2 5 Dichloropyridine 3 Methanol
pyridine pyrrole pyrazine piperidine piperazine

2,5-Dichloropyridine-3-methanol

    Specifications

    HS Code

    230729

    Chemical Formula C6H5Cl2NO
    Molecular Weight 178.016 g/mol
    Appearance Solid
    Melting Point 74 - 76 °C
    Boiling Point 291.3°C at 760 mmHg
    Density 1.472 g/cm³
    Solubility In Water Insoluble
    Flash Point 129.9°C
    Refractive Index 1.574
    Purity Typically high purity in commercial products

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    General Information
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    Frequently Asked Questions

    As a leading 2,5-Dichloropyridine-3-methanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2,5-dichloropyridine-3-methanol?
    The physical properties of 2% 2C5 -difluoroisotropic-3 -methoxy group are as follows:
    This substance is at room temperature or solid, because its structure contains specific groups that affect the intermolecular forces and arrangement. With a certain melting point, when heated to a specific temperature, the lattice can be overcome, and the solid state turns to liquid state. The specific value of the melting point depends on the intermolecular forces, such as hydrogen bonds between groups, van der Waals force, etc. Molecules contain fluorine atoms, and the fluorine electronegativity is large, which changes the polarity of the molecule and has a role in improving the melting point. Methoxy groups also participate in intermolecular interactions, which comprehensively affect the melting point.
    The solubility of this substance is characterized. In view of its structure, its solubility in organic solvents may be better than that of water. Fluorine atoms and methoxy groups make molecules have a certain lipophilicity. Like common organic solvents such as ethanol, ether, chloroform, etc., due to the principle of similar miscibility, they can interact with the substance to dissolve. Water is a polar strong solvent, and the polarity of the substance does not match that of water, and its solubility in water is poor.
    Its density is also restricted by structure. The fluorine atoms in the molecule have a large relative mass. Although the atomic radius is small, it contributes to the overall density. Methoxy groups increase the molecular mass and affect the spatial arrangement, which makes the density of the substance higher than that of some common organic compounds. < Br >
    In appearance, when pure, it may be colorless crystal or white powder, which is due to the absorption and reflection characteristics of its molecular structure to light. The structure does not contain a large number of chromophores such as conjugated systems, and usually has no obvious color.
    Volatility, due to the presence of a certain force between molecules, the volatility is not strong. Fluorine atoms and methoxy groups enhance the bonding force between molecules, so it takes more energy for molecules to break away from the liquid or solid surface and enter the gas phase, so they evaporate slowly at room temperature and pressure.
    What are the chemical properties of 2,5-dichloropyridine-3-methanol?
    The chemical properties of 2% 2C5-dihydroxybenzoic acid-3-methoxy group belong to the category of chemical properties of organic compounds. This substance is acidic because it contains carboxyl groups (-COOH) and hydroxyl groups (-OH). The carboxyl group can release protons, which are acidic in aqueous solution and can neutralize with bases. For example, it interacts with sodium hydroxide (NaOH) to form the corresponding carboxylate and water.
    Furthermore, its hydroxyl groups are also active. The neighboring and para-site electron clouds of phenolic hydroxyl groups have high density and are vulnerable to attack by electrophilic reagents, and can undergo electrophilic substitution reactions such as halogenation and nitrification. Taking halogenation as an example, under appropriate conditions, bromine can replace the hydrogen atoms of the adjacent and para-sites of phenolic hydroxyl groups. < Br >
    Although its methoxy group (-OCH 🥰) is relatively stable, it can also participate in the reaction under certain conditions. In case of strong nucleophiles, it may initiate the substitution reaction of methoxy groups.
    In addition, this compound should have a certain solubility in polar solvents because it contains multiple polar groups. And hydrogen bonds can be formed between molecules, which also affects its physical properties such as melting point and boiling point. Because its structure contains benzene rings and has a certain conjugated system, it should have characteristic absorption in the ultraviolet region, which can be used for qualitative and quantitative analysis.
    What are the main uses of 2,5-dichloropyridine-3-methanol?
    2% 2C5-dihydroxyacetophenone-3-methyl ether, this is an organic compound. Its main uses are quite extensive, and it is often used as a key intermediate in drug synthesis in the field of medicine. Because this compound has a specific chemical structure and activity, it can be chemically modified and reacted to derive many physiologically active drug molecules for the treatment of diseases.
