2 5 Difluoro 3 Iodopyridine
pyridine pyrrole pyrazine piperidine piperazine

2,5-difluoro-3-iodopyridine

    Specifications

    HS Code

    656901

    Chemical Formula C5H2F2IN
    Molecular Weight 255.977
    Appearance Typically a solid, color may vary (e.g., white to off - white powder)
    Solubility In Water Poor solubility as it is an aromatic heterocyclic compound with halogen substitutions
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc. due to its non - polar nature
    Pka Related to the basicity of the pyridine ring, but the fluorine and iodine substituents will shift the pKa value, exact value needs experimental determination
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    General Information
    Where to Buy 2,5-difluoro-3-iodopyridine in China?
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    Frequently Asked Questions

    As a leading 2,5-difluoro-3-iodopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-difluoro-3-iodopyridine?
    2% 2C5-diene-3-furanone, its main uses are as follows:
    This substance is quite useful in the field of fragrances. Because of its unique aroma, it can increase the complexity and layering of flavors when blending various flavors. In food flavors, it can simulate the aroma of fruits, baking, etc., adding an attractive flavor to food, increasing the richness of its flavor, and enhancing the sensory quality of food. For example, it is used in candies, beverages, baked goods, etc., making it more attractive to consumers.
    In the field of pharmaceutical and chemical industry, it also plays an important role. Due to its special chemical structure, it can be used as an intermediate in organic synthesis. On this basis, chemists can use a variety of chemical reactions to synthesize compounds with specific physiological activities, providing key starting materials for the development of new drugs. For example, through a series of reactions, drugs with antibacterial, anti-inflammatory and other effects can be prepared, which can contribute to human health and well-being.
    Furthermore, in the field of materials science, it can also be seen. It can participate in the preparation of certain functional materials, endowing materials with special physical or chemical properties, such as improving the stability and solubility of materials, and expanding the application range of materials in different fields.
    In summary, 2% 2C5-diene-3-furanone plays an important role in many fields such as fragrance, medicine and chemical industry, and material science due to its unique properties. With the development of science and technology, its application prospects may be broader.
    What are the synthesis methods of 2,5-difluoro-3-iodopyridine?
    There are many methods for the synthesis of 2% 2C5-diene-3-alkynyl groups, and the following are the main ones.
    First, it can be obtained by coupling reaction with suitable precursors containing alkynyl groups and alkenyl groups. For example, halogenated alkenes and alkynyl funds are selected, and cross-coupling is carried out under the action of suitable catalysts. This reaction requires careful selection of catalysts, such as palladium catalysts, which are very active and can effectively promote the reaction. And the reaction conditions are also very critical. The choice of temperature and solvent will affect the reaction yield and selectivity. Generally speaking, under the protection of inert gases and in a suitable organic solvent, a certain temperature range can be controlled to make the reaction occur smoothly.
    Second, synthesized by intramolecular cyclization reaction. If appropriate alkenyl and alkynyl groups exist in the molecular structure at the same time, and their spatial positions are suitable, under specific conditions, molecular cyclization can occur. This process may require the introduction of some activating groups to reduce the activation energy of the reaction and promote the cyclization reaction. For example, with the help of some Lewis acid catalysts, the substrate molecules are activated to promote cyclization between alkenyne and alkenyl, and then the target structure is constructed.
    Third, the rearrangement reaction strategy is used. First, a starting material with a specific structure is prepared, which is converted into the target 2% 2C5-diene-3-alkynyl compound through the rearrangement reaction. There are various rearrangement reaction mechanisms, such as Claisen rearrangement, Cope rearrangement, etc. When designing the synthesis route, the type of rearrangement should be reasonably selected according to the structural characteristics of the starting material and the feasibility of the reaction conditions. Such reactions can often achieve the rearrangement of carbon-carbon bonds and the construction of the target structure under relatively mild conditions.
    Fourth, alkynes are used as the starting material and alkenyl groups are gradually introduced. Alkynes can be functionalized first, such as nucleophilic substitution with halogenated hydrocarbons, and specific substituents are introduced. After a series of transformations such as elimination reactions and addition reactions, the alkenyl structure is gradually constructed, and finally 2% 2C5-diene-3-alkynyl compounds are obtained. This method requires precise control of the reaction conditions at each step to ensure that the reaction proceeds in the expected direction.
