2 5 Bis 4 Hydroxyphenyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2,5-bis(4-hydroxyphenyl)pyridine

    Specifications

    HS Code

    878935

    Chemical Formula C17H13NO2
    Molecular Weight 263.29 g/mol
    Appearance Solid (usually white to off - white powder)
    Melting Point Typically in a certain range (needs specific experimental data)
    Boiling Point Requires experimental determination
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, DMSO
    Pka Value Related to its acidic or basic nature (experimental data needed)
    Density Needs experimental determination
    Stability Stable under normal conditions, may decompose under extreme heat or in the presence of strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2,5-bis(4-hydroxyphenyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-bis (4-hydroxyphenyl) pyridine?
    2%2C5-bis%284-hydroxyphenyl%29pyridine is 2,5-bis (4-hydroxyphenyl) pyridine, which has a wide range of uses. In the field of material chemistry, it is often used as a key intermediate in organic synthesis. With this raw material, through clever chemical reaction, polymer materials with specific properties can be prepared, such as conjugated polymers with excellent photoelectric properties. These polymers shine in the manufacture of optoelectronic devices such as organic Light Emitting Diode (OLED) and solar cells, which can improve the luminous efficiency and stability of the device.
    In the field of pharmaceutical chemistry, 2,5-bis (4-hydroxyphenyl) pyridine is also of great significance. Due to its unique chemical structure, it may interact well with specific targets in organisms, so it is often the parent nucleus structure optimized by lead compounds. After structural modification and modification, it is expected to develop new therapeutic drugs to overcome various diseases.
    In addition, in the field of coordination chemistry, 2,5-bis (4-hydroxyphenyl) pyridine can be used as an excellent ligand to coordinate with metal ions by virtue of its pyridine ring and hydroxyl group. The formed metal complexes, or with novel structures and special physical and chemical properties, show potential application value in catalysis, molecular recognition and preparation of magnetic materials. In short, 2,5-bis (4-hydroxyphenyl) pyridine plays an indispensable role in many scientific fields due to its various uses.
    What are the physical properties of 2,5-bis (4-hydroxyphenyl) pyridine
    2%2C5-bis%284-hydroxyphenyl%29pyridine, that is, 2,5-bis (4-hydroxyphenyl) pyridine, the physical properties of this substance are particularly important, and it is relevant to its application in various fields.
    Its appearance, under normal conditions, is mostly white to light yellow crystalline powder, which is the first characteristic observed by the eye. Its color and morphology are quite useful in preliminary identification and determination of purity.
    When talking about the melting point, it is about 220-225 ℃. Melting point is an inherent property of the substance, and accurate melting point data can provide a key basis for purity identification. If the melting point of the sample deviates from this range, it may suggest that its purity is not good, mixed with impurities.
    Solubility is also an important property. In common organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it exhibits good solubility and can be uniformly dispersed to form a solution. However, in water, the solubility is relatively limited. This difference in solubility needs to be carefully considered during the preparation of solutions, separation and purification, and selection of reaction media.
    In addition, although there is no exact and widely disseminated data, its density can be inferred from related similar structural compounds, which is roughly in the range of 1.2-1.3 g/³ cm. Density information has certain reference value in practical operations such as mass and volume conversion, material ratio, etc. The physical properties of 2,5-bis (4-hydroxyphenyl) pyridine, such as appearance, melting point, solubility, and approximate density, are essential basic information for scientific research, industrial production, and many other aspects. In-depth understanding of it will help to make better use of this substance.
    What is the chemical synthesis method of 2,5-bis (4-hydroxyphenyl) pyridine
    To prepare 2,5-bis (4-hydroxyphenyl) pyridine, follow the following ancient method.
    First take an appropriate amount of 4-hydroxybenzaldehyde and malononitrile and place them in a clean reactor. Use absolute ethanol as a solvent and add an appropriate amount of piperidine as a catalyst. This piperidine can promote the reaction. The reaction system is heated to an appropriate temperature, generally about 60-80 degrees Celsius, and stirred continuously, so that the reactants are fully contacted and reacted. In this process, 4-hydroxybenzaldehyde and malonitrile are catalyzed by piperidine, and the condensation reaction gradually occurs.
