2-(4-Methoxybenzyl)-Amino Pyridine

2-% (4-methoxybenzyl) -aminopyridine is an important raw material for organic synthesis. It has a wide range of uses, first in the field of medicinal chemistry. In the process of drug development, it can act as a key intermediate to help build molecular structures with specific biological activities. Taking the synthesis of an anticancer drug as an example, this compound can participate in the construction of a specific ring system, laying the foundation for the subsequent introduction of active functional groups, thereby giving the drug the ability to precisely target cancer cells and inhibit tumor growth.
In the field of materials science, it also has important value. It can be integrated into the structure of polymer materials through specific chemical reactions. In this way, it can significantly change the electrical, optical or mechanical properties of the material. For example, when preparing organic Light Emitting Diode (OLED) materials, the introduction of this compound can optimize the luminous efficiency and stability of the material, so that the image quality of the display screen is clearer and the color is more gorgeous.
In addition, in the field of fine chemicals, it is often used to synthesize high value-added fine chemicals. For example, the preparation of some special fragrances or cosmetic additives, using its unique chemical structure, can synthesize unique fragrance substances or skin care ingredients with special effects to meet the market demand for high-end fine chemicals. Overall, with its unique structure and reactivity, 2-% (4-methoxybenzyl) -aminopyridine plays an indispensable role in many important fields, promoting the development and innovation of related industries.

2-% (4-methoxybenzyl) -aminopyridine is a kind of organic compound. According to its physical properties, it is mostly in solid form at room temperature, which makes the structure relatively stable due to the intermolecular force. Its melting and boiling point is determined by the characteristics of the groups contained in the molecular structure. The methoxy group in the molecule interacts with the pyridine ring and benzyl group, which affects the intermolecular force, and then determines the melting boiling point. Generally speaking, the melting point or in a specific range, the boiling point also matches it, and the specific value needs to be accurately determined experimentally.
In terms of solubility, the compound may have some solubility in organic solvents. Because its molecules contain lipophilic benzyl and methoxy groups, they may be well soluble in organic solvents such as ethanol and dichloromethane due to molecular interactions. However, in water, the solubility may be limited due to the fact that the overall structure is not highly hydrophilic. This solubility characteristic has a great impact on its application in various chemical reactions, as well as separation and purification steps.
From the appearance, it may be white to off-white powder, which is a common form of many such organic compounds. The powder state is conducive to its participation in various chemical reactions. Due to its large specific surface area, the reaction can be more sufficient and efficient. And color characteristics are also one of the important basis for identifying the compound. If the color deviation is large, it may suggest that its purity is questionable.
In addition, the density of 2% (4-methoxybenzyl) -aminopyridine depends on the molecular composition and structure. Compared with common organic compounds, its density may vary depending on the type, number and spatial arrangement of atoms in the molecule. This physical property is also of great significance in the chemical production and storage of the compound.

The method of synthesizing 2- (4-methoxybenzyl) -aminopyridine can follow several routes. One method is to use 4-methoxybenzyl halide and 2-aminopyridine as raw materials, so that the two are nucleophilic substitution in appropriate solvents and catalyzed by bases. Among them, the halogen atom of 4-methoxybenzyl halide has high activity, and can react with the amino group of 2-aminopyridine to form 2- (4-methoxybenzyl) -aminopyridine. The selected solvent is usually polar organic solvents such as acetonitrile, N, N-dimethylformamide, etc., because it dissolves the reactants well and the reaction is favorable. The base can be used as potassium carbonate, sodium carbonate and the like, and its function is to capture the hydrogen halide generated by the reaction, shift the reaction equilibrium to the right, and promote the reaction to be complete.
There is another way, first make 4-methoxybenzaldehyde and 2-aminopyridine condensation to obtain Schiff base intermediate, and then reduce. The carbonyl group of 4-methoxybenzaldehyde is condensed with the amino group of 2-aminopyridine to form a carbon-nitrogen double bond, which is Schiff base. Then the Schiff base is reduced with reducing agents such as sodium borohydride and lithium aluminum hydride to obtain the target product 2- (4-methoxybenzyl) -aminopyridine. The reducing power of sodium borohydride is relatively mild, and lithium aluminum hydride is stronger. The selection depends on the reaction conditions and product requirements.
Furthermore, the coupling reaction catalyzed by transition metals may be achieved. For example, palladium, copper and other metals are used as catalysts to couple 4-methoxybenzyl derivatives with 2-halopyridine in the presence of ligands and bases. The ligand can improve the activity and selectivity of the metal catalyst, and the base maintains the appropriate pH of the reaction environment. This path is also a feasible strategy for synthesizing the compound.

The price of 2 - (4 - methoxybenzyl) -aminopyridine has not been confirmed in the market. However, if you want to know the price of this product, you can search for it on the chemical raw material trading platform, such as Gade Chemical Network, Mobell Chemical Network, etc. Such platforms often gather many suppliers, and the price varies depending on the purity, quantity and supplier.
Or you can consult the chemical raw material distributor, who can tell the recent price of this product in the regular market conditions. And the chemical exhibition is also a place for price exploration. Here you can talk to the supplier directly and inquire about the price of different specifications.
In addition, the preparation process and cost also affect its price. If the preparation requires complex steps and high materials, the price may be high; if the process is simple and the raw materials are cheap, the price may be close to the people. And the market supply and demand also affect the price, and if the supply is small, the price will rise; if the supply is small, the price will be depressed. Although the exact price is not clear, following this route, the approximate price of 2 - (4 - methoxybenzyl) -aminopyridine in the market may be obtained.

2-% 284 - Methoxybenzyl% 29 - Amino Pyridine, Chinese name or 2 - (4 - methoxybenzyl) -aminopyridine. The storage conditions of this compound need to be carefully studied.
Looking at the properties of this compound, it is quite sensitive to environmental factors. The first one to bear the brunt is the temperature. It needs to be stored in a cool place, not in a high temperature place. High temperature can easily cause its structural variation, change its chemical properties, and damage its efficacy. If it is overheated, it may cause decomposition and lose its original characteristics.
Furthermore, humidity is also critical. When kept dry, keep away from moisture. Due to its hygroscopicity, if the moisture is too heavy, it is easy to absorb water vapor, causing its purity to decrease, or triggering adverse reactions such as hydrolysis, which affects the quality.
In addition, light should not be ignored. It should be stored away from light, because of light or luminescent chemical reactions, which can change the molecular structure and cause the compound to deteriorate. It should be packed in an opaque container and placed in a dark place.
When storing, also pay attention to isolation from other substances. Do not coexist with strong oxidants, strong acids, strong bases and other substances to prevent chemical reactions and damage the compound. It should be stored separately in a specific storage cabinet and marked for easy access and management. In this way, 2- (4-methoxybenzyl) -aminopyridine must be properly preserved to maintain its chemical stability and good quality.