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What is the chemical structure of 2,6-Bis [ (3aS, 8aR) -3a, 8a-dihydro-8H-indeno [1,2-d] oxazolin-2-yl] pyridine?
2% 2C6 - Bis%5B%283aS%2C8aR%29 - 3a% 2C8a - dihydro - 8H - indeno% 5B1% 2C2 - d% 5Doxazolin - 2 - yl% 5Dpyridine, this is the name of an organic compound. Looking at its name, we can summarize its chemical structure.
"2,6 - Bis" means the 2nd and 6th positions of the pyridine ring, each with the same substituent. This substituent is "% 5B% 283aS% 2C8aR% 29 - 3a% 2C8a - dihydro - 8H - indeno% 5B1% 2C2 - d% 5Doxazolin - 2 - yl% 5D" structure.
"% 283aS% 2C8aR% 29" This is a chiral identifier, indicating the three-dimensional configuration of the 3a and 8a positions in the structure. "3a, 8a-dihydro-8H-indeno" indicates that this is a derivative of dihydroindene, "% 5B1% 2C2-d% 5Doxazolin-2-yl" is shown in the 1,2-position of the indene ring and the upper oxazoline ring, and the second position of the oxazoline ring is connected to the pyridine ring.
In summary, the structure of the compound is a substituent containing the dihydroindoxazoline structure with a specific chiral configuration at the 2,6 positions of the pyridine ring. The uniqueness of its structure may endow the compound with specific physical, chemical and biological activities, which may be of great significance in the fields of organic synthesis and medicinal chemistry.
What are the main uses of 2,6-Bis [ (3aS, 8aR) -3a, 8a-dihydro-8H-indeno [1,2-d] oxazolin-2-yl] pyridine?
2% 2C6 - Bis%5B%283aS%2C8aR%29 - 3a% 2C8a - dihydro - 8H - indeno% 5B1% 2C2 - d% 5Doxazolin - 2 - yl% 5Dpyridine, an organic compound with a wide range of main uses. In the field of organic synthesis, it is often used as a ligand. Ligands can combine with metal ions to form metal complexes, which can play a key role in catalytic reactions.
In asymmetric catalytic reactions, its effectiveness is particularly significant. Asymmetric catalysis aims to selectively generate products with specific configurations. The metal complexes formed by this compound can efficiently and selectively catalyze the reaction, promoting the reaction to proceed in the desired stereochemical direction, so as to obtain a high-purity single configuration product. In many drug synthesis, the product configuration requirements are strict, and this compound can play a role in the synthesis of pharmaceutical ingredients with specific biological activities.
In addition, in the field of materials science, it also has potential uses. Or it can participate in the construction of materials with special structures and properties, and with its unique molecular structure, give the material different characteristics, such as affecting the optical and electrical properties of the material. Overall, this compound holds important application value in organic synthesis and materials science, providing powerful tools and approaches for the development of related fields.
What are the synthesis methods of 2,6-Bis [ (3aS, 8aR) -3a, 8a-dihydro-8H-indeno [1,2-d] oxazolin-2-yl] pyridine?
There are several common methods for the synthesis of 2,6-bis [ (3aS, 8aR) -3a, 8a-dihydro-8H-indo [1,2-d] oxazoline-2-yl] pyridine.
First, using pyridine as the starting material, through a specific substitution reaction, a suitable functional group is introduced, and then the oxazoline ring is constructed by cyclization reaction. In this process, the reaction conditions and reagents need to be carefully selected. If you want to replace it, you can use a halogenated reagent to replace the hydrogen atom on the pyridine ring with a halogen atom at an appropriate temperature and solvent. Then, compounds containing nitrogen and oxygen are used to form oxazoline structures through condensation and cyclization steps. This step requires precise regulation of reaction pH, temperature and other conditions to ensure that the reaction proceeds in the desired direction and improves the yield of the target product.
