2 4 Trifluoromethoxy Phenyl Pyridine 5 Methanol
pyridine pyrrole pyrazine piperidine piperazine

2-(4-(Trifluoromethoxy)phenyl)pyridine-5-methanol

    Specifications

    HS Code

    460543

    Chemical Formula C13H10F3NO2
    Molecular Weight 271.22
    Appearance Solid (predicted)
    Boiling Point 352.3 °C at 760 mmHg (predicted)
    Melting Point 83 - 87 °C
    Flash Point 166.9 °C (predicted)
    Density 1.352 g/cm³ (predicted)
    Solubility Soluble in organic solvents like DMSO, methanol (predicted)
    Logp 2.79 (predicted)
    Pka 14.15±0.46 (predicted)

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    What are the physical properties of 2- (4- (trifluoromethoxy) phenyl) pyridine-5-methanol
    5-Ethylheptane is an organic compound and belongs to the category of alkanes. It has the following physical properties:
    1. ** Physical state and appearance **: At room temperature and pressure, it is mostly a colorless and transparent liquid. This characteristic is derived from the weak van der Waals force between alkanes. Under this condition, the molecular spacing is suitable and it presents a liquid state. Its colorless and transparent appearance makes it easy to observe and operate in many experimental and industrial application scenarios.
    2. ** Boiling point **: Generally speaking, the boiling point gradually increases as the number of carbon atoms in the alkane molecule increases. 5-Ethylheptane molecules contain ten carbon atoms, and their boiling points are in a specific range, roughly around 170-180 ° C. This is due to the increase in the number of carbon atoms and the increase in the force between molecules, which requires more energy to make the molecules break free from each other and boil.
    3. ** Melting point **: The melting point of 5-ethylheptane is relatively low, about -50 ° C. This is due to the jagged chain structure of alkane molecules, the arrangement of molecules is not tightly ordered, and the lattice energy is relatively small, so less energy is required to destroy the lattice and melt it.
    4. ** Density **: The density is less than that of water, about 0.75 - 0.78g/cm ³. This is because the carbon and hydrogen atoms in the alkane molecule are relatively small in atomic weight, and the intermolecular spacing is large, resulting in the overall density being lower than that of water. This property makes 5-ethylheptane float on the water surface when mixed with water.
    5. ** Solubility **: 5-ethylheptane is insoluble in water, but easily soluble in organic solvents such as ethanol, ether, benzene, etc. This is because water is a polar molecule, while 5-ethylheptane is a non-polar molecule. According to the principle of "similarity miscibility", non-polar 5-ethylheptane is insoluble in polar water, while it is easy to dissolve in non-polar or weakly polar organic solvents.
    What are the chemical properties of 2- (4- (trifluoromethoxy) phenyl) pyridine-5-methanol
    5-Ethylheptane is an organic compound and belongs to the alkane class. Its chemical properties are as follows:
    First, it has stability. Under normal conditions, 5-ethylheptane is stable and generally does not react with strong acids, strong bases and strong oxidants. This is because the carbon-carbon single bond and carbon-hydrogen single bond energy of alkanes are relatively high, and the structure is stable. As "Tiangong Kaiwu" said, "Things have their own properties, and often are safe", the stability of 5-ethylheptane is its inherent property.
    Second, combustion reactions can occur. 5-ethylheptane can burn violently in sufficient oxygen to generate carbon dioxide and water, and release a large amount of heat energy. The chemical equation for its combustion is roughly: $C_ {10} H_ {22} +\ frac {31} {2} O_ {2}\ stackrel {ignited }{=\!=\!=} 10CO_ {2} + 11H_ {2} O $. This reaction is similar to the description of fuel combustion in Tiangong Kaiju, which can produce light and heat and can be used as energy.
    Third, a substitution reaction can be carried out. Under light or high temperature conditions, hydrogen atoms in 5-ethylheptane can be replaced by halogen atoms. For example, when reacted with chlorine gas under light, chlorinated hydrocarbons and hydrogen chloride will be formed. This process is similar to the interaction and component replacement scenarios described in Tiangong Kaiju.
    Fourth, thermal cracking reaction. In high temperature and anoxic or anoxic environment, the carbon-carbon bond in 5-ethylheptane molecules will break, forming small molecules of alkanes, olefins, etc. This is like the record in "Tiangong Kaiwu" of substances producing new substances through high temperature changes, showing the characteristics of 5-ethylheptane's structure changing and forming new compounds under specific conditions.
    What are the synthesis methods of 2- (4- (trifluoromethoxy) phenyl) pyridine-5-methanol?
    To prepare 2 - (4- (triethoxy) benzyl) -5 -ethylpyrimidine, the synthesis method is as follows:
    The first is the reaction of benzyl halide and triethoxy compound. Take appropriate benzyl halide, such as benzyl chloride or benzyl bromide, and triethoxy compound in a suitable solvent, such as toluene, dichloromethane, etc., add appropriate base, such as potassium carbonate, sodium carbonate, etc., heat and stir, and after nucleophilic substitution reaction, 4 - (triethoxy) benzyl intermediate can be obtained. This step requires temperature control and time control, pay attention to the reaction process to ensure complete reaction, and pay attention to the drying of the solvent and the anhydrous environment of the reaction system to prevent side reactions. < Br >
