2 5 Dichloropyridine 3 Boronic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,5-Dichloropyridine-3-boronic acid

    Specifications

    HS Code

    560020

    Chemical Formula C5H4BCl2NO2
    Molecular Weight 190.804 g/mol
    Appearance White to off - white solid
    Cas Number 1072952-86-4
    Purity Typically high purity for synthesis, e.g., 97%+
    Solubility Soluble in some organic solvents like dichloromethane
    Melting Point 135 - 140 °C (approximate)
    Storage Conditions Store in a cool, dry place away from oxidizing agents

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    General Information
    Where to Buy 2,5-Dichloropyridine-3-boronic acid in China?
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    Frequently Asked Questions

    As a leading 2,5-Dichloropyridine-3-boronic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-dichloropyridine-3-boronic acid?
    2% 2C5-dihydroxybenzoic acid-3-sulfonic acid, which is an important organic compound with a wide range of main uses.
    In the field of medicine, it can be used as a key intermediate in drug synthesis. The preparation of many drugs requires this as the basic raw material, and a series of chemical reactions are used to supplement specific functional groups to construct drug molecules with specific pharmacological activities. For example, in the synthesis path of anti-inflammatory and analgesic drugs, 2% 2C5-dihydroxybenzoic acid-3-sulfonic acid can play the role of starting material, which can be converted into drugs with ideal therapeutic effects through ingenious chemical modification.
    In the dye industry, it also plays an important role. Due to its molecular structure containing specific functional groups, it can participate in the construction of dye molecules. With its unique chemical properties, it can endow dyes with good dyeing properties, such as color brightness, light resistance and washable properties. It can be used as an important component in the synthesis of new dyes, providing high-quality dye products for textile, printing and dyeing industries.
    In the field of materials science, it can be used to prepare functional materials. By reacting or compounding with other compounds, it can impart specific properties to the material. If this compound is introduced into some polymer materials, it can improve the oxidation resistance and thermal stability of the material, and expand the application of the material in different fields, such as aerospace, electronic devices and other fields that require strict material properties.
    2% 2C5-dihydroxybenzoic acid-3-sulfonic acid, with its diverse chemical properties, has shown indispensable value in many fields such as medicine, dyes, materials, etc., and has promoted technological development and product innovation in various fields.
    What are the synthesis methods of 2,5-dichloropyridine-3-boronic acid?
    The synthesis method of 2% 2C5-difluoropyridine-3-boronic acid involves many chemical channels, which are described in detail today.
    First, pyridine derivatives are used as starting materials. After halogenation, halogen atoms are introduced at specific positions, such as with suitable halogenating reagents, reacted in suitable temperatures and solvents, halogenated pyridine derivatives can be obtained. Subsequently, through metallization, reagents such as butyl lithium are used to form metal-organic intermediates at specific positions of halogenated pyridine, which are highly active. Then react with borate esters, such as trimethoxy borate, slowly add dropwise at low temperature, and through a series of transformations, the target product 2% 2C5-difluoropyridine-3-boronic acid can be obtained. This process requires precise control of the reaction conditions, temperature and reagent dosage are all key.
    Second, the fluorine-containing block method can also be used. Select fluorine-containing compounds with suitable active groups and react with boron-containing blocks. For example, certain fluorohalogenated aromatics and borane derivatives undergo coupling reactions in an alkaline environment under the action of transition metal catalysts such as palladium catalysts. This reaction requires screening suitable catalysts, bases and solvents, such as potassium carbonate as a base and dichloromethane as a solvent, to precisely regulate the reaction conditions, so that the reaction can efficiently and selectively generate the target product.
    Third, the pyridine ring can also be constructed from the construction of pyridine rings. Using fluorine and boron-related raw materials, pyridine rings are constructed through multi-step cyclization. For example, specific fluoroalkenyl amines and boron-containing α-halogenated carbonyl compounds are catalyzed by Lewis acid. Nucleophilic addition first occurs, and then intramolecular cyclization forms a pyridine ring structure. After subsequent modification, 2% 2C5-difluoropyridine-3-boronic acid can be obtained. This path requires fine design of reaction steps to effectively separate and purify intermediates.
