2 5 Pyridinecarboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,5-PYRIDINECARBOXYLIC ACID

    Specifications

    HS Code

    140322

    Name 2,5-Pyridinecarboxylic acid
    Molecular Formula C6H5NO2
    Molecular Weight 123.11 g/mol
    Appearance White to off - white solid
    Melting Point 194 - 196 °C
    Boiling Point Decomposes
    Solubility In Water Soluble
    Pka 3.69 (for the carboxylic acid group)
    Odor Odorless

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    General Information
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    Frequently Asked Questions

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    What are the chemical properties of 2,5-pyridinedicarboxylic acid?
    2% 2C5 - to its succinic acid, this is an organic compound. Its mild nature, with the following characteristics:
    First, physical properties. Often white crystalline, delicate to the touch, moderate melting point, about 185 to 187 degrees Celsius. Stable at room temperature, the smell is light, almost inaudible. And its solubility is unique, slightly soluble in cold water, but easily soluble in hot water and organic solvents such as ethanol and acetone, just like fish get water and integrate into the organic environment.
    Second, chemical properties. It contains dicarboxylic groups, which are common to carboxylic acids. It can be neutralized with alkali, just like yin and yang, to form succinate and water. Taking sodium hydroxide as an example, the combination of the two phases results in sodium succinate and water, which is a model of acid-base neutralization. It can also be esterified with alcohols. When co-placed with ethanol, under suitable conditions, diethyl succinate and water can form a good relationship, forming new substances and emitting a unique fragrance. In addition, under specific catalysts and conditions, it can also participate in polymerization reactions to build polymer compounds, like building magnificent buildings and expanding its application domain.
    Third, the activity of the reaction. Although it contains dicarboxyl groups, its reactivity is not violent and relatively mild. In many reactions, suitable temperature, catalyst and other conditions are required to assist in order to proceed smoothly. Just like a cautious person, complete conditions are required to act.
    Fourth, stable state. In general environments, it is quite stable and not easy to react spontaneously. In case of strong oxidants, or extreme conditions such as high temperature and high pressure, the structure may be damaged, and the properties will also change, just like throwing boulders into a calm lake, breaking the original tranquility.
    To sum up, 2% 2C5-succinic acid, with its unique physical and chemical properties, has important uses in many fields such as chemical industry, medicine, food, etc., adding luster to human life and promoting the progress of science and technology.
    What are the common application fields of 2,5-pyridinedicarboxylic acid
    2% 2C5 - succinic acid is a common organic compound and is used in many fields. In the field of medicine, it can be used as a raw material for drug synthesis. In the molecular structure of many drugs, the structural unit of succinic acid participates in it, and is connected with other chemical groups through specific chemical reactions to build drug molecules with specific pharmacological activities. For example, some drugs used to regulate metabolism in the body and improve physiological functions, succinic acid is a key starting material in its synthesis process, which has a great impact on the final activity and efficacy of drugs.
    In the food industry, succinic acid can be used as a food additive. Because of its unique flavor, it can be used to adjust the taste and flavor of food. In the production of beverages, candies and other foods, an appropriate amount of succinic acid is added, which can give the food a different sweet and sour taste, enhance the flavor level of the food, and enhance the consumer's eating experience. And its safety has been recognized and meets the relevant standards of food additives.
    Furthermore, in the chemical industry, succinic acid is an important chemical raw material. It can be used to synthesize polymer materials such as polyester and polyamide. Polyester resins with excellent performance can be prepared by condensation reaction of succinic acid and polyols. Such polyester resins are widely used in plastics, fibers and other industries, such as the production of packaging materials, textile fibers, etc. They are important basic materials for the chemical industry and promote the diversification and high-performance development of related products.
    In addition, succinic acid also plays an important role in the biological fermentation industry. Many microorganisms can ferment and produce succinic acid under specific culture conditions. This biosynthetic pathway has attracted much attention due to its green and sustainable advantages. By optimizing microbial strains and fermentation processes, the yield and purity of succinic acid can be improved, providing a new path for the large-scale production of succinic acid, which is also in line with the current concept of green chemistry and sustainable development.
    What are the synthesis methods of 2,5-pyridinedicarboxylic acid?
    2% 2C5 - The synthesis method of succinic acid to it covers all kinds. The following are described in detail:
    First, it can be obtained by hydrolysis of succinonitrile. Take succinonitrile as the starting material, and use acid or base as the catalyst to hydrolyze it. If acid catalysis is used, strong acids such as sulfuric acid and hydrochloric acid are often used. At appropriate temperature and time, succinonitrile is first hydrolyzed to butylamide, and then further hydrolyzed to succinic acid. Taking sulfuric acid as an example, succinonitrile is mixed with sulfuric acid in a certain proportion, heated to an appropriate temperature, and the reaction is maintained for a period of time. After that, succinic acid can be obtained through steps such as neutralization, separation, and purification. In alkali-catalyzed hydrolysis, strong bases such as sodium hydroxide are commonly used, and the reaction mechanism is also gradual hydrolysis. However, the conditions may be different from acid catalysis, and subsequent treatment needs to be meticulous to obtain pure succinic acid.
