2 5 Dichloro 4 6 Dimethylpyridine 3 Carboxamide
pyridine pyrrole pyrazine piperidine piperazine

2,5-dichloro-4,6-dimethylpyridine-3-carboxamide

    Specifications

    HS Code

    185340

    Chemical Formula C8H8Cl2N2O
    Molar Mass 221.07 g/mol
    Appearance Solid (appearance may vary)
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Limited solubility (estimate)
    Solubility In Organic Solvents Soluble in some organic solvents (general)
    Density Data needed
    Vapor Pressure Low vapor pressure (estimate)
    Pka Data needed
    Logp Data needed

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    General Information
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    Frequently Asked Questions

    As a leading 2,5-dichloro-4,6-dimethylpyridine-3-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2,5-dichloro-4,6-dimethylpyridine-3-formamide?
    2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formaldehyde, this is an organic compound. It is active and has a wide range of uses in the field of organic synthesis. It is often used as a key intermediate and can participate in a variety of chemical reactions. The main ones are as follows:
    First, nucleophilic addition reaction. Because its aldehyde group is electron-deficient, it is easily attacked by nucleophilic reagents. In case of alcohols, it can be formed into hemiacetal or acetal; in case of amines, imines are produced. This imine can be reduced in subsequent reactions to obtain corresponding amine compounds, which is of great significance for the preparation of drugs and fine chemicals.
    Its second oxidation reaction. The aldehyde group can be oxidized, and it can be oxidized to carboxylic acid with suitable oxidizing agents, such as mild oxidizing agent manganese dioxide; strong oxidizing agents such as potassium permanganate may also affect the pyridine ring, resulting in the formation of more oxidation products.
    Third, condensation reaction. With active methylene-containing compounds, under alkali catalysis, condensation reaction is prone to occur, forming carbon-carbon double bonds, increasing carbon chains, providing an effective way for the construction of complex organic molecules, commonly used in the total synthesis of natural products.
    Fourth, reduction reaction. Under the action of reducing agents, such as sodium borohydride and lithium aluminum hydride, aldehyde groups can be reduced to alcohol hydroxyl groups to obtain hydroxyl-containing pyridine derivatives. This derivative is indispensable in the synthesis of organic molecules with special functions.
    In short, 2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formaldehyde occupies an important position in the field of organic synthesis due to its unique structure and active chemical properties, laying the foundation for the creation of many high-value organic compounds.
    What are the preparation methods of 2,5-dichloro-4,6-dimethylpyridine-3-formamide?
    To prepare 2,5-difluoro-4,6-dimethylpyridine-3-formonitrile, there are various methods.
    First, suitable pyridine derivatives can be used as the starting point, and fluorine atoms can be introduced through halogenation reaction. Choose a pyridine substrate containing the corresponding methyl group, and under suitable reaction conditions, treat it with a specific halogenating agent to introduce fluorine atoms at the 2,5 position. In this process, the reaction temperature, reagent dosage and reaction time must be carefully reviewed, so that the halogenation reaction can occur precisely at the required check point and avoid excessive halogenation or other side reactions.
    Second, the strategy of constructing pyridine rings is also feasible. The synthesis of 2,5-difluoro-4,6-dimethylpyridine-3-formonitrile was achieved synchronously by cyclization reaction with appropriate organic compounds containing nitrile groups and methyl groups as raw materials. This approach requires careful selection of cyclization reagents and reaction conditions. Through reasonable reaction design, the groups can be precisely arranged during cyclization to achieve the construction of the target product.
    Or, intermediates containing part of the target structure can be prepared first, and then gradually modified. For example, the pyridine compound containing specific substituents is synthesized first, and the nitrile group is introduced through cyanylation reaction. At the same time, the reaction conditions are optimized to ensure that the cyanyl group can successfully connect to the third position of the pyridine ring without affecting other existing methyl groups and fluorine atoms.
    All preparation methods need to carefully control the reaction conditions, consider the selection of raw materials, the activity of reagents, and the sequence of reactions, etc., in order to achieve the purpose of preparing 2,5-difluoro-4,6-dimethylpyridine-3-formonitrile with high efficiency and high selectivity.
    In which fields is 2,5-dichloro-4,6-dimethylpyridine-3-formamide used?
    2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-acetaldehyde, which is quite used in the field of pharmaceutical and chemical industry. It is often a key intermediate in the creation of Guanfu Pharmaceutical. Due to its unique chemical conformation, it can be coupled with other compounds through various reactions, thus building a complex and delicate drug molecular structure.
    For example, in the development of antibacterial drugs, it can be used as an important starting material and can be chemically modified to give new compounds excellent antibacterial activity. By linking to specific structural fragments, it can precisely connect to the target in the bacterial body, or interfere with its metabolic pathway, or destroy the synthesis of its cell wall membrane, achieving the effect of bacteriostatic and sterilization.
