2 5 Dichloro 4 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2,5-Dichloro-4-(trifluoromethyl)pyridine

    Specifications

    HS Code

    506577

    Chemical Formula C6H2Cl2F3N
    Molecular Weight 215.99
    Appearance Typically a solid (appearance can vary based on purity and conditions)
    Physical State At Room Temperature Solid
    Boiling Point Data may vary, generally in a certain temperature range relevant to its molecular structure
    Melting Point Specific melting point value relevant to its crystal structure
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform etc.
    Density A specific density value related to its mass - volume relationship
    Vapor Pressure Relatively low vapor pressure due to its solid state at room temperature

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    General Information
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    Frequently Asked Questions

    As a leading 2,5-Dichloro-4-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-dichloro-4- (trifluoromethyl) pyridine?
    2% 2C5 -difluoro-4- (trifluoromethyl) pyridine, which is a crucial raw material in the field of organic synthesis. In the field of medicinal chemistry, it plays a key role and is often used as a key intermediate in the synthesis of many specific drugs. For example, in the creation of antibacterial and antiviral drugs, its structural properties can impart unique activity to drug molecules, help improve the binding ability of drugs to targets, and enhance drug efficacy.
    In the field of pesticide chemistry, it also occupies an important position. It can be used to develop high-efficiency, low-toxicity and environmentally friendly pesticides. Due to its special chemical structure, pesticides can have stronger biological activity and selectivity, and can accurately act on pests, reducing the adverse effects on beneficial organisms and the environment.
    In the field of materials science, 2% 2C5 -difluoro-4- (trifluoromethyl) pyridine also shows unique value. It can participate in the synthesis of polymer materials with special properties, such as materials with excellent thermal stability, chemical stability and electrical properties, and has wide application prospects in high-end fields such as electronic devices and aerospace.
    It can be seen from the above that 2% 2C5 -difluoro-4- (trifluoromethyl) pyridine has indispensable uses in many key fields such as medicine, pesticides, and materials due to its unique chemical structure, which is of great significance to promoting the development of related industries.
    What are the physical properties of 2,5-dichloro-4- (trifluoromethyl) pyridine?
    2% 2C5 -difluoro-4- (triethylamino) pyridine is a unique organic compound with various unique physical properties.
    Looking at its properties, under normal temperature and pressure, it often appears as a colorless to light yellow transparent liquid. This state makes it easy to disperse and mix in many reaction systems, creating favorable conditions for the smooth development of the reaction.
    When it comes to the boiling point, it is about a certain temperature range and may fluctuate depending on the specific measurement conditions. This boiling point characteristic determines that it can be effectively distinguished from other substances by means of distillation during the separation and purification process. The value of the boiling point also reflects the strength of the intermolecular forces, indicating the stability and volatility of its structure. < Br >
    Its melting point also has a specific range, and this parameter has a great influence on its crystallization, solid storage and processing. The appropriate melting point makes it possible to store stably in solid form under specific conditions, and also provides the possibility for it to participate in some reactions that require precise temperature control.
    In terms of solubility, it shows good solubility in common organic solvents such as ethanol, ether, dichloromethane, etc. This property greatly expands its application in the field of organic synthesis. It can be used as a reactant, solvent or catalyst carrier to flexibly participate in various chemical reactions, so that the reaction can be carried out efficiently in homogeneous systems, improving the reaction rate and product purity.
    Density is also one of the important physical properties. Compared with common solvents or reactants, its density shows a specific value. This density difference is different from mixing, stratification and other operations, which has practical application value, and helps the experimenter to realize the separation and enrichment of compounds by means of density difference.
    In addition, its vapor pressure varies accordingly at different temperatures. Vapor pressure is related to its volatility, which is of great significance to the safety of the operating environment and the precise control of reaction conditions. Low vapor pressure compounds evaporate less during operation, which can reduce the concentration of harmful gases in the laboratory and ensure the health of the experimenter; and the change law of vapor pressure with temperature also provides a key reference for the optimization of reaction conditions.
    In conclusion, many physical properties of 2% 2C5 -difluoro-4- (triethylamino) pyridine are interrelated, which together determine its application and value in organic synthesis, medicinal chemistry and other fields.
    What are the synthesis methods of 2,5-dichloro-4- (trifluoromethyl) pyridine?
    The synthesis method of 2% 2C5-difluoro-4- (triethylamino) pyridine can be obtained in many ways.
    First, pyridine is used as the initial raw material, and the halogen atom is introduced into the pyridine ring at a specific position. After the fluorination reaction, the halogen atom is replaced with a fluorine atom to obtain a fluorine-containing pyridine intermediate. The intermediate is then reacted with triethylamine under suitable conditions and undergoes a nucleophilic substitution process, so that the triethylamino is introduced into the designated position of the pyridine ring, and the final target product is 2% 2C5-difluoro-4- (triethylamino) pyridine.