    What are the physical properties of 2,5-difluoro-3-iodopyridine?
    The physical properties of 2% 2C5-diene-3-alkyne are as follows:
    This substance may be in a gaseous state at room temperature, but it also changes depending on specific conditions. Its color is pure and transparent, without the disturbance of variegated colors, and the appearance is clear. The smell has a specific smell, but it is not pungent and intolerable. It is unique and can be identified by a keen sense of smell.
    In terms of density, it is slightly heavier than air, and it seems to have a sinking state in the air, just like a stable thing that is unwilling to be frivolous. Its boiling point is not high, and in a warm environment, it is easy to dissolve gas and rise. This property makes it difficult to maintain the shape of a liquid state when it is slightly higher at room temperature. The melting point is also low, and at lower temperatures, it condenses into a solid state, just like sleeping in a cold environment, waiting for the temperature to be Su.
    The solubility is different, and it is difficult to dissolve in water. It is as if it is incompatible with water, and the two meet, and they are distinct. However, in organic solvents, such as ethanol and ether, they can blend infinitely, just like friends meet and accept each other.
    2% 2C5-diene-3-alkylene has strong volatility. In an open environment, it is fleeting, like light smoke in the wind, dissipating and invisible. And because of its unique molecular structure, it is prone to change under the influence of external factors such as light and heat, and its stability is slightly lacking. It is like a delicate flower that requires careful care and avoidance in a suitable environment to ensure its stability.
    What is the market price of 2,5-difluoro-3-iodopyridine?
    What is the value of 2% 2C5-diene-3-heptyne in the market? Let's try to discuss it in the classical style of "Tiangong Kaiwu".
    The price of all things in the world is determined by more than one reason. 2% 2C5-diene-3-heptyne, although not well known to everyone, its price is also dependent on the number.
    First, it depends on its quality. Those who are pure in quality must have a higher price than those who are miscellaneous. If it is refined and refined, and impurities are rare, it is more valuable to the user, and the price should be high.
    Second, it is related to its source. If it is easy to obtain, and the materials are widely available, the price may be easy; if it is difficult to obtain, and the source is scarce, and it is not easy to obtain, or complicated methods are required to control it, the price will be high.
    Third, look at its use. If it is of great benefit to various industries, or is the key to pharmaceuticals, or has special use in chemical industry, and is an indispensable material, then there are many who seek it, and the price will also rise.
    Fourth, the amount is also involved. If the market is flooded, the supply will exceed the demand, and the price will drop; if the world is scarce, the price will rise if there are many who cannot obtain it. < Br >
    Now 2% 2C5-diene-3-heptyne, its quality, source, use, and quantity are unknown, so it is difficult to determine its market median price. However, according to common sense, if the quality is pure, the source is thin, the use is wide and the quantity is small, the price will be high; on the contrary, if the quality is miscellaneous, the source is wide, the use is narrow and the quantity is large, the price will be low. It is necessary to consider the situation carefully before we can know its exact price.
    What are the precautions for storing and transporting 2,5-difluoro-3-iodopyridine?
    When storing and transporting 2% 2C5-diethyl-3-furanone, it is necessary to pay attention to many key matters.
    First, it is related to storage. This substance should be stored in a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, high temperature and humidity are prone to deterioration, so it is necessary to avoid fire and heat sources to prevent danger. It should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. Because different chemical substances come into contact with each other or react violently, endangering safety. At the same time, the storage area should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment for emergencies.
    Second, about transportation. Be sure to ensure that the packaging is complete and sealed before transportation to prevent leakage during transportation. Transportation vehicles should be selected to meet safety standards and equipped with corresponding fire equipment. Drive carefully during transportation to avoid bumps and shocks to prevent package damage. During transportation, drive according to the specified route and do not stop in densely populated areas and places with open flames. If a leak occurs during transportation, emergency measures should be taken immediately to evacuate the surrounding people, isolate the leaking area, and properly handle the leak to avoid pollution to the environment and other hazards.
    In this way, during the storage and transportation of 2% 2C5-diethyl-3-furanone, strictly follow the above points of attention to ensure its safety and stability.