2 5 Dichloro 4 Nitropyridine
pyridine pyrrole pyrazine piperidine piperazine

2,5-dichloro-4-nitropyridine

    Specifications

    HS Code

    329691

    Chemical Formula C5H2Cl2N2O2
    Molar Mass 192.989 g/mol
    Appearance Solid (likely yellow - colored, common for nitro - containing compounds)
    Physical State At Room Temperature Solid
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Low (due to non - polar nature of pyridine ring and hydrophobic chloro and nitro groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc.
    Density Data needed
    Vapor Pressure Low at room temperature
    Pka Data needed
    Reactivity Reactive towards nucleophiles due to the presence of electron - withdrawing nitro and chloro groups

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    Frequently Asked Questions

    As a leading 2,5-dichloro-4-nitropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2,5-dichloro-4-nitropyridine?
    2% 2C5-difluoro-4-cyanopyridine, this substance is a key intermediate in organic synthesis, and is widely used in many fields such as medicine and pesticides. Its physical properties are specific, let me tell you in detail.
    Looking at its appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder, with fine texture, like the first snow in winter, pure and delicate.
    When it comes to the melting point, it is about a specific temperature range. This temperature characteristic is in the synthesis reaction and is of great significance for controlling the reaction process. Just like walking on a boat in water, the water temperature is suitable, and it can go down the river. Its melting point is [specific value], which is obtained by accurate determination and is the key basis for accurate temperature control during synthesis.
    The boiling point is also one of its important physical properties. Under a specific pressure environment, the boiling temperature is fixed, which is an important indicator of the separation and purification process. Its boiling point is [specific value]. At this temperature, the substance changes from liquid to gaseous state, which can be effectively separated from other substances, just like panning for gold in sand, and the desired substance can be accurately screened.
    In terms of solubility, 2% 2C5-difluoro-4-cyanopyridine exhibits a unique performance in organic solvents. In common organic solvents, such as methanol, ethanol, dichloromethane, etc., it has certain solubility. In methanol, it is like a fish getting water, and it can be evenly dispersed in an appropriate proportion to form a clear solution. This solubility facilitates the selection of the medium for the chemical reaction, just like setting the stage, and the appropriate solvent can allow the "actors" of the chemical reaction to perform to their heart's content.
    In addition, its density is also a specific value, [specific density value]. Although this physical parameter seems ordinary, it is indispensable in the process of material measurement, storage and transportation of industrial production. Just like building a tall building, the weight of every inch of masonry needs to be accurately calculated to ensure the stability of the building.
    In summary, the many physical properties of 2% 2C5-difluoro-4-cyanopyridine, like the components of precision instruments, play an indispensable role in chemical synthesis and related industrial applications, laying a solid foundation for its wide application.
    What are the chemical properties of 2,5-dichloro-4-nitropyridine?
    2% 2C5-difluoro-4-cyanopyridine is an important organic compound with unique chemical properties and wide applications in many fields.
    This compound has significant stability. Due to the high electronegativity of fluorine atoms in the molecule, fluorine can strengthen the stability of the molecule, making 2% 2C5-difluoro-4-cyanopyridine difficult to react with other substances in common chemical environments. For example, under normal temperature and pH conditions, it can maintain its own structure for a long time, which makes it very convenient for storage and transportation without special harsh conditions.
    Furthermore, its electrophilicity is also a key property. The presence of cyano and pyridine rings makes the molecule as a whole exhibit a certain electrophilicity. This means that under suitable reaction conditions, 2% 2C5-difluoro-4-cyanopyridine easily reacts with nucleophiles, and then forms new chemical bonds to generate different derivatives. For example, under the catalysis of bases, it can react with alcohol nucleophiles to generate corresponding substitution products. This reaction provides an important path for the construction of more complex molecular structures in organic synthesis.
    Its aromaticity cannot be ignored. The pyridine ring has a typical aromaticity, which endows 2% 2C5-difluoro-4-cyanopyridine with a unique electron cloud distribution and conjugate system. The aromaticity makes the compound exhibit special physical and chemical behaviors under the action of light and heat. If irradiated by a specific wavelength of light, photochemical reactions such as electron transitions may occur, and due to the presence of the conjugate system, the electron fluidity of the molecule is enhanced, which affects its chemical reaction activity and selectivity.
    In addition, the solubility of 2% 2C5-difluoro-4-cyanopyridine is also characterized. It has a certain solubility in organic solvents such as dichloromethane, N, N-dimethylformamide, but relatively small solubility in water. This solubility characteristic is extremely important in the process of organic synthesis and separation and purification, and suitable solvents can be selected for reaction and product separation according to this property.
    What are the main uses of 2,5-dichloro-4-nitropyridine?
    2% 2C5-difluoro-4-cyanopyridine is an important organic compound. Its main uses are quite extensive, and its role is particularly critical in the field of pharmaceutical synthesis.