    When the reaction reaches a certain level, the reaction progress can be seen, and the thin layer chromatography is used to monitor it. After the reaction is basically complete, stop heating. The reaction mixture is cooled to room temperature, followed by reduced pressure distillation to remove the ethanol solvent. After obtaining the crude product, a suitable organic solvent, such as a mixed solvent of ethyl acetate and petroleum ether, is used for recrystallization. After multiple recrystallization, a pure 2,5-bis (4-hydroxyphenyl) pyridine product can be obtained.
    When operating, be sure to pay attention to the conditions of each step. The purity of the solvent, the amount of catalyst, the reaction temperature and time, etc., all have a significant impact on the yield and purity of the product. In this way, the ideal result can be obtained.
    In which fields is 2,5-bis (4-hydroxyphenyl) pyridine used?
    2% 2C5 - bis% 284 - hydroxyphenyl%29pyridine is 2,5 - bis (4 - hydroxyphenyl) pyridine, which is useful in materials science, medicinal chemistry, optoelectronic devices and many other fields.
    In the field of materials science, due to its unique molecular structure and electronic properties, it can be used as a monomer for high-performance polymer synthesis. Through clever polymerization, polymer materials with excellent thermal stability, mechanical properties and electrical properties can be prepared. These materials can be used to manufacture high-performance components in industries such as aerospace and automotive manufacturing, which require strict material properties, and can contribute to the development of related industries.
    In the field of medicinal chemistry, its special structure confers potential biological activity. Scientists can develop new drugs through modification and modification. For example, studies have found that it has a certain affinity for specific enzymes or receptors, or can become a lead compound for the treatment of certain diseases, opening up new paths for innovative drug research and development.
    In the field of optoelectronic devices, 2,5-bis (4-hydroxyphenyl) pyridine exhibits good optical properties and can act as a light-emitting layer material for organic Light Emitting Diodes (OLEDs). It can achieve high-efficiency electroluminescence, improve the luminous efficiency and stability of OLEDs, and make display screens with better image quality and longer lifespan. It is widely used in display devices such as mobile phones and TVs, promoting continuous innovation in display technology.
    To sum up, 2,5-bis (4-hydroxyphenyl) pyridine, with its unique structure and properties, plays an important role in many fields, contributes to the progress of various industries, and has broad prospects.
    What is the market outlook for 2,5-bis (4-hydroxyphenyl) pyridine?
    2% 2C5 - bis% 284 - hydroxyphenyl%29pyridine is 2,5 - bis (4 - hydroxyphenyl) pyridine. The market prospect of this compound depends on many factors.
    First talk about its application field. This compound is often a key raw material for the preparation of high-performance organic optoelectronic materials in the field of materials science. In today's era, there is an increasing demand for organic optoelectronic materials, such as organic Light Emitting Diode (OLED) displays, which are widely used in mobile phones, televisions and other electronic products. Because it can endow devices with excellent luminous performance and high stability, it has a good prospect in this field. Furthermore, in the field of medicinal chemistry, it may have unique biological activities, after rational modification and research and development, or it can become a new type of drug to treat specific diseases, which is also a major addressable market direction.
    However, looking at its marketing activities, there are also challenges. The complexity and cost of the synthesis process are key constraints. If the synthesis process is cumbersome and costly, it will limit its large-scale production and application. And the market competition is quite fierce, similar or alternative materials continue to emerge. In order to take the lead in the market, it is necessary to continuously improve technology and improve product quality.
    Overall, the market prospect of 2,5-bis (4-hydroxyphenyl) pyridine has potential, but it also needs to deal with many challenges. With time, researchers will make unremitting efforts to optimize the synthesis process and expand the scope of application, or they will be able to shine in the market and gain a broad development space.