    In the fragrance industry, it also has important applications. Due to its unique chemical composition, it can endow fragrances with unique aroma characteristics, providing the possibility for the preparation of new fragrances, adding the richness and uniqueness of fragrances.
    Furthermore, in the field of organic synthesis, as an important intermediate, it participates in the construction of many complex organic molecules. With its specific functional groups, it can carry out a variety of chemical reactions, such as nucleophilic substitution, redox, etc., to help synthesize organic compounds with novel structures and unique functions, and to contribute to the development of organic synthetic chemistry.
    In the dye industry, it may also play a role. With its chemical structure and properties, it may participate in the synthesis of dye molecules, endowing dyes with good color fastness, bright color and other characteristics to meet different dyeing needs. In short, 2% 2C5-dihydroxyacetophenone-3-methyl ether has important uses in many fields that cannot be ignored.
    What are the synthesis methods of 2,5-dichloropyridine-3-methanol?
    There are various methods for the synthesis of 2% 2C5-dihydroxypyridine-3-acetaldehyde. First, it can be started from a pyridine derivative. First, take a suitable pyridine substrate and react with an aldehyde-based reagent under specific conditions. For example, choose a pyridine containing modifiable groups, and introduce an aldehyde group in an exquisite way. This requires detailed control of the reaction conditions, such as temperature, solvent and catalyst selection. If the temperature is too high, it may cause a cluster of side reactions, and if it is too low, the reaction will be delayed.
    Second, it is converted from the route commonly used in organic synthesis through multiple steps. Starting from the basic raw materials, through a series of reactions such as halogenation, substitution, and oxidation. The first halogenated pyridine is introduced into the halogen atom at a specific position, and then the substitution reaction is carried out to connect the appropriate group, and the required carbon chain is gradually constructed. Finally, the aldehyde group is successfully obtained through the oxidation step. In this process, the sequence and conditions of each step of the reaction need to be carefully designed, and each step is related to the purity and yield of the final product.
    Third, you can try to use the reaction path of metal catalysis. With the help of the unique activity of metal catalysts, the efficient reaction between pyridine substrates and aldehyde reagents can be promoted. Metal catalysts can reduce the activation energy of the reaction and speed up the reaction process. However, it is necessary to choose the suitable metal catalyst and ligand, while paying attention to the pH of the reaction system and other influencing factors, in order to achieve the effective synthesis of the target product. All these methods have their own advantages and disadvantages. In practice, the appropriate synthesis path should be carefully selected according to the availability of raw materials, cost considerations, and the requirements for product purity.
    What should be paid attention to when storing and transporting 2,5-dichloropyridine-3-methanol?
    When storing and transporting 2% 2C5-difluoroisotropic-3-methoxy, pay attention to the following matters:
    First, when storing, find a cool, dry and well-ventilated place. This is because the substance may be sensitive to heat, and high temperature can easily cause its properties to change, or even cause danger. If the environment is humid, it may also make the substance damp and affect its quality.
    Second, it must be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to its special chemical properties, contact with the above substances is very likely to cause violent chemical reactions, or cause disasters such as combustion and explosion.
    Third, the storage place should be equipped with suitable materials to contain the leakage. In case of leakage, it can be properly handled in time to avoid its spread and cause harm to the environment and personnel.
    As for transportation, the transportation vehicle must ensure that the vehicle is in good condition and has corresponding safety facilities. During transportation, strict attention should be paid to avoid collisions and bumps to prevent material leakage due to damaged packaging. At the same time, transportation personnel need to be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. In the event of an emergency, they can respond quickly and correctly to minimize losses and hazards. Furthermore, the relevant transportation regulations and standards must be strictly followed during transportation to ensure that the transportation process is legal and legal, and to ensure transportation safety.