2,6-bis[(4R)-4,5-dihydro-4-methyl-2-oxazolyl]-Pyridine

2% 2C6 - bis% 5B% 284R% 29 - 4% 2C5 - dihydro - 4 - methyl - 2 - oxazolyl% 5D - Pyridine, Chinese name or 2,6 - bis [ (4R) -4,5 - dihydro - 4 - methyl - 2 - oxazolyl] pyridine. This substance is widely used in the field of organic synthesis.
First, in the field of catalysis, it is often used as a ligand. It can complex with metal ions to form a catalyst with unique properties. Due to its specific spatial structure and electronic effect, it can significantly improve the activity and selectivity of catalytic reactions. For example, in some asymmetric synthesis reactions, metal catalysts using this compound as a ligand can precisely control the three-dimensional configuration of the reaction products and produce high-purity single chiral compounds, which is of great significance in fields such as drug synthesis that require strict optical purity.
Second, in materials science, it is also used as a building unit. By chemical reaction, it is introduced into the structure of polymer materials, which can endow the material with special properties. Because of its nitrogen-containing heterocyclic structure, it can enhance the thermal stability, mechanical properties and adsorption properties of specific substances, etc., it is a promising basic raw material in the preparation of high-performance functional materials.
Third, in the field of medicinal chemistry, the structure of this compound may be used as a lead structure. After structural modification and optimization, drug molecules with specific biological activities are developed. Its unique molecular skeleton may interact with specific targets in vivo, exhibiting biological activities such as antibacterial, anti-inflammatory, and anti-tumor, providing an important structural template for the development of innovative drugs.

The methods for the synthesis of 2,6-bis [ (4R) -4,5-dihydro-4-methyl-2-oxazolyl] -pyridine have many paths. The common ones are based on suitable pyridine derivatives, so that it can be condensed with oxazole derivatives with specific configurations under suitable reaction conditions. In this process, the selection of appropriate solvents, catalysts, temperature, time and other conditions is of paramount importance.
If the parent pyridine is prepared first, it is chemically modified to make its activity check point suitable for binding to the oxazole part. Oxazole derivatives need to be carefully prepared according to the (4R) configuration to ensure their optical purity. Then, in an inert gas-protected environment, organic solvents such as dichloromethane and toluene are selected, dissolved in them, and suitable alkali catalysts, such as triethylamine and pyridine, are added to promote the reaction. Control the reaction temperature in a moderate range, or at room temperature to tens of degrees Celsius, and after several hours or even days of reaction, the two can be fully condensed.
Another method is to construct the oxazole ring part first, and then gradually connect it to the pyridine skeleton. That is, oxazole compounds containing specific substituents are first synthesized, and after a series of operations such as protection and activation, they are connected to the pyridine derivatives by coupling reaction. In this coupling reaction, palladium-catalyzed cross-coupling reactions can be selected to precisely control the reaction check point and product structure.
Furthermore, or by means of biosynthesis, specific enzymes or microbial systems can be used to catalyze the synthesis of this compound. However, this method requires in-depth understanding and regulation of the biological system to ensure that the reaction occurs according to the expected path, and the product is easy to separate and purify.
All synthesis methods have advantages and disadvantages, and need to be carefully selected according to specific needs, raw material availability, cost considerations and other factors.

2%2C6-bis%5B%284R%29-4%2C5-dihydro-4-methyl-2-oxazolyl%5D - Pyridine, this substance has specific physical and chemical properties. It may be a solid at room temperature, because the molecule contains multiple cyclic structures and heteroatoms, and the intermolecular force causes it to have a higher melting point and boiling point.
From the perspective of solubility, because it contains polar oxazolyl and pyridine rings, it has a certain solubility in polar organic solvents such as ethanol and acetone, and can interact with solvent molecules to form hydrogen bonds. However, in non-polar solvents such as n-hexane, the solubility is low. Due to the large difference in polarity, it does not conform to the principle of "similar compatibility".
The substance is basic, and the nitrogen atom of the pyridine ring has lone pairs of electrons, which can accept protons. In chemical reactions, oxazolyl and pyridine rings are active check points. The chiral center (4R configuration) of oxazole ring endows it with chiral characteristics and has potential applications in the field of asymmetric synthesis. It can be used as a chiral ligand or catalyst to induce reactions to form products of specific configurations.
Its stability is high, and the cyclic structure and conjugate system reduce the molecular energy. However, under extreme conditions such as strong acid, strong base or high temperature, chemical bonds may be affected to react, such as ring opening and substitution. Due to its structural characteristics and potential activity, it may have important uses in pharmaceutical chemistry, materials science and other fields. It can be used as a lead compound for drug research and development or for the preparation of functional materials with special properties.

There is a question today, what is the price of 2,6-bis [ (4R) -4,5-dihydro-4-methyl-2-oxazolyl] -pyridine in the market. However, I have not been involved in the transaction of this industry, and it is difficult to know the current market conditions, so it is difficult to determine its price.
In the market, the price varies with factors such as supply and demand, current conditions, and materials. Or at a certain time, the price of this product is high due to the large number of people who need it; or due to the large number of producers and oversupply, the price falls.
If you want to know the exact price, do not consult a chemical material firm, a chemical trading market, or an online chemical trading platform, where there may be quotations for this product for reference. Or ask someone who specializes in chemical trading, who has been involved in this for a long time and is familiar with the market, and should be able to tell the exact price.

The current name of the substance is 2,6-bis [ (4R) -4,5-dihydro-4-methyl-2-oxazolyl] -pyridine. To know its safety and toxicity. Although the relevant information of this substance is not widely disseminated in the market, it is also a point of concern in the academic community and chemical research institutes.
In terms of its safety, under normal use and storage conditions, if there is no improper operation and environmental changes, it can generally maintain a relatively stable state. However, under the interaction of different media, different temperature and humidity and other conditions, this substance may have subtle changes, so it needs to be treated with caution. In a specific environment, the influence of various factors should be carefully investigated to ensure its safety.
As for toxicity, after past research, its effect on organisms is complex. Under small doses, or only cause some subtle physiological changes in organisms, but the dose increases gradually, or it may affect the cell metabolism and physiological function of organisms. And the target organs and target cells of its effect also vary depending on biological species and individual differences. In animal experiments, it can be seen that some of the tested animals have pathological changes, such as abnormal liver and kidney function indicators.
In summary, although there is a certain understanding of the safety and toxicity of this substance, more detailed studies are needed to clarify its exact impact on life and the environment in various situations. When using it, strict procedures should be followed to prevent unexpected disasters.