    The second is the construction of the pyrimidine ring. The obtained 4- (triethoxy) benzyl intermediate is reacted with the pyrimidine synthesizer containing ethyl group under specific conditions. The reaction is often heated in anhydrous organic solvents such as tetrahydrofuran, N, N-dimethylformamide, etc. with suitable bases as catalysts, such as sodium hydride and potassium tert-butoxide. During the reaction, the activity check point of the pyrimidine synthesizer is cyclized and condensed with the 4- (triethoxy) benzyl intermediate to construct the pyrimidine ring structure, and the target product is 2 - (4- (triethoxy) benzyl) -5 -ethylpyrimidine. < Br >
    After the reaction is completed, the product needs to be separated and purified. The reaction solution can be extracted by extraction method with a suitable organic solvent. After separation, the organic phase is dried with a desiccant such as anhydrous sodium sulfate to remove water. Then purified by column chromatography, select suitable silica gel and eluent, and obtain pure 2- (4- (triethoxy) benzyl) -5 -ethylpyrimidine according to the polarity difference between the product and the impurity. Each step of the reaction requires strict control of conditions to improve the yield and purity of the product.
    In which fields is 2- (4- (trifluoromethoxy) phenyl) pyridine-5-methanol used?
    "Tiangong Kaiwu" has a saying: "Where dipentyl (2 -) is not juxtaposed with pentyl (5 -), if the two are mixed, it will change and become unusable. As for tripentyl (3 -), among them, pentyl (3-hydroxypropyl) is common, but there are also specific ones."
    This word "2- (4- (triethoxy) phenyl) -5-ethylpyridine", in this compound, the 2-position and the 5-position of 5-ethylpyridine each have their own specific structures and properties. 2 - (4- (triethoxy) phenyl) moiety, triethoxy is connected to phenyl, and the presence of ethoxy affects the electron cloud distribution of phenyl, which in turn affects the chemical activity of the whole molecule. The 5-position of 5-ethylpyridine is connected to ethyl, and ethyl is the power supply group, which can change the electron density of the pyridine ring and affect its reaction check point and reactivity.
    Its application is often found in the field of organic synthesis. It can be used as a key intermediate to participate in the construction of more complex organic molecular structures. Due to its unique molecular framework and electronic properties, it can play an important role in catalytic reactions, or complex with metal ions as a ligand, which affects the selectivity and activity of metal catalytic reactions. In the field of materials science, based on this compound, new functional materials can be designed and synthesized, such as materials with specific optoelectronic properties, for the preparation of optoelectronic devices. Its molecular structure endows materials with unique electronic transition characteristics, or in the field of molecular recognition, its specific structure can be used to interact with other molecules to realize the identification and detection of specific molecules.
    What is the market outlook for 2- (4- (trifluoromethoxy) phenyl) pyridine-5-methanol?
    "Tianwen Creation" once said that the market situation is changeable, just like the unpredictable celestial phenomenon, the rise and fall of business, just like the impermanence of the world. Today's discussion of the market prospect of 2- (4- (Three Gorges Acetyl) Benzyl) Pyridine-5 -Acetylpyridine also needs to be analyzed in detail from various factors.
    Watching this product, the situation of its industry is the primary consideration. At present, the chemical industry is developing rapidly, and fine chemicals are emerging. The demand for such compounds with specific chemical structures and functions is gradually rising. This is the trend of the general environment, such as sailing along the water, which is beneficial to the expansion of the product market.
    Furthermore, its own characteristics and application scope are related to the market prospect. If 2- (4- (Three Gorges Acetyl) Benzyl) Pyridine-5-Acetylpyridine can demonstrate unique performance and application value in key fields such as pharmaceutical synthesis and material science, it will surely attract the attention of many manufacturers, and the demand will surge accordingly. For example, if Liangju meets Bole, it will be able to develop, and the market will also open up.
    However, market competition cannot be ignored. If there are many competitors in the same industry launching similar products, and they have the upper hand in cost control, quality improvement, etc., it is not easy for this product to stand out. It is like being in a battle of thousands of troops, and you need exceptional ability to break through the encirclement.
    Policies and regulations also influence the market. If environmental protection policies become stricter, production processes are limited, and costs will increase; conversely, if policies encourage innovation and support the research and development and production of such new compounds, the future will be bright. This is a double-edged sword of policy, used properly, and benefits are endless.
    Overall, the market prospect of 2- (4- (Three Gorges Acetyl) Benzyl) Pyridine-5-Acetylpyridine, although there are challenges, there are also abundant opportunities. It is like seeing flowers in the fog, you need to clear the clouds and gain insight into business opportunities; it is also like walking against the current, only by forging ahead, making good use of advantages and avoiding risks can you sail away in the market wave and achieve great results.