2,6-Bis[(4S)-4-phenyl-2-oxazolinyl]pyridine

2% 2C6 - Bis% 5B% 284S% 29 - 4 - phenyl - 2 - oxazolinyl%5Dpyridine, which is the English name of an organic compound. In the ancient classical text of "Tiangong Kaiwu", the chemical structure of this compound is described as follows:
Look at this compound, which is based on pyridine, and its binary and hexadecimal positions, each connected to a specific group. This group has a chiral oxazoline structure and is connected to a phenyl group at the quaternary position of oxazoline. In the oxazoline structure, nitrogen and oxygen form a five-membered heterocycle with the carbon atom in a specific bonding manner. Among them, the chiral center is located at the carbon atom of the quaternary position of oxazoline, which is in the (4S) configuration. The conjugated structure of the pyridine ring imparts certain stability and electronic properties to the whole compound. The oxazoline group connected increases the complexity of its steric hindrance and electronic effects due to the presence of the benzene ring. The structure of the whole molecule, the atoms are connected to each other by covalent bonds, forming a specific three-dimensional spatial arrangement. Such a unique chemical structure makes it have special physical and chemical properties, and may have extraordinary functions in many fields such as organic synthesis and catalysis.

2% 2C6 - Bis% 5B% 284S% 29 - 4 - phenyl - 2 - oxazolinyl%5Dpyridine, the Chinese name is often called 2,6 - bis [ (4S) - 4 - phenyl - 2 - oxazolinyl] pyridine. This substance has important applications in many fields.
In the field of catalysis, it can act as a chiral ligand. Chiral ligands are crucial in asymmetric catalytic reactions and can induce reactions to selectively generate products of a specific configuration. Taking asymmetric hydrogenation as an example, this ligand combined with a metal catalyst can realize asymmetric hydrogenation of compounds containing unsaturated bonds such as carbon-carbon double bonds and carbon-oxygen double bonds, and generate products such as chiral alcohols and chiral amines with high optical purity, which is of great significance in the pharmaceutical industry. The synthesis of many chiral drugs relies on such asymmetric catalytic reactions to obtain a single configuration of active ingredients.
In the field of materials science, this compound can be used to prepare materials with special optical and electrical properties. Due to the specific functional groups and chiral centers in the molecular structure, it can endow materials with unique properties. For example, in the preparation of chiral luminescent materials, its luminescence properties can be adjusted to achieve circularly polarized luminescence, which shows potential application value in frontier fields such as 3D display and optical storage.
In the field of supramolecular chemistry, it can self-assemble with other molecules or ions to form supramolecular systems with specific structures and functions by virtue of intermolecular interactions, such as hydrogen bonding, π-π stacking, etc. These supramolecular systems can be used for molecular recognition, substance separation, etc. For example, the identification and inclusion of specific structure guest molecules can achieve efficient separation and purification of target substances in complex mixtures.

To prepare 2,6-bis [ (4S) -4-phenyl-2-oxazolinyl] pyridine, there are various methods. Pyridine is often used as a group, and suitable groups are introduced at its 2,6 positions first, and then cyclized to construct oxazoline rings.
If 2,6-pyridinedicarboxylic acid is used as the starting point, it is first condensed with suitable amines to obtain amides, and then dehydrated and cyclized to form this compound. This process requires fine temperature control, selection of suitable reagents and solvents. In the reaction, temperature affects the cyclization rate and product purity, and the purity and activity of reagents are related to the reaction process. < Br >
Or start with pyridine and halogenated aromatic hydrocarbons, couple through metal catalysis, and then introduce nitrogen-containing heterocyclic precursors, and then cyclize to form the target. The activity and selectivity of the metal catalyst are the key, and the ligand also affects the reaction.
In addition, the final product can be obtained by modifying and linking from the precursor with oxazoline ring and reacting with pyridine derivatives. This approach requires the selection of the linking reaction to ensure the selectivity and high efficiency of the reaction check point.
During the synthesis, each step of the reaction needs to be carefully monitored and optimized, and the progress and purity need to be monitored by means of thin layer chromatography and nuclear magnetic resonance. Purification steps are also important, and high purity products are often obtained by column chromatography, recrystallization and other methods. Each method has its own advantages and disadvantages, and the best path is selected according to actual needs and conditions to achieve the purpose of high-efficiency and high-purity synthesis.

2% 2C6 - Bis% 5B% 284S% 29 - 4 - phenyl - 2 - oxazolinyl%5Dpyridine is an organic compound with unique physical properties. Its appearance is often white to light yellow crystalline powder, which is easy to store and handle, and has good stability in most environments. It is not prone to spontaneous chemical changes.
The melting point of this compound is quite important, usually in a specific temperature range. Determination of the melting point can help to identify its purity and characteristics. Due to the fixed melting point of pure compounds, the melting point will change if it contains impurities.
In terms of solubility, it has a certain solubility in common organic solvents such as dichloromethane and chloroform. This property makes it well dispersed in organic synthesis reactions, providing a homogeneous environment for the reaction, which is conducive to full contact of reactant molecules and promotes the reaction. However, its solubility in water is low, because it contains more hydrophobic groups, and the force between it and water molecules is weak.
In addition, it also has certain thermal stability. In a specific temperature range, its structure and properties do not change significantly with temperature increase, which is of great significance in high temperature reactions or processing processes. It can ensure that it maintains structural integrity and chemical activity under corresponding conditions, thereby ensuring the smooth development of related reactions or applications.

2% 2C6 - Bis% 5B% 284S% 29 - 4 - phenyl - 2 - oxazolinyl%5Dpyridine, Chinese name or 2,6 - bis [ (4S) -4 - phenyl - 2 - oxazolinyl] pyridine. This compound is widely used in the field of materials science and organic synthesis. In materials science, it is often used as a ligand to complex with metal ions to prepare high-performance materials, such as luminescent materials, catalytic materials, etc. Due to its unique structure, it can endow materials with special optical and electrical properties, and has broad prospects in optoelectronic devices, sensor manufacturing, etc.
In the field of organic synthesis, it is a key chiral ligand. It is used for asymmetric catalytic reactions, which can improve the enantioselectivity of the reaction and efficiently synthesize chiral compounds. Chiral compounds are indispensable in the fields of medicine, pesticides, etc., so their demand is very high.
In terms of market prospects, with the progress of science and technology, the development of optoelectronic devices, sensors and pharmaceutical industries is rapid, and the demand for them continues to grow. The development of materials science has given rise to R & D requests for new high-performance materials. As an important ligand raw material, the dosage of this compound will increase. The demand for chiral compounds in the research and development of new drugs in the pharmaceutical field is increasing. As chiral ligands, the market potential is huge.
However, its market also The market competition is fierce, it is necessary to improve synthesis technology, reduce costs and enhance competitiveness. Environmental protection requirements are becoming stricter, and the production process needs to pay attention to green chemistry and reduce environmental impact in order to adapt to market development.