2 5 Dichloro 4 Pyridinecarboxylicacid
pyridine pyrrole pyrazine piperidine piperazine

2,5-dichloro-4-pyridinecarboxylicacid

    Specifications

    HS Code

    694231

    Name 2,5 - dichloro - 4 - pyridinecarboxylic acid
    Molecular Formula C6H3Cl2NO2
    Molecular Weight 192.00
    Appearance Solid (usually white or off - white)
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Data needed
    Solubility In Organic Solvents Data needed
    Pka Value Data needed
    Density Data needed
    Chemical Reactivity Reactive towards nucleophiles due to the presence of chlorine atoms and the carboxylic acid group

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    General Information
    Where to Buy 2,5-dichloro-4-pyridinecarboxylicacid in China?
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    Frequently Asked Questions

    As a leading 2,5-dichloro-4-pyridinecarboxylicacid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2,5-dichloro-4-pyridinecarboxylic acid?
    2% 2C5-difluoro-4-cyanobenzoic acid is an organic compound with unique chemical properties. It is acidic, because the carboxyl group can dissociate hydrogen ions in solution, participate in acid-base reactions, and react with bases to form corresponding carboxylic salts and water. For example, when reacted with sodium hydroxide, 2% 2C5-difluoro-4-cyanobenzoic acid and water will be formed.
    Cyanyl groups in this compound are active. Cyanyl groups can undergo various reactions, such as hydrolysis reactions. Under the catalysis of acids or bases, cyanyl groups can be gradually converted into carboxyl groups, amide groups, etc. If hydrolyzed under acidic conditions, the cyano group is first converted to an amide group, and then further hydrolyzed to a carboxyl group, which can change the molecular structure and derive different compounds.
    The fluorine atoms it contains give the compound special properties. Fluorine atoms are highly electronegative, which affects the distribution of molecular electron clouds and enhances molecular stability and fat solubility. This makes 2% 2C5-difluoro-4-cyanobenzoic acid interesting in some fields of organic synthesis and medicinal chemistry. Because the increase in fat solubility facilitates its passage through biofilms, it may have unique advantages in drug design.
    In addition, the 2% 2C5-difluoro-4-cyanobenzoic acid benzene ring can undergo electrophilic substitution reactions. Due to the high electron cloud density of the benzene ring, it is vulnerable to attack by electrophilic reagents, such as halogenation, nitrification, sulfonation and other reactions, other functional groups can be introduced into the benzene ring, expanding its application in organic synthesis, and synthesizing organic compounds with more complex and diverse structures.
    What are the main uses of 2,5-dichloro-4-pyridinecarboxylic acid?
    2% 2C5-difluoro-4-cyanobenzoic acid, which has important uses in the fields of medicine, pesticides and material synthesis.
    In the field of pharmaceutical synthesis, it is a key intermediate. With its unique chemical structure, molecules with specific pharmacological activities can be constructed through a series of chemical reactions. For example, in the process of anti-cancer drug development, using this as the starting material can introduce specific functional groups, modify the molecular structure, enhance the targeting and inhibitory effect of drugs on tumor cells, and help create new anti-cancer drugs with better efficacy and less side effects.
    In the synthesis of pesticides, 2% 2C5-difluoro-4-cyanobenzoic acid also plays an important role. Compounds with high insecticidal and bactericidal properties can be derived. Through precision chemical design, it exhibits high activity against specific crop diseases and pests, while being environmentally friendly, reducing the impact on non-target organisms, and providing powerful chemical tools for sustainable agricultural development.
    In the field of material synthesis, it can participate in the preparation of functional materials. Such as the preparation of polymer materials with special optical and electrical properties. After polymerization with other monomers, the material is given unique properties and can be used in optoelectronic devices such as organic Light Emitting Diode (OLED) and solar cells to improve device performance and efficiency, and promote the progress and innovation of materials science.
    What are the synthesis methods of 2,5-dichloro-4-pyridinecarboxylic acid?
    To prepare 2,5-difluoro-4-cyanobenzoic acid, there are many methods, and each has its own advantages and disadvantages, and should be selected according to the facts.
    One is the halogenation cyanide method. First take the appropriate aromatic compound, use a specific halogenating agent to perform halogenation, so that fluorine atoms are introduced to obtain fluorine-containing intermediates. Following the cyanide reagent, the cyanide group is connected, and then the side chain is converted into carboxyl groups through the oxidation step. This step is complicated, but the raw materials are common and easy to obtain. If properly controlled, higher yields can be obtained. If there were craftsmen in the past, starting with an aromatic hydrocarbon, halogenated to obtain fluoroaromatic hydrocarbons, after cyanidation and oxidation, and finally obtained this acid. However, during the operation, the control must be fine under the halogenation conditions, otherwise it is easy to produce by-products.
