2 5 Dichloro 1h Imidazo 4 5 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2,5-Dichloro-1H-imidazo[4,5-b]pyridine

    Specifications

    HS Code

    539585

    Chemical Formula C6H3Cl2N3
    Molecular Weight 188.01
    Appearance Solid (likely white or off - white powder)
    Physical State At Room Temperature Solid
    Melting Point Data may vary, needs experimental determination
    Boiling Point Data may vary, needs experimental determination
    Solubility In Water Low solubility, organic - soluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Density Data may vary, needs experimental determination
    Odor Odorless or faint odor
    Stability Stable under normal conditions, may decompose under high heat or strong oxidizing agents

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    General Information
    Where to Buy 2,5-Dichloro-1H-imidazo[4,5-b]pyridine in China?
    As a trusted 2,5-Dichloro-1H-imidazo[4,5-b]pyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,5-Dichloro-1H-imidazo[4,5-b]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2,5-dichloro-1H-imidazolo [4,5-b] pyridine?
    2% 2C5-difluoro-1H-indolo [4,5-b] pyridine is an organic compound and the like. Its main uses are quite extensive, and it is often used as a key intermediate in the field of medicinal chemistry. Due to its unique chemical structure, many bioactive compounds can be derived through various chemical reactions, and it plays a crucial role in the creation of new drugs, such as anti-cancer, antiviral and neurological diseases.
    In the field of materials science, it also shows potential uses. It may participate in the preparation of materials with special photoelectric properties, which is expected to be applied in the fields of organic Light Emitting Diodes (OLEDs), solar cells, etc. With its structural properties, it endows materials with unique electrical and optical properties and improves the performance of related devices.
    Furthermore, in the field of organic synthetic chemistry, as a special structural unit, it provides organic synthetic chemists with novel synthesis ideas and strategies. Chemists can modify and transform it to construct more complex and diverse organic molecular structures, expand the boundaries of organic synthesis, and enrich the types and functions of organic compounds.
    What are the synthesis methods of 2,5-dichloro-1H-imidazolo [4,5-b] pyridine
    The synthesis method of 2% 2C5-difluoro-1H-indolo [4,5-b] pyridine covers a variety of ways. First, fluorine atoms can be introduced by the corresponding nitrogen-containing heterocyclic precursor through halogenation reaction, and then the indolo-pyridine skeleton can be constructed by cyclization reaction. When halogenating, select a suitable halogenating agent and control the reaction conditions, such as temperature and solvent, to ensure a smooth reaction and obtain the desired product.
    Second, the coupling reaction catalyzed by metal is the main path. Select a metal catalyst with suitable activity, such as palladium, nickel, etc., so that the fluorine-containing aryl halide is coupled with the nitrogen-containing heterocyclic substrate, and then undergoes intramolecular cyclization to eventually form the target compound. In this process, the amount of metal catalyst and the selection of ligands are all related to the efficiency and selectivity of the reaction, and must be carefully studied.
    Or start from the raw material and gradually build the structure of the target molecule through multi-step functional group transformation. First, the starting material is modified with functional groups, and the necessary substituents are introduced. Then, by cyclization and fluorination, the synthesis of 2,5-difluoro-1H-indolo [4,5-b] pyridine is gradually achieved. Although there are many steps in this path, the control of the reaction conditions is more accurate, which can effectively improve the purity and yield of the product.
    The synthesis method has its own advantages and disadvantages, and it needs to be based on the actual situation, such as the availability of raw materials, cost considerations, and the purity requirements of the target product. Only by weighing and choosing the optimal method can the purpose of synthesis be achieved.
    What are the physicochemical properties of 2,5-dichloro-1H-imidazolo [4,5-b] pyridine?
    2% 2C5-difluoro-1H-indolo [4% 2C5-b] pyridine is a unique organic compound. Its physical and chemical properties are of great value for investigation.
    Looking at its physical properties, at room temperature, this compound is mostly in a solid state, but its specific color may vary depending on its purity and preparation method. It is either a white powder or a white-like crystal with a fine texture. The number of its melting point is related to the interaction between molecules and has an important indication of its phase change under specific conditions. After many experiments, its melting point is within a certain range. This value provides basic data for relevant research and applications.
    As for chemical properties, in the structure of 2% 2C5-difluoro-1H-indolo [4% 2C5-b] pyridine, the fused system containing indole and pyridine, this unique structure gives it special chemical activity. The introduction of fluorine atoms greatly affects the electron cloud distribution of the molecule. Due to the strong electronegativity of fluorine atoms, the polarity of the molecule is changed, and in chemical reactions, it can often guide the direction of the reaction. For example, in electrophilic substitution reactions, the neighbors and pairs of fluorine atoms become the activity check points of the reaction due to the change of electron cloud density. At the same time, the compound also exhibits unique properties in some redox reactions, or can be used as an electron donor or receiver to participate in complex chemical conversion processes, and has potential applications in the field of organic synthesis.
    What is the market price of 2,5-dichloro-1H-imidazolo [4,5-b] pyridine?
    I don't know what you said about the market price of 2,5-difluoro-1H-indolo [4,5-b] pyridine. However, if you want to know its price, you should follow various paths.
    First, you can explore the market for chemical materials trading. There, merchants list all kinds of chemical products, or if you have this product, ask the shopkeeper, and you can get its price. However, the market concentration, the price may vary over time, change with quantity, and also vary with the quality.
    Second, visit the website of chemical products. In today's world, the Internet is convenient, and many chemical information can be found online. If you search for this product on a professional chemical website, you can often see quotations from different manufacturers, and you can compare the price of its quality and quantity. However, the price online, or just for reference, may change when purchasing.
    Third, ask the distributor of chemical products. They often deal with manufacturers and users, and are familiar with various product market conditions. With their experience and channels, they can tell you a more accurate price. However, the price given by the distributor, or including its profit, should also be carefully examined. < Br >
    To obtain the exact price of this 2,5-difluoro-1H-indolo [4,5-b] pyridine, the approximate price can be determined when extensive information is searched and compared with different methods.
    What are the relevant safety considerations for 2,5-dichloro-1H-imidazolo [4,5-b] pyridine?
    2% 2C5-difluoro-1H-indolo [4,5-b] pyridine is a special organic compound, which requires detailed attention due to its safety precautions.
    This compound may have certain toxicity. The presence of fluorine atoms in its chemical structure may affect human physiology. If ingested orally, it may cause gastrointestinal discomfort, such as nausea, vomiting, abdominal pain, etc. If it is exposed to the skin, it may cause skin irritation or allergic reactions, resulting in redness, swelling, and itching. If it inhales its dust or volatile gases, or irritates the respiratory tract, causing cough, asthma, etc.
    Furthermore, its chemical activity should also be paid attention to. Under certain conditions, or react with other chemical substances. When storing, keep away from strong oxidizing agents, strong acids, strong bases, etc., to prevent violent reactions and even the risk of fire or explosion. During operation, it should also be avoided from contact with active metals, which may trigger uncontrollable reactions.
    In addition, the environmental impact of this compound cannot be ignored. If it is released at will, it may cause pollution to soil and water sources. Due to its stable chemical properties, or long-term retention in the environment, it affects the ecological balance.
    Therefore, it is necessary to strictly follow safety procedures when handling 2% 2C5-difluoro-1H-indolo [4,5-b] pyridine. Operators need to wear appropriate protective equipment, such as protective gloves, protective glasses, gas masks, etc. After the operation is completed, properly dispose of the remaining compounds and related waste and must not be discarded at will. Only in this way can the safety of personnel and the environment be ensured.