extent and will evaporate slowly in the air. During use and storage, it is necessary to pay attention to its volatility and take appropriate measures to avoid losses due to volatilization or safety problems.
    What are the chemical properties of 2,6-diacetylpyridine?
    2% 2C6 -diisopropylaniline, which is an organic compound. The chemical properties of this substance are quite important and are described by you today.
    First, it is basic. Because the nitrogen atom in the amino group has an unshared electron pair and can accept protons, it can form salts in acidic media. In case of strong acid, the amino nitrogen atom can combine with the proton to form a corresponding ammonium salt. This property makes it useful in organic synthesis as a base to neutralize acids or participate in specific acid-base reactions.
    Second, the activity of aromatic electrophilic substitution. The benzene ring is connected with an amino group and an isopropyl group, and the amino group is the power supply group, which can increase the electron cloud density of the benzene ring and make the benzene ring more vulnerable to electrophilic reagents. Common reactions such as halogenation reactions, under appropriate conditions, halogens such as chlorine and bromine can replace hydrogen atoms on the benzene ring; in nitration reactions, nitro groups can also be introduced into the benzene ring; sulfonation reactions can also occur, and sulfonic acid groups will be connected to the benzene ring. And such reactions mainly occur in the o and para-positions of amino groups. Due to the effect of amino groups, the electron cloud density of the o and para-positions is relatively higher.
    Third, the reaction of alkyl groups. As an alkyl group, isopropyl groups have certain stability, but reactions can occur under special conditions. For example, at high temperature or with a suitable catalyst, the carbon-hydrogen bond on the isopropyl group can be oxidized to form the corresponding oxygenated compounds such as alcohols, alters or carboxylic acids; reactions such as carbon-carbon bond cleavage may also occur, but such reactions usually require more harsh conditions.
    Fourth, it can participate in the condensation reaction. Amino groups can condensate with compounds containing functional groups such as carbonyl groups. If reacted with alaldehyde or ketone, imines can be formed, which is an important method for constructing carbon-nitrogen double bonds in organic synthesis. The resulting imines can further participate in many reactions to prepare more complex organic compounds.
    In conclusion, 2% 2C6 -diisopropylaniline is rich in chemical properties and has important uses in organic synthesis, medicinal chemistry and other fields.
    What are the synthesis methods of 2,6-diacetylpyridine?
    The synthesis methods of 2% 2C6-diisopropyl aniline are as follows:
    First, the reaction of alkylation is carried out with aniline and isopropyl alcohol as the starting material under the condition of catalyst existence. Among them, the catalysts involved are often acidic catalysts, such as activated clay and molecular sieves. The mechanism of the reaction is that isopropyl alcohol is dehydrated to propylene under the action of the catalyst, and then propylene and aniline undergo electrophilic substitution reaction to generate 2% 2C6-diisopropyl aniline. The advantage of this approach is that the raw materials are easy to obtain and the reaction conditions are relatively mild. However, the selectivity of the product may be insufficient, and there may be many side reactions.
    Second, 2-isopropylaniline is used as the raw material, and then the isopropylation reaction is carried out. This process also requires the help of catalysts, and Lewis acid catalysts can be selected, such as aluminum trichloride. During the reaction, 2-isopropylaniline interacts with isopropylation reagents (such as isopropylhalide, etc.) to generate the target product 2% 2C6-diisopropylaniline in a specific reaction environment. The advantage of this method is that the purity of the product may be higher, but the cost of the raw material 2-isopropylaniline may be higher, and the isopropylation reagents used may be toxic and corrosive, which requires stricter reaction equipment and operation.
    Third, using nitrobenzene as the starting material, 2% 2C6-diisopropyl nitrobenzene is obtained by isopropylation reaction, and then the nitro group is reduced to an amino group to obtain 2% 2C6-diisopropyl aniline. In the isopropylation stage, suitable catalysts and reaction conditions need to be selected to ensure the smooth introduction of isopropyl into the specific position of the benzene ring. The reduction of nitro groups can be achieved by catalytic hydrogenation, using precious metals or skeleton nickel as catalysts, or chemical reduction methods, such as iron powder, zinc powder, etc. as reducing agents. The advantage of this route is that the cost of raw material nitrobenzene is low, and the selectivity of the product can be improved by controlling the reaction conditions. However, there are many reaction steps and the process is slightly complicated.
    What are the precautions for using 2,6-diacetylpyridine?
    2% 2C6-diethylaniline, when used, should not be ignored.
    First, this substance is toxic and harmful to humans. If the skin is absorbed, inhaled or eaten, it can cause poisoning. If it is eaten, it is especially harmful, or it is damaged. Therefore, when operating, it is necessary to wear protective clothing, such as protective clothing, gloves, gas masks, etc., to prevent contact.
    Second, 2% 2C6-diethylaniline is flammable and explosive. In case of open flame or high temperature, there is a danger of explosion. Store it in a good place, and store it in parts such as oxidation and acid to avoid damage to the environment.
    Third, this chemical product is also harmful to the environment. During use, do not let it flow into the environment. If there is a leak, immediate emergency measures should be taken to prevent pollution from spreading. A small amount of leakage can be adsorbed by sand, dry lime, etc.; a large amount of leakage should be contained in the embankment and then treated.
    Fourth, use 2% 2C6-diethylaniline, and the operator should be familiar with its properties, hazards and emergency management methods. The operation should follow the procedures, and the operation steps should not be changed deliberately.
    Therefore, the use of 2% 2C6-diethylaniline is based on safety and weight, and comprehensive consideration of various factors, so as to avoid the problem.