    Second, butanediol oxidation method. Select butanediol as the substrate, and use a suitable oxidant to promote its oxidation to produce succinic acid. If strong oxidants such as potassium permanganate and potassium dichromate are used, under suitable reaction media and conditions, butanediol can be gradually oxidized. When potassium permanganate is oxidized, attention should be paid to controlling the reaction temperature, pH and the amount of potassium permanganate. Because of its strong oxidation, if the conditions are improper, it is easy to cause excessive oxidation and reduce the yield of succinic acid. Catalytic oxidation can also be used, such as a transition metal catalyst, in the presence of oxygen or air, to oxidize butanediol to succinic acid. This method is relatively green and environmentally friendly, and selective or adjustable.
    Third, maleic anhydride is used as raw material. Maleic anhydride can be converted into succinic acid by catalytic hydrogenation. Commonly used catalysts include palladium carbon, Raney nickel, etc. Under appropriate temperature, pressure and catalyst dosage, hydrogen is introduced, and the double bond of maleic anhydride is hydrogenated to form succinic acid. In this process, the optimization of hydrogenation conditions is crucial. Excessive temperature or pressure, or side reactions occur, which affect product quality and yield. The hydrolysis step also needs to be carefully controlled to completely convert the anhydride to succinic acid.
    All synthesis methods have their own advantages and disadvantages, and need to be carefully selected according to actual needs, such as the availability of raw materials, cost, product quality requirements, etc., to achieve the best synthesis effect.
    How is the solubility of 2,5-pyridinedicarboxylic acid in different solvents?
    How is the solubility of 2% 2C5-succinic acid in different solvents? This is a question about the solubility characteristics of substances. Let me tell you one by one.
    2,5-succinic acid, in polar solvents, may have different behaviors. Water is a common polar solvent. 2,5-succinic acid in water, because the molecular structure contains carboxyl groups, can form hydrogen bonds with water molecules, so it has a certain solubility. However, its solubility is not infinite, and temperature and other factors affect it. When the temperature increases, the thermal movement of the molecule intensifies, and more solute molecules can break free from the lattice binding and enter the solution, and the solubility may increase.
    Ethanol is also a polar solvent, which has similarities with water, but the polarity of ethanol is weaker than that of water. 2,5-Dimensional succinic acid has different solubility in ethanol or water. Because of the different forces between molecules and ethanol, or the solubility is different from that in water. Generally speaking, its solubility in ethanol or slightly lower than in water, but it will also change due to conditions such as temperature.
    As for non-polar solvents, such as n-hexane, 2,5-Dimensional succinic acid molecules have polarity, and the force between non-polar solvent molecules is weak, and it is difficult to interact with non-polar solvents to disperse them. Therefore, the solubility in non-polar solvents such as n-hexane is very poor, and it is almost insoluble.
    In summary, 2,5-succinic acid has a certain solubility in polar solvents such as water and ethanol, and is affected by factors such as temperature; in non-polar solvents, it has poor solubility. This is the general situation of its solubility in different solvents.
    What is the approximate market price of 2,5-pyridinedicarboxylic acid?
    2% 2C5-dihydroxyterephthalic acid, that is, 2,5-dihydroxyterephthalic acid, this substance is at the market price, depending on the current market conditions, between 500 and 1,000 yuan per kilogram. Its price is not static and is actually influenced by multiple factors.
    First, the price fluctuation of raw materials has a great impact on it. If the price of basic chemical raw materials required for the synthesis of 2,5-dihydroxyterephthalic acid rises, the production cost will increase, which in turn will promote the price of finished products to rise; conversely, if the price of raw materials falls, the price of products may also decrease.
    Second, the relationship between market supply and demand is a key factor. When the market demand for 2,5-dihydroxyterephthalic acid is strong and the supply is relatively short, the price will rise; if the market demand is low and the supply is excessive, the price will easily fall.
    Third, the difference between production technology and process is also related to cost and product quality. Advanced production technology may reduce production costs, improve product quality, and gain an advantage in market competition, and its prices may be different. And products produced by different manufacturers have different prices due to uneven quality.
    Fourth, factors such as the macroeconomic environment, policies and regulations should not be underestimated. For example, stricter environmental protection policies may cause some manufacturers to increase environmental protection inputs, affecting production costs and output, and indirectly affecting market prices.
    In summary, the market price of 2,5-dihydroxyterephthalic acid is in a dynamic state, and it is necessary to comprehensively consider the above factors in order to have a more accurate grasp of its price.