2-(4-Methylphenyl)-6-methylimidazole[1,2-a]-pyridine-3-acetic Acid

2-% 284 - Methylphenyl% 29 - 6 - methylimidazole%5B1%2C2 - a% 5Dpyridine - 3 - acetic Acid is 2 - (4 - methylphenyl) - 6 - methylimidazolo [1,2 - a] pyridine - 3 - acetic acid, which has a wide range of uses.
In the field of medicine, it is often a key intermediate for the creation of new drugs. Because of its unique chemical structure, it can be cleverly linked with other compounds through specific chemical reactions to construct drug molecules with specific physiological activities. For example, in the development of targeted drugs for specific diseases, the structure of this compound can be modified and modified to precisely act on the target of diseased cells and inhibit the progression of the disease, so it has a role in the development of anti-cancer, anti-inflammatory and neurological diseases.
In the field of materials science, it may be used to prepare materials with unique functions. With its own chemical properties, it may be able to participate in the material synthesis process, endowing materials with special properties such as optics and electricity. For example, when synthesizing some organic luminescent materials, the introduction of this compound structure may improve the luminous efficiency and stability of the material, making the material useful in display technology, lighting and other fields.
In the field of chemical research, it is also an important chemical reagent. Chemists often use it as a starting material to carry out research on various organic synthesis reactions, explore novel synthesis methods and reaction paths, and help the development of organic chemistry. Because of its complex structure and reactive activity check point, it can provide diverse possibilities for organic synthesis chemistry research and promote the innovation and progress of organic synthesis methodologies.

2-%284-Methylphenyl%29-6-methylimidazole%5B1%2C2-a%5Dpyridine-3-acetic Acid is 2- (4-methylphenyl) -6-methylimidazolo [1,2-a] pyridine-3-acetic acid, and its synthesis method is as follows:
The starting material can be selected from 4-methylacetophenone and 2-amino-3-methylpyridine. Mix 4-methylacetophenone with an appropriate amount of base, in a suitable solvent such as ethanol, heat and stir, so that the α-hydrogen of 4-methylacetophenone is captured by the base to form a carboanion. Subsequently, 2-amino-3-methylpyridine is added, and a nucleophilic addition reaction occurs to generate an intermediate. This intermediate is further cyclized and dehydrated, and the intramolecular dehydration can be promoted by heating or adding a dehydrating agent such as concentrated sulfuric acid to form an imidazolo [1,2-a] pyridine structure.
Next, the obtained imidazolo [1,2-a] pyridine derivative is carboxylated. Carbon dioxide is used as a carboxyl source to react with the derivative in the presence of a metal catalyst such as palladium catalyst to introduce an acetic acid group at the 3-position of the pyridine ring. The reaction needs to be carried out under appropriate temperature and pressure conditions. Generally, the temperature is controlled at tens of degrees Celsius, and the pressure is slightly higher than normal pressure.
After the reaction is completed, the product is separated and purified. First, most of the solvent is removed by reduced pressure distillation, and then by column chromatography, silica gel is used as the stationary phase, and a suitable eluent such as a mixed solvent of petroleum ether and ethyl acetate is eluted to collect the fraction containing the target product. Finally, crystallization treatment is performed to obtain pure 2- (4-methylphenyl) -6-methylimidazolo [1,2-a] pyridine-3-acetic acid.

2-% 284 - Methylphenyl% 29 - 6 - methylimidazole%5B1%2C2 - a% 5Dpyridine - 3 - acetic Acid, this is an organic compound, often translated as 2 - (4 - methylphenyl) - 6 - methylimidazolo [1,2 - a] pyridine - 3 - acetic acid. Its physicochemical properties are quite important and related to many applications of this compound.
Looking at its physical properties, under normal circumstances, it may be a solid, because many organic compounds with such structures are in a solid state. As for the color, it may vary depending on the purity. When it is of high purity, it may be a white crystalline powder. If it contains impurities, the color may change. The melting point is also a key physical property, and its specific value depends on factors such as intermolecular forces. The chemical bonds and group interactions within the molecule cause the phase transition of the molecule at a specific temperature. The melting point of this compound may be within a certain range, and the exact value needs to be determined experimentally.
When it comes to chemical properties, its structure contains a variety of functional groups, so it has rich chemical reactivity. The molecule contains carboxyl groups, which are acidic and can neutralize with bases to form corresponding carboxylate. Carboxyl groups can also participate in esterification reactions, and react with alcohols under specific conditions through catalysts to form ester compounds. At the same time, the structure of imidazolopyridine gives it a certain alkalinity and can react with acids to form salts. Aromatic ring structures, such as 4-methylphenyl, can undergo electrophilic substitution reactions, such as halogenation, nitration, sulfonation, etc. Under appropriate conditions, corresponding substituents can be introduced into the aromatic ring to expand its chemical derivatization. In addition, the stability of this compound is also related to its chemical properties, and its stability varies under different environmental conditions, such as temperature, light, and pH. High temperature or strong light irradiation, or its structure changes, affect its chemical properties and application properties.

2-%284-Methylphenyl%29-6-methylimidazole%5B1%2C2-a%5Dpyridine-3-acetic Acid, this is a specific chemical substance. However, on the market, its price range is quite difficult to determine directly.
Because the price of chemical reagents is often affected by many factors. First, the different manufacturers will lead to price differences. Well-known large factories, because of their exquisite production technology and excellent product purity, the price may be higher; while some small manufacturers, in order to seek market share, the price may be more affordable. Second, the purity of the product is also the key. High purity, high preparation cost, the price is not low; lower purity, the price is relatively cheap, but only suitable for some scenes with low requirements. Third, the purchase volume also affects the price. When purchasing in bulk, due to the scale effect, the manufacturer may give a certain discount, and the unit price will be reduced; if only a small amount is purchased, the unit price is often higher. Fourth, the market supply and demand relationship also affects the price. If the demand is strong and the supply is limited, the price will rise; on the contrary, when the supply exceeds the demand, the price will decline.
Therefore, in order to know the exact price range of this substance, it is necessary to check the chemical product trading platform in detail, or directly consult the relevant manufacturers and distributors to obtain accurate price information.

2-%284-Methylphenyl%29-6-methylimidazole%5B1%2C2-a%5Dpyridine-3-acetic Acid, which is an organic compound or has many related derivatives. Looking at its structure, it may be chemically modified to obtain phase derivatives.
In the field of chemical synthesis, or by changing the type, position and quantity of substituents, different derivatives can be created. If the methyl group on 4-methyl phenyl is replaced by a alkyl group, a halogen atom or other functional group, the physical and chemical properties of the derivative can be changed. Or modified at 6-methyl and replaced with a different hydrocarbon group, its properties will also be affected.
Looking at the main body of its imidazolopyridine-containing structure, heteroatoms can be introduced on it, or double bonds or triple bonds can be added to the ring to change the conjugate system, thereby affecting its optical and electrical properties. And its 3-acetic acid part can be esterified and amidated to carboxyl groups to obtain new derivatives. These derivatives may have different applications in the fields of medicine and materials.
If in the field of medicine, or due to structural changes, the ability to bind to specific biological targets is different from that of the original compound, or it has better biological activity and lower toxicity, it can be used as a potential drug lead compound. In the field of materials, or due to structural changes, its film-forming, electrical conductivity, fluorescence and other material properties change to meet different material requirements.