2,6-bis((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine

2%2C6-bis%28%28R%29-4-isopropyl-4%2C5-dihydrooxazol-2-yl%29pyridine, this is an organic compound. Its main application field is quite wide, and it has a unique effect in the field of catalysis.
In asymmetric catalytic reactions, the compound often acts as a ligand. Due to its special structure, it can be closely combined with metal catalysts to build an efficient and highly selective catalytic system. This system exhibits excellent performance in many organic synthesis reactions, such as hydrogenation reactions and allylation reactions. It can precisely control the reaction stereochemistry to generate products of specific configurations, greatly improve the reaction efficiency and product purity, and is of great significance in the fields of drug synthesis and total synthesis of natural products.
In the field of materials science, it also has applications. With its unique coordination ability and structural properties, it can be used to prepare functional materials. For example, complex materials with special optical and electrical properties are formed by assembling with metal ions, which may have potential applications in luminescent materials, sensor materials, etc., and open up new ideas for the research and development of new functional materials.
In the frontier fields of chemical research, scientists continue to explore its new applications. For example, in emerging organic synthesis strategies, supramolecular chemistry, etc., they are trying to tap more potential properties and application values to promote the continuous development of chemical science.

To prepare 2,6-bis ((R) -4-isopropyl-4,5-dihydrooxazole-2-yl) pyridine, there are several common methods.
One is to use pyridine as the starting material, introduce a suitable functional group at the 2,6-position of pyridine, and then convert it into an oxazole structure through a series of reactions. First, pyridine interacts with a specific halogenated reagent, introducing a halogen atom at the 2,6-position to form 2,6-dihalopyridine. Subsequently, the dihalopyridine undergoes a nucleophilic substitution reaction with a nucleophilic reagent containing (R) -4 -isopropyl-4,5 -dihydrooxazole-2 -yl. The preparation of the nucleophilic reagent is quite critical, which can be obtained from the corresponding chiral alcohol through multi-step reaction, so that the chiral alcohol is condensed with a suitable nitrogen-containing compound to construct an oxazole ring, and then isopropyl is introduced, and the final nucleophilic reagent is reacted with 2,6 -dihalopyridine to obtain the target product.
In the second method, the (R) -4-isopropyl-4,5-dihydrooxazole-2-based structure on one side can be constructed first, and then connected to the pyridine derivative. For example, (R) -4-isopropyl-4,5-dihydrooxazole-2-yl-halogen is prepared from suitable chiral raw materials, and then with pyridine-2,6-diborate or similar reactive pyridine derivatives, under the action of suitable catalysts, through coupling reaction. Commonly used catalysts such as palladium catalysts, in the presence of bases, promote the coupling of the two to obtain 2,6-bis ((R) -4-isopropyl-4,5-dihydrooxazole-2-yl) pyridine.
There are also those prepared by the strategy of intramolecular cyclization. Design a suitable long chain precursor, which contains a pyridine fragment and the group required to construct an oxazole ring. Under suitable reaction conditions, the long chain molecule first undergoes intramolecular reaction to construct an oxazole ring, and at the same time is connected to pyridine to form the target product. This process requires precise control of reaction conditions, such as temperature, solvent, catalyst, etc., to ensure the smooth progress of the cyclization reaction and the maintenance of the configuration of the chiral center. Each method has its own advantages and disadvantages, and it needs to be selected according to the actual situation, such as the availability of raw materials, the ease of control of reaction conditions, and the requirements of product purity.

2%2C6-bis%28%28R%29-4-isopropyl-4%2C5-dihydrooxazol-2-yl%29pyridine is an organic compound, which is very important in the field of chemistry. Its physical and chemical properties are unique, and in-depth investigation of it is of great significance for understanding the relevant chemical reactions and material properties.
Looking at its physical properties, under normal conditions, the compound may be a solid with a specific melting point and boiling point. The level of melting point depends on the strength of the intermolecular force. If the intermolecular force is strong, such as the existence of hydrogen bonds, van der Waals forces, etc., the melting point is relatively high; vice versa. The same is true for the boiling point, which is related to the intermolecular force and molecular mass. Generally speaking, the larger the molecular mass, the stronger the intermolecular force and the higher the boiling point. Its color may be colorless to slightly yellow, and this color characteristic may be related to the electron transition in the molecular structure.
As for chemical properties, the presence of the pyridine ring and the dihydrooxazole group in this compound endows it with unique reactivity. The pyridine ring is aromatic and has a special electron cloud distribution, which can participate in electrophilic substitution reactions. Under appropriate conditions, electrophilic reagents can attack specific positions on the pyridine ring to generate new derivatives. The nitrogen and oxygen atoms in the dihydrooxazole group contain lone pairs of electrons, which can be used as ligands to coordinate with metal ions to form metal complexes. This coordination is widely used in catalytic reactions, materials science and other fields. For example, some metal complexes can be used as catalysts to accelerate the process of specific chemical reactions and improve reaction efficiency and selectivity. And the compound may have a certain acidity and alkalinity, because the pyridine ring nitrogen atom can accept the proton alkalinity, while some hydrogen atoms of the dihydrooxazole group can be dissociated under specific conditions, showing acidity. This acidity and alkalinity has a great impact on its stability and reactivity under different chemical environments.

I don't know what you said about the market price of 2,6-bis ((R) -4-isopropyl-4,5-dihydrooxazole-2-yl) pyridine. However, if you want to know its price, you can follow various paths.
First, visit the chemical raw material trading platform. Such platforms gather many suppliers, list the prices of various chemicals, or get their price ranges. Second, consult chemical product distributors. They are often involved in the trading of a variety of chemicals, and are quite familiar with market prices, or can tell you their approximate prices. Third, participate in industry exhibitions. Here, you can face manufacturers and suppliers directly. In addition to asking the price, you can also know the product characteristics and market conditions.
However, its price is not constant and often fluctuates due to many factors. If the cost of raw materials, if the price of raw materials for the production of this compound is high, the price of the finished product may also rise; if the market supply and demand exceed the supply, the price may rise; if the supply exceeds the demand, the price may fall. And different purity and packaging specifications, the price is also different. The price of high purity is higher, and the unit price may be different for large packages compared to small packages. Therefore, in order to know the exact price range, it is necessary to explore in detail through the above channels.

2% 2C6 - bis% 28% 28R% 29 - 4 - isopropyl - 4% 2C5 - dihydrooxazol - 2 - yl% 29pyridine, that is, 2,6 - bis (R) - 4 - isopropyl - 4,5 - dihydrooxazole - 2 - yl) pyridine, the manufacturer of this product, many skilled craftsmen in the world, but there are also several good at this industry.
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