    All synthesis methods have their own advantages and disadvantages. According to actual needs, factors such as the availability, cost, yield and purity of raw materials should be considered, and the good ones should be selected and used to achieve the purpose of efficient synthesis.
    What are the physical and chemical properties of 2,5-dichloropyridine-3-boronic acid?
    2% 2C5-dihydroxybenzoic acid-3-sulfonic acid, this is an organic compound. Its physical and chemical properties are unique and have far-reaching impact on many fields.
    Looking at its physical properties, it may be white to light yellow crystalline powder under normal conditions, with a certain melting point, and will melt into a liquid state at a specific temperature. Its solubility also has characteristics. It may have a certain solubility in water, but it may vary in solubility in organic solvents. This solubility characteristic makes the substance behave differently in various solution systems. When used in chemical, pharmaceutical and other fields, it is related to whether it can be uniformly dispersed and participate in the reaction.
    On its chemical properties, the molecule contains hydroxyl groups, carboxyl groups and sulfonic acid groups, so it has corresponding chemical activity. The hydroxyl group can participate in the esterification reaction and react with the acid to form ester compounds; the carboxyl group has significant acidity and can neutralize with the base to form the corresponding carboxylate. The sulfonic acid group is also acidic, which can enhance the solubility and ionization tendency of the substance in water, and plays a role as a catalyst in some chemical reactions. At the same time, these functional groups interact with each other or cause changes in the stability of the substance. Pay attention to environmental factors such as temperature, humidity and pH during storage and use to avoid chemical reactions and cause changes in its properties.
    2% 2C5-dihydroxybenzoic acid-3-sulfonic acid has a wide range of applications in chemical synthesis, drug development, materials science and other fields. Making good use of its characteristics can contribute to the development of various fields.
    What is the price range of 2,5-dichloropyridine-3-boronic acid in the market?
    There is a question today, what is the price of 2252fluoro-tricarboxylic acid in the market? This is a chemical product, and the price state between the markets is often changed due to the purity of the quality and the situation of supply and demand.
    Generally speaking, if the quality is pure and refined, the price may be high; if the quality is heterogeneous and the supply exceeds the demand, the price will be slightly reduced. Looking at the market conditions, the price of such chemicals is about tens to hundreds of gold per gram.
    However, this is only an approximate number. The actual price depends on the current market conditions, the price of the producer, and the volume of transactions. If you want an accurate price, you can get the real price now by consulting the merchant of chemical materials or the platform of chemical trading.
    What are the storage conditions for 2,5-dichloropyridine-3-boronic acid?
    2% 2C5-dihydroxybenzoic acid-3-sulfonic acid, this is a very important compound. Its storage conditions are as follows:
    It should be stored in a cool, dry and well-ventilated place. This compound is quite sensitive to temperature, and high temperature can easily cause its chemical properties to change, which in turn affects its quality and utility. Therefore, it needs to be stored in a low temperature environment. Generally speaking, the temperature should be maintained at 2-8 ° C. Refrigeration conditions are appropriate.
    At the same time, the compound should avoid long-term contact with air. Because of its oxidizing properties, it is easy to react with oxygen when exposed to air, causing it to deteriorate. Therefore, make sure that the container is tightly sealed when storing to isolate the air.
    In addition, it is necessary to keep away from fire and heat sources. This compound may be flammable to a certain extent, and there is a safety risk in case of open flames and hot topics. Therefore, fireworks are strictly prohibited in the storage area, and all kinds of heat source equipment are kept away.
    Furthermore, avoid mixing with other chemical substances. Due to its active chemical nature, contact with certain substances may cause chemical reactions, which can damage its structure and performance. When storing, it should be stored separately and separated from different types of chemicals such as acids, bases, and oxidizers to prevent mutual influence.
    During storage, it should also be checked regularly to see if the packaging is intact, whether there is leakage, and whether there are any abnormal changes in the properties of the compound, such as color and odor changes, so as to detect problems in time and take corresponding measures. In this way, the quality and stability of 2% 2C5-dihydroxybenzoic acid-3-sulfonic acid during storage can be guaranteed.