    Second, the pyridine ring structure can be constructed from specific fluorobenzene derivatives. With the help of cyclization reactions, such as the use of fluorobenzene derivatives and specific nitrogen-containing reagents, cyclization is achieved under suitable catalysts and reaction conditions to generate pyridine compounds. This pyridine compound may already contain some target substituents, and then undergo subsequent modifications, such as selectively introducing fluorine atoms and triethylamino groups. When introducing fluorine atoms, suitable fluorine reagents and reaction conditions can be selected to ensure accurate substitution of fluorine atoms; when introducing triethylamino groups, the same reaction mechanism such as nucleophilic substitution is used to achieve the purpose of introducing specific positions to synthesize the target product.
    Third, some novel synthesis strategies can also be considered. For example, with the help of transition metal catalytic reactions, transition metal complexes are used as catalysts to catalyze the reaction between fluorine-containing substrates and triethylamino-containing reagents. Such reactions are often characterized by high efficiency and good selectivity, and can precisely control the position of substituents to effectively synthesize 2% 2C5-difluoro-4- (triethylamino) pyridine. However, this approach requires high catalyst selection and control of reaction conditions, and needs to be explored in detail to find the best reaction parameters.
    What should be paid attention to when storing and transporting 2,5-dichloro-4- (trifluoromethyl) pyridine?
    2% 2C5-difluoro-4- (triethoxy) pyridine When storing and transporting this compound, the following points should be paid attention to:
    One is storage. Because of its nature may be lively, it should be stored in a cool, dry and well-ventilated place. Be sure to avoid direct sunlight. Energy in sunlight may promote photochemical reactions of compounds and cause them to deteriorate. And humid environments can easily trigger reactions such as hydrolysis, which pose a threat to the stability of compounds, so the dryness of the storage environment is crucial. At the same time, it should be stored separately from oxidants, reducing agents, acids, bases and other substances. Due to the structural characteristics of the compound, or violent reactions with the above substances, such as oxidation-reduction reactions, acid-base neutralization, etc., the compound will fail and even cause safety accidents.
    The second is related to transportation. During transportation, it is necessary to ensure that the packaging is intact. Packaging materials need to have good sealing and corrosion resistance to prevent compound leakage. Once leaked, not only will the compound be lost, but it may also cause harm to the environment and transportation personnel. And according to its dangerous characteristics, strictly abide by relevant transportation regulations, such as choosing the appropriate means of transportation and routes. For such compounds containing fluorine and specific organic groups, the potential toxicity and danger need to be considered, and the transportation route should avoid densely populated areas and environmentally sensitive areas to prevent serious impact on many people and fragile ecological environments in unexpected situations. In addition, transport personnel should be professionally trained to be familiar with the characteristics of the compound and emergency treatment methods. In the event of an emergency, they can respond quickly and properly to reduce losses and hazards.
    What is the market outlook for 2,5-dichloro-4- (trifluoromethyl) pyridine?
    There are currently 2,5-dihydro-4- (triethoxy) pyridine, and its market prospects are as follows:
    This product has considerable potential in various fields. In the field of medicine, due to its unique chemical structure, it may provide a key cornerstone for the creation of new drugs. Covering drug development, compounds with unique structures are often used to fit specific biological targets and achieve the purpose of treating diseases. This pyridine derivative may be delicately modified and modified to obtain pharmacologically active molecules that can be used to deal with a variety of diseases, such as inflammation, cardiovascular diseases, etc. Its prospects are like uncultivated fertile soil, with endless possibilities.
    In the field of materials science, it also has the opportunity to emerge. With the advance of science and technology, the need for high-performance materials is increasing day by day. 2,5-dihydro-4- (triethoxy) pyridine can be used as a precursor or functional additive, and can be integrated into the preparation of polymer materials and composites. Through its intervention, the properties of materials such as mechanical strength, thermal stability, conductivity, etc. may be significantly improved, thus meeting the stringent requirements of high-end fields such as electronics and aerospace.
    Furthermore, in the field of organic synthesis, it is an important intermediate, like a brick and stone that builds a complex building of organic molecules. With its lively reaction check point, chemists can use various organic reactions to construct complex and functionally specific organic compounds, greatly enriching the "treasure house" of organic synthesis, and injecting new vitality into the fields of fine chemicals and total synthesis of natural products.
    However, in order to fully exploit its market potential, it also faces several challenges. The optimization of the synthesis process is the top priority, and it is necessary to find an efficient, green and economical preparation path to reduce production costs, improve yield and purity, and gain a head start in the market competition. And in-depth study of its properties and applications is also indispensable. Only by gaining a detailed understanding of its behavior under different conditions can it expand its application boundaries and turn potential advantages into actual market shares.
    In summary, although there are obstacles ahead for 2,5-dihydro-4- (triethoxy) pyridine, its promise in the fields of medicine, materials, and organic synthesis indicates that it has a bright and broad market prospect, and it is urgent for people of insight to work together to develop it.