2 6 Bis 2 Benzimidazol 2 Yl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2,6-Bis(2-benzimidazol-2-yl)pyridine

    Specifications

    HS Code

    766520

    Chemical Formula C22H14N6
    Molar Mass 362.39 g/mol
    Appearance Solid
    Melting Point N/A (decomposes)
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO
    Color Light - colored (usually white to off - white)
    Odor Odorless
    Uv Vis Absorption Absorbs in the UV region
    Fluorescent Property Exhibits fluorescence under certain conditions

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    General Information
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    Frequently Asked Questions

    As a leading 2,6-Bis(2-benzimidazol-2-yl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2,6-Bis (2-benzimidazol-2-yl) pyridine?
    2% 2C6 - Bis% 282 - benzimidazol - 2 - yl% 29pyridine, in terms of the ancient classical text of Tiangong Kaiwu, this is a compound. Its chemical structure is centered on the pyridine ring, and there are two 2-benzimidazolyl groups connected to the 2 and 6 positions of the pyridine ring.
    Looking at the pyridine ring, this is a six-membered nitrogen-containing heterocycle with unique electron cloud distribution and chemical activity. The benzimidazolyl group is fused from the benzene ring and the imidazole ring, which also gives the compound special properties. This structure makes the compound have excellent coordination ability and can form complexes with various metal ions. The nitrogen atom on the benzimidazolyl and pyridine ring can provide lone pairs of electrons to coordinate with metal ions to form a stable structure.
    Furthermore, this structure may make it exhibit special properties in the fields of optics and electricity. The conjugation system of benzimidazolyl and pyridine ring may affect its electron transition behavior, so that the compound may have specific fluorescence emission and light absorption characteristics. The unique chemical structure of this compound lays the foundation for its application in many fields such as materials science, chemical synthesis and coordination chemistry, and shows broad research and application prospects.
    What are the main application fields of 2,6-Bis (2-benzimidazol-2-yl) pyridine
    2% 2C6 - Bis% 282 - benzimidazol - 2 - yl% 29pyridine, which is 2,6 - bis (2 - benzimidazolyl) pyridine, is widely used and has its own impact in many fields.
    In the field of material chemistry, it is often used as a ligand. Due to its unique structure, it can coordinate with a variety of metal ions to form metal complexes with different properties. These complexes have significant applications in luminescent materials and can be prepared with specific luminescent properties, such as for organic Light Emitting Diodes (OLEDs), which can improve the luminous efficiency of the device and precisely control the luminous color, contributing to the development of display technology.
    In the field of catalysis, the metal complexes formed by 2,6-bis (2-benzimidazolyl) pyridine are often used as catalysts. In some organic synthesis reactions, it exhibits high catalytic activity and selectivity. For example, in the carbon-carbon bond formation reaction, it can effectively reduce the reaction conditions, improve the reaction yield, promote the progress of organic synthesis chemistry, and provide an efficient way for the synthesis of new compounds.
    In the field of biomedicine, it also has potential applications. Some studies have shown that metal complexes containing this ligand have inhibitory effects on certain cancer cells, and are expected to be developed as new anti-cancer drugs. At the same time, due to its coordination characteristics with metal ions, it can be used to design biosensors to achieve highly sensitive detection of specific metal ions in living organisms, and to assist biomedical research and disease diagnosis.
    In summary, 2,6-bis (2-benzimidazolyl) pyridine plays a key role in materials, catalysis and biomedicine, and its application prospects will be broader with the deepening of research.
    What are the synthesis methods of 2,6-Bis (2-benzimidazol-2-yl) pyridine
    2% 2C6 - Bis% 282 - benzimidazol - 2 - yl% 29pyridine is 2,6 - bis (2 - benzimidazolyl) pyridine. The synthesis method is as follows:
    To prepare 2,6 - bis (2 - benzimidazolyl) pyridine, the common method is to use pyridine - 2,6 - dicarboxylic acid and phthalediamine as raw materials. First, mix pyridine - 2,6 - dicarboxylic acid and phthalediamine in an appropriate proportion, and add an appropriate amount of solvent, such as polyphosphoric acid, etc. This solvent is not only the reaction medium, but also can promote the reaction. Heat up to a certain temperature, usually at a higher temperature, such as 180-220 ° C, for several hours. During this process, the carboxyl group of pyridine-2,6-dicarboxylic acid and the amino group of phthaleamine undergo a condensation reaction to gradually form the structure of the target product. After the reaction is completed, the reaction system is cooled, and it is poured into an appropriate amount of water to precipitate out. After suction filtration, washing, drying, etc., the crude product can be obtained. Then recrystallization with an appropriate solvent, such as ethanol, DMF, etc., is further purified to obtain a pure 2,6-bis (2-benzimidazolyl) pyridine. < Br >
