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What is the chemical structure of 2,6-bis ((S) -4-methyl-4,5-dihydrooxazol-2-yl) pyridine
This is the chemical structure analysis of 2,6-bis ((S) -4-methyl-4,5-dihydrooxazole-2-yl) pyridine. This compound contains a pyridine ring connected with (S) -4-methyl-4,5-dihydrooxazole-2-yl at the 2nd and 6th positions, respectively.
The pyridine ring is a six-membered nitrogen-containing heterocycle with aromatic properties and stable structure. In this compound, the pyridine ring plays a core skeleton role. And (S) -4 -methyl-4,5 -dihydrooxazole-2 -group, containing oxazole ring structure, this ring is a five-membered heterocycle with oxygen and nitrogen heteroatoms in the ring. The existence of methyl groups at the 4 position introduces steric hindrance and electronic effects to the oxazole ring. And the 4 and 5 positions of the oxazole ring are dihydro states, indicating that the double bond position is different from that of the ordinary oxazole ring, which has a great influence on the electron cloud distribution and reactivity.
(S) configuration indicates that this group has chirality, and the chiral characteristics are of great significance in the field of drug and asymmetric synthesis. Different configurations may have different biological activities and interactions with receptors. The overall structural properties of this compound determine its unique properties and potential applications in organic synthesis, catalytic reactions, materials science, drug development and other fields. The delicate design and unique properties of its structure may provide opportunities and possibilities for new reaction exploration, new material creation and new drug development.
What are the main uses of 2,6-bis ((S) -4-methyl-4,5-dihydrooxazol-2-yl) pyridine
2%2C6-bis%28%28S%29-4-methyl-4%2C5-dihydrooxazol-2-yl%29pyridine, this is one of the organic compounds. Its main uses are quite extensive.
In the field of organic synthesis, it is often used as a ligand. Due to its special structure, it can coordinate with a variety of metal ions to form metal complexes. These metal complexes exhibit excellent performance in catalytic reactions. For example, in some asymmetric catalytic reactions, it can effectively improve the selectivity and activity of the reaction, helping chemists to accurately synthesize organic compounds of specific configurations, which is of great significance in drug synthesis, materials science and many other fields.
In the field of materials science, it also has important applications. With the help of coordination with metal ions, metal-organic framework materials (MOFs) with unique structures and properties can be constructed. Such materials exhibit excellent properties in gas adsorption and separation, catalysis, and fluorescence sensing. For example, in the field of gas adsorption, it can exhibit a high degree of adsorption selectivity for specific gases, which can be used to efficiently separate target gases from mixed gases.
In the field of medicinal chemistry, its structure contains a specific heterocyclic structure or has a certain biological activity. Scientists can modify and optimize the structure of this compound to develop new drug molecules. It may participate in the regulation of specific biochemical processes in organisms, opening up new avenues for drug development.
To sum up, 2%2C6-bis%28%28S%29-4-methyl-4%2C5-dihydrooxazol-2-yl%29pyridine in many key fields such as organic synthesis, materials science, medicinal chemistry, etc., all play an indispensable role and make great contributions to the development of related fields.
What are the synthesis methods of 2,6-bis ((S) -4-methyl-4,5-dihydrooxazol-2-yl) pyridine
The method of synthesizing 2,6-bis ((S) -4-methyl-4,5-dihydrooxazole-2-yl) pyridine has been explored by chemists throughout the ages, and the common methods mentioned above are one or two.
First, start with pyridine-2,6-dicarboxylic acid, and first heat with thionyl chloride to convert the carboxyl group to acid chloride. This step needs to be in a well-ventilated environment and carefully control the temperature to prevent the escape of acid chloride. The obtained acid chloride is then combined with (S) -4-methyl-4,5-dihydrooxazole-2-amine in a suitable solvent, such as dichloromethane, and reacted at low temperature with an organic base, such as triethylamine, as an acid binding agent. Low temperature can reduce side reactions, but it is necessary to pay attention to the reaction process at all times and adjust the temperature in a timely manner. After the reaction is completed, the product can be obtained by extraction and column chromatography.
Second, with 2,6-dibromopyridine as the starting material, the Grignard reagent is first prepared with magnesium chips in anhydrous ether. This process needs to ensure that the system is anhydrous and oxygen-free, otherwise the Grignard reagent is easy to decompose. The prepared Grignard reagent is then reacted with (S) -4-methyl-4,5-dihydrooxazole-2-formaldehyde, and the reaction is completed. After the reaction is completed, it is treated with dilute acid to protonate the generated alcohol hydroxyl group and dehydrate it to form the target product. After distillation, recrystallization and other methods are purified.
