2 5 Dibromopyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,5-dibromopyridine-3-carboxylic acid

    Specifications

    HS Code

    382249

    Chemical Formula C6H3Br2NO2
    Molar Mass 278.90 g/mol
    Appearance Solid (presumably, based on common nature of such compounds)
    Physical State At Room Temp Solid
    Solubility In Water Limited (due to non - polar aromatic part and polar carboxylic group)
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF

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    General Information
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    Frequently Asked Questions

    As a leading 2,5-dibromopyridine-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-dibromopyridine-3-carboxylic acid?
    2% 2C5-dihydroxybenzene-3-carboxylic acid, this substance is widely used in the pharmacology of Dan formula. Its primary use is to be used as medicine to help people.
    Looking at its properties, it has the ability to adjust qi and blood. Personal qi and blood are expensive to circulate. If qi and blood are not smooth, various diseases are prone to occur. This medicine can help qi and blood flow around, nourish the viscera, and clear the meridians. For example, people's limbs are numb, their complexion is yellow, and they are mostly blocked by qi and blood or deficient. Using this medicine to adjust it can make qi and blood flow smoothly, numbness and self-removal, and their complexion turns moist.
    Furthermore, it is also effective in clearing heat and reducing fire. The accumulation of heat in the body is easy to disturb the mind and mind, causing upset, sores on the mouth and tongue, red eyes, swelling and pain, etc. 2% 2C5-dihydroxybenzene-3-carboxylic acid can clear away the inherent heat evil, make the heat go away and feel safe, and all diseases are slowed down. Just like the hot summer heat, with a cooling agent, relieve the pain of dryness and heat.
    In addition, it also has the power of recuperating the viscera. It can benefit the spleen and stomach, and help the movement. The spleen and stomach are the foundation of the day after tomorrow, and the source of qi and blood biochemistry. If the spleen and stomach are unhealthy, the diet will not melt, and the source of qi and blood will be depleted. This medicine can help the spleen and stomach to transport the essence of water and valley, so that the qi and blood It can also nourish the liver and kidney, which are homologous to the liver and kidney. If the liver and kidney are deficient, the waist and knees will be sore and dizzy. This product nourishes the yin of the liver and kidney, which can slow down such deficiency.
    However, the way to use medicine lies in accuracy. The dosage must be considered according to the patient's deficiency, cold and heat, and physical strength. Use it properly, such as a good general to use the army, and the medicine will cure the disease; if used improperly, it will be like a knife and an axe, and the body will be injured. Doctors should carefully examine the condition and treat it through syndrome differentiation, so that this medicine can exert its maximum effect and relieve the diseases of the common people.
    What are the synthesis methods of 2,5-dibromopyridine-3-carboxylic acid?
    The synthesis of 2% 2C5-diethoxybenzene-3-carboxylic acid can be achieved by the following methods:
    First, a suitable benzene derivative is used as the starting material, and a halogen atom is introduced into the benzene ring at a specific position through a halogenation reaction. Subsequently, the basic structure of 2,5-diethoxybenzene is constructed by substituting the halogen with an ethoxy group through a nucleophilic substitution reaction. After that, a suitable carboxylation reagent, such as carbon dioxide or its equivalent, is used to react with the obtained 2,5-diethoxybenzene under specific conditions to introduce a carboxyl group at the specified position of the benzene ring, thereby obtaining 2,5-diethoxybenzene-3-carboxylic acid.
    Second, benzene derivatives containing carboxyl groups can also be prepared first, and then the carboxyl groups can be selectively protected to carry out ethoxylation reactions. Select suitable ethoxylation reagents, and under appropriate catalyst and reaction conditions, connect ethoxy groups to specific positions of the benzene ring. Finally, remove the protective group of the carboxyl group to obtain the target product. This approach requires precise control of the protection and deprotection steps to ensure the selectivity and yield of the reaction.
    Third, using aryl boric acid or its ester compounds as raw materials, and halogenated ethoxylbenzene derivatives, under the catalyst of transition metals, through Suzuki coupling reaction, construct 2,5-diethoxylbenzene structures. Subsequently, the specific group on the benzene ring is converted into a carboxyl group by a suitable method to achieve the synthesis of 2,5-diethoxybenzene-3-carboxylic acid. This method relies on the high efficiency and selectivity of transition metal catalysts to achieve precise coupling reactions.