    Guanfu Pharmaceutical created, among the synthesis pathways of many drugs, 2% 2C5-difluoro-4-cyanopyridine is often a key intermediary. Due to its special chemical structure, it can participate in a variety of chemical reactions and help build complex drug molecular structures. Through specific reaction steps, specific functional groups can be introduced, thus endowing the drug with unique biological activity and pharmacological properties.
    In the field of pesticide research and development, it also has its uses. It can be used as an important starting material for the synthesis of new pesticides. Through clever chemical transformation, pesticide products with high insecticidal, bactericidal or herbicidal properties can be prepared. By precisely designing the molecular structure, the effect of pesticides on target organisms can be enhanced, while reducing the adverse effects on the environment and non-target organisms.
    Furthermore, in the field of materials science, it also shows potential application value. Or it can participate in the synthesis of organic materials with special properties, such as photoelectric materials. With its unique electronic properties and structural characteristics, it imparts specific optical and electrical properties to materials to meet the needs of different fields for special materials.
    In summary, 2% 2C5-difluoro-4-cyanopyridine plays an important role in various fields such as medicine, pesticides, and materials science, and has made significant contributions to the development of related fields.
    What are the synthesis methods of 2,5-dichloro-4-nitropyridine?
    2% 2C5-dihydro-4-pyrimidinylpyridine is an important class of organic compounds, and its synthesis methods are various. The following are described in detail by you.
    First, a simple compound containing pyrimidine and pyrimidine structural units is used as the starting material and synthesized by condensation reaction. This approach requires the selection of suitable reaction conditions and catalysts to improve the reaction efficiency and product purity. If a specific basic catalyst is selected, it can promote the nucleophilic substitution or addition condensation reaction between the two structural units to form the basic skeleton of the target product. However, this method requires quite high purity and reactivity of the starting material, otherwise it is easy to produce side reactions and affect the yield of the product.
    Second, the coupling reaction strategy catalyzed by transition metals is adopted. The unique catalytic performance of transition metal catalysts is used to promote the coupling of pyridine-containing halogenates or other active intermediates with pyrimidine structure. For example, the coupling reaction catalyzed by palladium can precisely construct carbon-carbon or carbon-heteroatom bonds, and effectively synthesize 2% 2C5-dihydro-4-pyrimidinyl pyridine. However, the cost of transition metal catalysts is higher, and the separation and recovery of post-reaction treatment should also be paid attention to to to reduce costs and environmental impact.
    Third, synthesis by cyclization reaction. Select a linear precursor with suitable functional groups to form the target compound through intramolecular cyclization. This process requires fine regulation of reaction conditions, such as temperature, solvent, etc., to ensure the smooth progress of the cyclization reaction. For example, by controlling the activity and spatial position of the functional groups in the precursor molecule, it is promoted to undergo intramolecular cyclization under appropriate conditions to generate 2% 2C5-dihydro-4-pyrimidinylpyridine with a specific structure. However, this method requires high design requirements for the precursor, and its reactivity and cyclization selectivity need to be fully considered.
    When synthesizing 2% 2C5-dihydro-4-pyrimidinylpyridine, the advantages and disadvantages of each method should be weighed according to the actual needs and conditions, and the optimal synthesis strategy should be selected to achieve the synthesis goal of high efficiency, economy and environmental protection.
    What are the precautions for storing and transporting 2,5-dichloro-4-nitropyridine?
    2% 2C5-difluoro-4-cyanopyridine is an extremely important chemical substance. When storing and transporting, many points must be paid attention to:
    First, when storing, it should be placed in a cool, dry and well-ventilated place. This substance is quite sensitive to humidity and temperature. If the environment is humid or the temperature is too high, it is very likely to cause chemical reactions, which will affect the quality. For example, if it is in a humid environment, it may cause reactions such as hydrolysis and damage its chemical structure.
    Second, it must be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to its active chemical properties, contact with the above substances is prone to violent chemical reactions, which may even cause serious accidents such as explosions.
    Third, the storage area should be equipped with suitable materials to contain possible leaks. In order to prevent material leakage due to package damage and other reasons during storage, it can be effectively treated in time to avoid pollution of the environment and other hazards.
    Fourth, during transportation, ensure that the container is well sealed to prevent leakage. Transportation vehicles also need to have corresponding protective measures to avoid packaging damage due to bumps, collisions, etc.
    Fifth, transportation personnel must undergo professional training and be familiar with the dangerous characteristics of the substance and emergency treatment methods. In the event of an unexpected situation during transportation, prompt and correct measures can be taken to minimize the harm.
    All these precautions are related to the safety of 2% 2C5-difluoro-4-cyanopyridine during storage and transportation, and must not be taken lightly.