These two methods have advantages and disadvantages. The former reaction conditions are relatively mild, but the steps are slightly complicated; although the latter steps are slightly simpler, the preparation of Grignard reagent requires strict requirements. The synthesis method needs to be weighed against many factors such as the ease of availability of raw materials, cost considerations, and high and low yield before the optimal method can be found.
What are the physical properties of 2,6-bis ((S) -4-methyl-4,5-dihydrooxazol-2-yl) pyridine
2% 2C6 - bis% 28% 28S% 29 - 4 - methyl - 4% 2C5 - dihydrooxazol - 2 - yl% 29pyridine, is an organic compound. Its physical properties are quite investigated.
Looking at its morphology, under normal temperature and pressure, it is mostly in the shape of a solid state. Due to the intermolecular force, the structure tends to stabilize, causing it to maintain a solid phase in common environments. And the color of this compound is usually white or almost white powder, with a pure appearance. < Br >
When it comes to melting point, due to specific molecular structures and interactions, the melting point is in a specific range, about [X] ° C. This temperature characteristic is crucial for material identification and purity determination.
Its solubility also has characteristics. In organic solvents such as dichloromethane and chloroform, it exhibits good solubility. This is because the solvent and solute molecules can form suitable interactions, such as van der Waals force, hydrogen bond, etc., to help the molecules disperse uniformly. However, the solubility in water is poor, because the polarity of the compound molecules is quite different from that of water, it is difficult to form effective interactions.
Furthermore, the density of this compound is also an important physical property. According to its molecular composition and packing method, the density is about [X] g/cm ³. This value reflects the relationship between its mass and volume, and has reference value in many practical application scenarios.
Its stability is relatively impressive under common conditions, and the chemical bonds in the molecular structure give it a certain ability to resist external interference. In case of extreme conditions, such as high temperature, strong acid and alkali environment, the structure may change and the stability will be damaged.
In summary, the physical properties of 2% 2C6 - bis% 28% 28S% 29 - 4 - methyl - 4% 2C5 - dihydrooxazol - 2 - yl% 29pyridine, such as morphology, color, melting point, solubility, density and stability, have their own characteristics and are of great significance in the fields of organic synthesis and materials science.
What is the market outlook for 2,6-bis ((S) -4-methyl-4,5-dihydrooxazol-2-yl) pyridine
There are currently 2,6-bis ((S) -4-methyl-4,5-dihydrooxazole-2-yl) pyridine, an organic compound. Its market prospects are quite promising.
In the chemical industry, this compound is often a key intermediate for synthesis. Due to its special molecular structure, it has excellent reactivity and selectivity, and can assist in the synthesis of many complex and special organic materials. In the development and preparation of new polymer materials, it may provide unique structural units for polymerization reactions, endowing materials with specific properties such as better mechanical properties and thermal stability. Therefore, in the frontier research of materials science, it is often regarded as a promising basic raw material, and the demand for it in the chemical industry may be gradually increasing.
In the field of medicine, because of its structure and bioactive molecules, it can be used to design and synthesize new drugs. Researchers hope that by modifying and modifying its structure, they can develop high-efficiency and low-toxicity drugs for specific disease targets. For example, the development of anti-tumor and antiviral drugs has its own applications. With the continuous progress of pharmaceutical science and technology, the demand for compounds with unique structures and activities is increasing, and this compound may occupy an increasingly important position in the pharmaceutical R & D industry chain, and the market prospect is quite bright.
Furthermore, in the field of catalysis, 2,6-bis ((S) -4-methyl-4,5-dihydrooxazole-2-yl) pyridine can be used as a ligand to form an efficient catalyst for coordinating with metal ions. Such catalysts exhibit excellent catalytic performance in many organic reactions, can improve reaction rates, optimize reaction yields, and have good stereoselectivity. With the deepening of the concept of green chemistry, the demand for efficient and environmentally friendly catalysts has increased sharply, and the catalysts derived from this compound are expected to be widely used in industrial catalytic processes, with huge market potential.
In summary, 2,6-bis ((S) -4-methyl-4,5-dihydrooxazole-2-yl) pyridine has broad market prospects in chemical industry, medicine, catalysis and other fields. Over time, it will be able to shine in related industries and promote the development and progress of the industry.