    Each synthesis method has its own advantages and disadvantages. According to the availability of raw materials, the difficulty of controlling reaction conditions, the requirements of yield and purity, and many other factors, the most suitable synthesis path should be carefully selected to obtain 2,5-diethoxybenzene-3-carboxylic acid efficiently and with high quality.
    What are the physical properties of 2,5-dibromopyridine-3-carboxylic acid?
    2% 2C5-dibromohexyl-3-alkynic acid is an organic compound. Its physical properties are as follows:
    Above the appearance properties, at room temperature and pressure, this substance mostly presents a colorless to pale yellow liquid state. Because the molecule contains specific functional groups such as carbon-carbon triple bonds and bromine atoms, the electron cloud distribution and interaction of these functional groups create this appearance. However, it should be noted that if it contains impurities, the appearance may change, such as color deepening.
    In terms of melting point and boiling point, the melting point will vary due to the influence of intermolecular forces, relative molecular mass and molecular structure. The presence of alkyne bonds and bromine atoms in the molecule enhances the intermolecular forces, and the melting point is slightly higher than that of ordinary alkanes. The boiling point increases due to the increase of the intermolecular force and the increase of the relative molecular weight, and the specific value will vary depending on the precise structure and test conditions.
    In terms of solubility, the substance is slightly soluble in water. Due to its organic structure, it has a certain hydrophobicity, while there is a strong hydrogen bond between water molecules, and the interaction between the two is weak, so it is difficult to dissolve. But it is soluble in many organic solvents, such as common ethanol, ether, chloroform, etc. Because its molecular structure is similar to that of organic solvents, van der Waals forces and other interactions can be formed between molecules, which is conducive to dissolution.
    In terms of density, due to the large relative atomic weight of bromine atoms in the molecule, its density is higher than that of water. The heavy atom properties of bromine atoms increase the mass of the substance per unit volume, causing it to sink to the bottom when mixed with less dense liquids such as water.
    Volatility is relatively low due to strong intermolecular forces. The alkyne bonds between molecules and the interactions caused by bromine atoms require higher energy for molecules to break away from the liquid surface and enter the gas phase, so the volatilization rate is slower at room temperature.
    What is the price range of 2,5-dibromopyridine-3-carboxylic acid in the market?
    The price of 2% 2C5-dibromothiophene-3-carboxylic acid in the market often varies depending on the quality and market conditions. Its price may range from tens to hundreds of gold per kilogram. If the quality is good and the market is prosperous, the price will tend to be higher; if the quality is flat and the market is more, the price will tend to be lower.
    The production system of this product is related to its price. If the system is refined and the production is wide, the cost may be reduced, and the price will also be reduced. In addition, the demand of the market is the main reason for the price. If it is used in various industries, such as medicine and chemical manufacturing, if you ask for more, the price will rise; if you ask for less and supply more, the price will fall. < Br >
    And its price is also affected by the time and place. At a time and place, due to transportation, taxes and other feelings, the price varies. Therefore, if you want to know the exact price, you should consult the merchants and the family of the market analysis to get a near-real number.
    What are the storage conditions for 2,5-dibromopyridine-3-carboxylic acid?
    2% 2C5-dihydroxybenzoic acid-3-methoxybenzoic acid, this substance should be placed in a cool, dry and well-ventilated place, and away from fire and heat sources. Because of its certain chemical activity, it is afraid of qualitative change when exposed to heat or humid environment, which will damage its effectiveness.
    This medicine should also be avoided from mixing with strong oxidants, strong acids, strong bases and other substances. Strong oxidants are highly oxidizing, or react violently with this product, causing danger; strong acids and strong bases are highly corrosive, which will also damage their chemical structure and cause their properties to change.
    When storing, it needs to be contained in a sealed container to prevent moisture intrusion and reaction with air components. The choice of container material should also be cautious. Glass or specific plastic materials may be suitable because of their good chemical stability.
    In addition, a special storage area should be set up to prevent misuse with other chemicals. And the storage place should be inspected regularly to see if there is any leakage, deterioration, etc. If there is any abnormality, it should be properly disposed of quickly to preserve the safety of storage.