    The second is the direct cyanidation method. Find benzoic acid derivatives containing suitable substituents, and introduce cyanide groups in one step with special cyanidation reagents and conditions, and adjust the position of fluorine atoms at the same time. This path is simple and simple, but the reagent requirements are strict, and the cyanidation reaction conditions are not easy to be pinched, slightly poor, or difficult to react, or produce many impurities. There have been ingenious attempts to simplify the process, but the cyanidation conditions are not good, resulting in poor yield.
    The third is biosynthesis. Using the catalytic properties of microorganisms or enzymes, specific substrates are used to synthesize target products through biological metabolic pathways. This is a green and environmentally friendly method with good selectivity and environmental friendliness. However, the biological system is complex, and specific conditions are required to cultivate microorganisms or extract enzymes, and the yield is often limited. In the past, doctors have explored the method of biosynthesis. Although pure products were obtained, it was difficult to prepare large-scale due to the difficulty of microbial culture.
    There are also those prepared by metal catalytic coupling method. Select suitable halogenated aromatics and cyanide sources, couple them under the action of metal catalysts to form cyanoaromatics, and then modify them to obtain target acids. This method has high selectivity and relatively mild reaction conditions. However, the metal catalyst is expensive and requires cumbersome separation steps. Although some engineers have synthesized this method, the effect is acceptable, but the cost concerns limit its wide use.
    What is the market price of 2,5-dichloro-4-pyridinecarboxylic acid?
    I think what you are asking is about the market price of 2,5-difluoro-4-cyanobenzoic acid. However, the price of this product often changes for many reasons, and it is difficult to determine a certain number.
    First, the supply and demand of the market is the main factor affecting its price. If there are many applicants and few suppliers, the price will increase; conversely, if the supply exceeds the demand, the price will fall. Second, the cost of production also affects the price. The price of raw materials, labor costs, and transportation tariffs are all related to costs. If the cost increases, the price will also rise; if the cost decreases, the price may decrease. Third, competition in the industry also has an impact. < Br >
    In addition, in different places and at different times, the price varies. In prosperous cities, where supply and demand are tight, the price may be high; in remote places, where supply and demand are slow, the price may be low. When the demand is prosperous, the price is always high; when the demand is low, the price is always low.
    Therefore, in order to know the exact market price of 2,5-difluoro-4-cyanobenzoic acid, it is necessary to observe the market dynamics, visit suppliers, industry operators, or refer to relevant market reports, to get a near-real price.
    What are the precautions for storing and transporting 2,5-dichloro-4-pyridinecarboxylic acid?
    When storing and transporting 2% 2C5-difluoro-4-methoxybenzoic acid, it is necessary to pay attention to many matters.
    When storing, the temperature and humidity of the environment should be the first priority. This substance is quite sensitive to temperature and humidity, and high temperature can easily cause it to decompose and deteriorate. If the humidity is too high, it may cause moisture decomposition. Therefore, it should be placed in a cool and dry place. The temperature should be controlled between 15 ° C and 25 ° C, and the relative humidity should be maintained at 40% to 60%.
    Furthermore, attention should be paid to its isolation from other substances. Due to its active chemical nature, it is easy to react with oxidants, reducing agents, etc., so it should not be stored in a room with this kind of substance to avoid danger. At the same time, it is necessary to ensure that the storage space is well ventilated to prevent the accumulation of harmful gases.
    As for the transportation process, the packaging must be solid and reliable. Select high-quality packaging materials to ensure that there will be no damage and leakage during transportation bumps. And the transportation vehicle should have good temperature control and ventilation equipment to meet the temperature, humidity and ventilation requirements of the substance.
    Transportation personnel also need to be familiar with its characteristics and emergency treatment methods. If an accident such as leakage occurs during transportation, it should be dealt with immediately according to the established emergency plan to avoid the expansion of the harm. In addition, transportation route planning should not be ignored. It is necessary to avoid crowded areas and environmentally sensitive areas to prevent serious consequences in the event of leakage. Only in this way can the safety and stability of 2% 2C5-difluoro-4-methoxybenzoic acid be ensured during storage and transportation.