Second, indanoxazoline derivatives can also be used as starters and are connected to pyridine through a coupling reaction. In this path, it is crucial to choose an efficient coupling catalyst. For example, the coupling reaction catalyzed by transition metals, palladium, nickel and other metal catalysts can promote the formation of carbon-carbon or carbon-heteroatomic bonds. When reacting, it is necessary to pay attention to the activity of the substrate, the amount of catalyst and the reaction time, and strive to obtain the ideal synthesis effect.
Third, part of the structure can be constructed first, and then the target product can be obtained by stepwise splicing and modification. For example, the intermediate containing oxazoline fragment is first synthesized, and then the two oxazoline fragments are effectively connected to pyridine by functional group transformation and ligation reaction. This strategy requires precise control of the selectivity and yield of each step of the reaction. During the synthesis and modification of the intermediate, the reaction parameters are finely adjusted to make the reaction proceed smoothly and achieve the synthesis of 2,6-bis [ (3aS, 8aR) -3a, 8a-dihydro-8H-indo [1,2-d] oxazoline-2-yl] pyridine.
What are the physical properties of 2,6-Bis [ (3aS, 8aR) -3a, 8a-dihydro-8H-indeno [1,2-d] oxazolin-2-yl] pyridine?
2% 2C6 - Bis%5B%283aS%2C8aR%29 - 3a% 2C8a - dihydro - 8H - indeno% 5B1% 2C2 - d% 5Doxazolin - 2 - yl% 5Dpyridine is an organic compound. The physical properties of this compound are quite important, and it is related to its performance in various chemical processes and practical applications.
Its properties may be crystalline and have a specific crystal structure. This structure can be seen in a regular arrangement under a microscope, caused by intermolecular forces. The morphology and color of crystals may vary depending on purity and preparation conditions.
Melting point is one of the key physical properties. After accurate determination, its melting point falls in a specific temperature range. At this temperature, the molecule can break through the lattice binding and change from solid to liquid. Melting point can not only be used to identify the purity of compounds, but also is of great significance to the study of their stability in high temperature environments.
Solubility cannot be ignored. In common organic solvents, such as ethanol and dichloromethane, the degree of solubility varies. Good solubility or makes the compound easy to participate in the homogeneous reaction, while insolubility may affect the reaction process, or special reaction conditions or co-solvents are required to promote the reaction.
In addition, the density of the compound is also characterized by physical properties. Density reflects the mass per unit volume, which is indispensable for the calculation of its concentration in solution and the study of related mixing systems. < Br >
Furthermore, its refractive index also has specific values. Refractive index can assist in determining the purity and concentration of compounds, and is widely used in optical materials and related analytical techniques.
The various physical properties of this compound are interrelated, which jointly affect its chemical behavior and practical uses, and are of important guiding value for chemical research and industrial applications.
What is the market price for 2,6-Bis [ (3aS, 8aR) -3a, 8a-dihydro-8H-indeno [1,2-d] oxazolin-2-yl] pyridine?
Today's question, what is the market price of 2,6-bis [ (3aS, 8aR) -3a, 8a-dihydro-8H-indo [1,2-d] oxazoline-2-yl] pyridine? This is involved in the field of fine chemicals, but its market price is difficult to determine.
The price of this compound is determined by many factors. First, the difficulty of its preparation is the key. If the preparation method is cumbersome, requires multiple steps of reaction, and the yield of each step is not high, or requires rare raw materials, harsh reaction conditions, such as specific catalysts, high temperature and high pressure, etc., the cost will increase, and the price will also increase.
Second, the situation of market supply and demand also affects its price. If the compound has a large demand in the fields of medicine and materials, but the supply is limited, the supply is in short supply, the price will rise; conversely, if the demand is small and the supply is large, the price will decline.
Third, the price varies between manufacturers and brands. Well-known large factories, due to their emphasis on quality and strict production management, their product prices may be higher than those of small factories.
As far as I know, on the market, the price of this compound may vary depending on the purity and packaging specifications. For ordinary purity, the price per gram may be in the hundreds of yuan; for high purity, for scientific research precision experiments, the price per gram can reach thousands of yuan. However, this is only a rough estimate. To know the exact price, you must consult chemical raw material suppliers, reagent sellers, etc. to know the accurate market value in the near future.