    There are also 2- (2-bromophenyl) -1H-benzo [d] imidazole and 2- (pyridine-2,6-diyl) diborate as raw materials, prepared by palladium-catalyzed coupling reaction. First, the two are placed in suitable organic solvents, such as toluene, dioxane, etc. with palladium catalysts, such as tetra (triphenylphosphine) palladium, ligands, bases, etc. Under the protection of inert gas, heated to a suitable temperature, such as 80-110 ° C, and reacted for a period of time. After the reaction is completed, the target product can be obtained by extraction, column chromatography and other separation methods. This method has relatively mild conditions and good selectivity, but the cost of raw materials and catalysts is higher.
    What are the physical properties of 2,6-Bis (2-benzimidazol-2-yl) pyridine
    2% 2C6 - Bis% 282 - benzimidazol - 2 - yl% 29pyridine, that is, 2,6 - bis (2 - benzimidazolyl) pyridine, this is an organic compound. Its physical properties are unique, let me tell you one by one.
    Looking at its morphology, under normal temperature and pressure, it is often in a solid state, which is stable because of its strong intermolecular force, resulting in an orderly arrangement of molecules. And its melting point is quite high, requiring a higher temperature to melt it into a liquid state. This property is of great significance in many application scenarios, such as in chemical reactions in high temperature environments or material preparation, its structural stability can ensure that the reaction proceeds as expected.
    When it comes to solubility, the compound exhibits a certain solubility in organic solvents. For example, in common polar organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it can be better dissolved. However, in water, the solubility is poor. This difference in solubility is due to its molecular structure. The benzimidazolyl and pyridyl groups in the molecule give it a certain hydrophobicity, so the hydrophilicity is weaker than that of organic solvents.
    Furthermore, it has good thermal stability. During heating, the molecular structure remains stable at higher temperatures, and little decomposition or deterioration occurs. This property makes it suitable for the synthesis and processing of materials in high-temperature processes, and can impart excellent thermal properties to the materials.
    Its crystallization properties are also worth mentioning. Under appropriate conditions, it can form a regular crystalline structure. The crystalline morphology and lattice parameters have a significant impact on its physical and chemical properties, such as affecting its optical and electrical properties, laying the foundation for its application in the field of optical materials and electronic devices.
    The physical properties of 2,6-bis (2-benzimidazolyl) pyridine, from morphology, melting point, solubility, thermal stability to crystallization properties, are interrelated and jointly determine its potential application value in many fields. It is a compound with considerable research and application prospects.
    What are the precautions for using 2,6-Bis (2-benzimidazol-2-yl) pyridine?
    2% 2C6 - Bis% 282 - benzimidazol - 2 - yl% 29pyridine, that is, 2,6 - bis (2 - benzimidazole - 2 - yl) pyridine, when using this product, there are a number of precautions, need to be treated with caution.
    First, this product has a specific chemical activity, and when blending with other chemicals, it is necessary to check whether the two are compatible. If mixed rashly, it may cause the chemical reaction to get out of control, and the product is impure in the lighter case, and dangerous accidents such as fever, fire or even explosion in the worse case. Gu Yun: "The caution of combining medicine is like walking on thin ice in the abyss." Therefore, every time it is compatible with a new agent, it must be tested in a small amount first, and its changes must be carefully observed to confirm that it is safe and secure, so that it can be operated on a large scale.
    Second, during use, protective measures must be taken. This substance may be harmful to the human body, and contact with the skin can cause allergies and burns. If it is not carefully entered into the eyes, it is even more harmful. Therefore, complete protective equipment is required, such as chemical-resistant gloves, goggles, protective clothing, etc. Just like killing the enemy in battle, the armor is complete, so that you can keep yourself safe. After the operation, it is also necessary to properly clean up, so that the residual agent does not endanger the safety of yourself and others.
    Third, storage conditions should not be ignored. It should be placed in a dry, cool and well-ventilated place, away from fire and heat sources. Due to its chemical properties, improper storage or deterioration, loss of original efficacy. Just like storing grain in a warehouse, it must be dry and cool in order to keep it intact for a long time. At the same time, it needs to be stored separately from oxidizing agents, acids, alkalis, etc., to avoid interaction and unnecessary changes.
    Fourth, the user should have a thorough understanding of its nature, use, and risk. Those who do not know this should not operate rashly. Just like operating a boat in water, if they are not familiar with water-based channels, they will inevitably cause the risk of capsizing. Operators should be professionally trained and know the emergency treatment methods. In the event of an accident, they can also respond calmly to minimize losses.