2-(4-Morpholino)pyridine-5-boronic acid pinacol ester

2-%284-Morpholino%29pyridine-5-boronic + acid + pinacol + ester is 2- (4-morpholinyl) pyridine-5-boronic acid pinacol ester. The chemical structure of this compound is explained in detail.
Its core structure is a pyridine ring, and the pyridine is a six-membered nitrogen-containing heterocyclic ring with aromatic properties. At the second position of the pyridine ring, a 4-morpholine group is connected. The morpholine group is a five-membered heterocyclic ring containing nitrogen and oxygen, and the nitrogen atom is connected to the carbon at the second position of the pyridine ring, giving the molecule a specific electronic effect and spatial structure.
And at the 5th position of the pyridine ring, the boric acid pinacol ester group is connected. The boric acid pinacol ester structure is formed by the condensation of boric acid and pinacol, in which the boron atom is connected to the 5-position carbon of the pyridine ring, and the boron atom is then connected to two oxygen atoms. The two oxygen atoms are respectively from pinacol, which has a specific carbon skeleton structure. The boric acid pinacol ester group thus formed adds unique reactivity and properties to the molecule.
In summary, the chemical structure of 2- (4-morpholinyl) pyridine-5-boronic acid pinacol ester is composed of a pyridine ring as the core, which connects 4-morpholinyl group and boronic acid pinacol ester group at a specific position. This structure determines its physicochemical properties and the characteristics of participating in chemical reactions.

2-% (4-morpholinyl) pyridine-5-boronic acid pinacol ester, which has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Because of its unique chemical structure and activity, it can participate in various reactions and help build complex organic molecular structures.
In the field of pharmaceutical chemistry, its use cannot be ignored. In many drug development processes, the introduction of this compound structure fragment can optimize the physicochemical properties, biological activities and pharmacokinetic properties of drug molecules. For example, when designing new targeted anticancer drugs, it can be used to modify drug molecules, enhance the affinity and selectivity of drugs with specific targets, improve efficacy and reduce side effects.
In the field of materials science, it also has a place to be applied. Or it can participate in the preparation of materials with special photoelectric properties, such as organic Light Emitting Diode (OLED) materials. With its unique electronic structure, it endows the material with novel electrical and optical properties, providing the possibility for the development of high-performance new materials.
In the field of catalytic chemistry, this compound can be used as a ligand to coordinate with metal ions to form a high-efficiency catalyst. Its structural flexibility and electronic effect can precisely regulate the activity and selectivity of the catalyst, and it is widely used in various catalytic reactions to improve the reaction efficiency and product purity. In summary, 2% (4-morpholinyl) pyridine-5-boronic acid pinacol esters play an important role in many fields, promoting the continuous development and progress of various fields.

2-%284-Morpholino%29pyridine-5-boronic+acid+pinacol+ester is 2- (4-morpholinyl) pyridine-5-boronic acid pinacol ester, and its synthesis method is as follows:
The starting material selects the compound containing the pyridine structure and the reagent containing the morpholine group, and first introduces the morpholine group at a specific position on the pyridine ring. For example, halogenated pyridine and morpholine can be connected to the morpholine group by nucleophilic substitution reaction under the action of suitable bases and catalysts. Bases such as potassium carbonate, catalysts such as cuprous iodide are combined with corresponding ligands, and the reaction is heated and stirred in a suitable organic solvent such as N, N-dimethylformamide (DMF). This step can obtain key intermediates.
Subsequently, the resulting intermediate is introduced into the boronic acid pinacol ester. Biboronic acid pinacol ester (B2pin2) is often used, catalyzed by palladium catalysts such as tetra (triphenylphosphine) palladium (Pd (PPh)), and reacted in toluene and other organic solvents in the presence of bases such as potassium acetate. During the reaction, nitrogen protection is required, heated to a certain temperature, and after a palladium-catalyzed coupling process, the boronic acid pinacol ester group is attached to the appropriate position of the pyridine ring to finally obtain 2- (4-morpholino) pyridine-5-boronic acid pinacol ester. After each step of the reaction, the product needs to be purified by extraction, column chromatography and other separation methods to improve the purity.

2-%284-Morpholino%29pyridine-5-boronic acid pinacol ester is an important compound in organic synthesis. Its physical and chemical properties are unique and have a great impact on organic synthesis reactions.
In terms of its physical properties, under normal conditions, this compound is mostly solid and has a specific melting point. Melting point is a key indicator for identification and purity determination. Accurate measurement and recording of the melting point of this substance can help chemists accurately control the reaction conditions.
Looking at its solubility, it shows good solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). This property allows it to fully contact with other reactants in the organic synthesis reaction system and effectively promote the reaction. In dichloromethane, it can quickly dissolve and disperse uniformly, creating a good environment for the reaction.
In terms of chemical properties, the molecular structure contains boron ester groups and pyridine rings, and boron ester groups are active, and often play a key role in many important organic reactions such as the Suzuki-Miyaura coupling reaction. In the Suzuki-Miyaura coupling reaction, boron ester groups and halogenated aromatics or olefins can efficiently form carbon-carbon bonds under the action of palladium catalyst and base, providing a powerful means for constructing complex organic molecular structures.
Pyridine rings are basic and can react with acids to form corresponding salts. This alkaline property also affects its chemical behavior in the reaction system, which can participate in the acid-base catalyzed reaction process and expand its application range in the field of organic synthesis.
The physicochemical properties of 2-%284-Morpholino%29pyridine-5-boronic acid pinacol ester provide rich possibilities and solid foundations for organic synthesis chemists to design and implement various complex organic synthesis reactions.

I look at your question, but I am inquiring about the price range of 2- (4-morpholinyl) pyridine-5-boronic acid pinacol ester in the market. However, the price of this compound often changes for a variety of reasons, and it is difficult to determine the exact number.
First, the source of supply is different, and the price is also different. If it comes from a well-known and large-scale factory, its production process is mature, quality control is strict, and the product purity is high, the price may be high; while the price produced by a small factory is low or low, the quality cannot be fully trusted.
Second, the amount of purchase has a great impact on the price. If a large number of purchases are made, merchants often give discounts due to small profits but quick turnover, and the unit price is lower; if only a small amount is purchased, the unit price will be higher.
Third, the market supply and demand situation also affects its price. If the demand for this product is strong and the supply is limited, the price will rise; on the contrary, if the supply exceeds the demand, the price may fall.
According to the past market situation, the price per gram, when purchasing in small quantities, may range from tens of yuan to hundreds of yuan; if purchasing in large quantities, it may be reduced to a few yuan to tens of yuan per gram. However, this is only a rough estimate, and the actual price should be determined according to the current market changes. For accurate pricing, please consult chemical raw material suppliers for real-time quotations.