    Furthermore, in the field of pesticides, it also has good performance. Based on it, pesticide ingredients with high insecticidal and bactericidal properties can be constructed. It can specifically act on the physiological processes of pests and pathogens by virtue of its chemical properties, which is essential for ensuring the healthy growth of crops and improving yields.
    And in the field of materials science, it has also gradually emerged. Because of its structural stability and reactivity, it can be used to prepare special functional materials. For example, in the synthesis of some materials with special requirements for chemical stability and electrical properties, it can be used as a key structural unit to optimize the properties of materials, contributing to the innovative development of materials science.
    What is the market outlook for 2,5-dichloro-4,6-dimethylpyridine-3-formamide?
    2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formamide is a fine organic compound. Its market prospect is quite promising for many reasons.
    First of all, in the field of medicine, as a key intermediate, it can be used to synthesize a variety of specific drugs. At present, the demand for organic compounds with specific structures in pharmaceutical research and development is increasing day by day. The creation of many new drugs requires such fluorine-containing and specific substituent pyridine compounds to enhance drug activity, enhance stability, and optimize pharmacokinetic properties. Therefore, as the pharmaceutical industry continues to pursue innovative drugs, the demand for 2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formamide will rise steadily.
    Secondly, in the field of pesticides, the compound exhibits good biological activity and environmental compatibility due to its unique chemical structure. With the deepening of people's attention to food safety and environmental protection, high-efficiency, low-toxicity and environmentally friendly pesticides have become the mainstream of development. 2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formamide is expected to be a key raw material to participate in the synthesis of new pesticides in line with this trend, and the market potential is huge.
    Furthermore, in the field of materials science, fluorinated organic compounds often have special physical and chemical properties, such as excellent thermal stability, chemical stability and electrical properties. 2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formamide may be used to prepare high-performance polymer materials, electronic materials, etc., to meet the needs of high-end fields such as electronics and aerospace for special materials, thus opening up a broader market space.
    To sum up, 2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formamide has a bright market prospect due to its potential applications in medicine, pesticides, materials science and other fields. It is expected to occupy an important position in the future chemical industry, attracting many enterprises and scientific research institutions to participate in related research and development and production.
    What is the safety of 2,5-dichloro-4,6-dimethylpyridine-3-formamide?
    2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formaldehyde is a key class of intermediates in organic synthesis and is widely used in many fields such as medicine and pesticides. The safety consideration of this substance is extremely important, which is related to human health and environmental safety.
    As far as its toxicity is concerned, due to limited research data, it is difficult to determine the exact toxicity data. However, compounds with similar analogical structures may have certain toxicity. The fluorine atoms, methyl groups and aldehyde groups in their molecules may interact with molecules in organisms and interfere with normal physiological processes. For example, aldehyde groups have high activity, or react with active groups in proteins and nucleic acids, causing abnormal cell function. Therefore, when operating, personnel must take good protection to avoid skin contact and inhalation.
    From the perspective of environmental impact, its degradation status in the environment also needs to be further explored. If it flows into the environment, due to the structure of fluorine, fluorine atoms, carbon and fluorine bonds are stable, or it is difficult to be rapidly degraded by microorganisms, and it remains in the environment for a long time. And it may migrate and transform in soil and water, affecting the ecosystem. For example, it may have toxic effects on aquatic organisms and soil microorganisms, destroying the ecological balance.
    In terms of combustion characteristics, this compound contains carbon, hydrogen, oxygen, nitrogen, fluorine and other elements, and when burned, it may produce harmful gases such as carbon monoxide, carbon dioxide, nitrogen oxides, and hydrogen fluoride. These gases are extremely harmful. Carbon monoxide can cause hypoxia in human tissues, nitrogen oxides form acid rain, chemical fumes, and hydrogen fluoride is highly corrosive, irritating the respiratory tract and skin. Therefore, when storing and using, keep away from fire and heat sources to prevent fires.
    Overall, the safety of 2% 2C5-difluoro-4% 2C6-dimethylpyridine-3-formaldehyde cannot be ignored. Whether it is production, transportation, or use, it is necessary to strictly follow safety regulations and operating procedures. It is necessary to strengthen research on its toxicity and environmental behavior in order to better control risks and protect personnel safety and ecological environment.