2 4 Dimethoxypyridine
pyridine pyrrole pyrazine piperidine piperazine

2,4-dimethoxypyridine

    Specifications

    HS Code

    510341

    Chemical Formula C7H9NO2
    Molar Mass 139.152 g/mol
    Appearance Solid
    Boiling Point 204 - 205 °C
    Melting Point 35 - 37 °C
    Density 1.114 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 84.4 °C
    Pka 3.98
    Cas Number 1450-76-6

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    Frequently Asked Questions

    As a leading 2,4-dimethoxypyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2,4-dimethoxypyridine?
    2% 2C4 -dimethoxyanisole, an organic compound. It has the following physical properties:
    Viewed at room temperature, it is mostly a colorless to light yellow transparent liquid, with a pure and uniform texture, no visible impurities, or under light, it may have a weak luster, quite transparent texture.
    Smell it, emits a special aromatic smell, but this smell is more elegant than some strong fragrances, like a combination of natural and chemical subtle breath, the first smell or feel fresh, long smell is not annoying.
    Measure its boiling point, about a specific temperature range, this property is very critical in separation, purification and application. At a specific temperature, the substance changes from liquid to gaseous state, which can be used to achieve separation from other substances. < Br > Measure its melting point, which is in the corresponding low temperature range. When the ambient temperature drops below the melting point, it will condense from liquid to solid, providing a basis for consideration for its storage and transportation.
    When it comes to solubility, it shows good solubility in common organic solvents such as ethanol and ether, and can be mutually soluble with them to form a uniform solution; while in water, it has poor solubility. Due to the hydrophobic molecular structure of the substance, it has weak interaction with water molecules. This characteristic determines its behavior in different solvent systems and has a significant impact on its chemical reaction and practical application.
    From the perspective of its density, it is slightly lighter than water. If mixed with water, it will float on the water surface and present a stratification phenomenon. This characteristic is a key criterion in liquid-liquid separation operations or heterogeneous reaction systems.
    What are the chemical properties of 2,4-dimethoxypyridine?
    2% 2C4-dimethoxypyridine is an organic compound. It has various chemical properties, which are described as follows:
    First, it has strong nucleophilic substitution reactivity. Pyridine cyclic nitrogen atoms are rich in electrons and can be used as nucleophilic reagents. When encountering halogenated alkanes, nitrogen atoms attack the carbon atoms of halogenated alkanes, and the halogen atoms leave to form new carbon-nitrogen bonds to obtain N-alkylation products. This reaction is commonly used in organic synthesis to produce nitrogen-containing compounds to increase molecular complexity and functionality.
    Second, alkalinity is also an important property. The pyridine ring nitrogen atom has lone pairs of electrons, can accept protons, and is basic. In acidic media, it can combine with protons to form pyridine salts. Its alkalinity is related to the substituent on the ring, and the methyl power supply makes the electron cloud density of the pyridine ring rise, and the alkalinity is slightly stronger than that of pyridine. This alkalinity can be used to separate and purify mixtures containing 2% 2C4-dimethyloxy pyridine, or to act as alkali catalysts for specific reactions.
    Third, oxidation reaction characteristics. Pyridine rings are relatively stable, but can be oxidized under the action of strong oxidants. In case of oxidizing agents such as acids, pyridine ring nitrogen atoms can be oxidized to N-oxides. The N-oxide of 2% 2C4-dimethoxypyridine has unique reactivity in organic synthesis, and can be used as an intermediate to participate in various reactions, such as nucleophilic substitution reactions, which can change the check point and activity of the reaction to obtain special structural products.
    Fourth, the coordination ability should not be underestimated. Nitrogen atoms can coordinate with metal ions to form metal complexes. This property is widely used in the field of catalysis, such as ligand and transition metal to form complexes, catalyze organic reactions, and optimize catalyst activity and selectivity through ligand structure modulation. It is of great significance in organic synthesis, materials science and other fields.
    What are the common methods for synthesizing 2,4-dimethoxypyridine?
    2% 2C4-dimethoxypyridine. There are a number of common methods for synthesizing this compound.
    First, under appropriate reaction conditions, pyridine is used as a group to interact with methylation reagents such as halomethane or dimethyl sulfate. The nitrogen atom on the pyridine ring has a lone pair of electrons and has good nucleophilicity. The halogen atom or sulfonate group in the halomethane or dimethyl sulfate is a good leaving group. When the two meet, the nucleophilic substitution reaction occurs immediately, and the methyl group is then attached to a specific position on the pyridine ring to obtain the target product. However, this process requires attention to the selectivity of the reaction. Due to the different activities of different positions of the pyridine ring, suitable catalysts and reaction conditions are often required to promote the reaction towards the direction of generating 2% 2C4-dimethoxypyridine.
    Second, pyridine derivatives containing appropriate substituents can be started. If there are pyridine derivatives with groups that can be converted to methoxy groups at the 2nd or 4th positions, such as halogen atoms, hydroxyl groups, etc., they can be converted to methoxy groups by nucleophilic substitution reactions or other functional group conversion reactions. For example, 2-halopyridine is reacted with sodium methoxide in a suitable solvent, and the halogen atom is replaced by methoxy group, and then the methyl group is introduced by a similar methylation method at the 4th position, which can also achieve the purpose of synthesis.
    Third, it is synthesized by constructing a pyridine ring. Through a multi-step reaction, the pyridine ring structure is constructed with appropriate raw materials, and the introduction of methyl and methoxy groups is included in the design of the reaction route. For example, using β-ketone esters, ammonia and appropriate halogenated hydrocarbons as raw materials, through a series of reactions such as condensation and cyclization, the pyridine ring is gradually constructed, and methyl and methoxy groups are introduced in suitable steps. Although there are many steps in this way, the position and type of pyridine ring substituents can be more accurately controlled.
    All synthesis methods have advantages and disadvantages. In practical application, when considering the availability of raw materials, the difficulty of reaction, cost and yield, etc., the most suitable method is selected.
    What are the applications of 2,4-dimethoxypyridine?
    2% 2C4-dimethoxypyridine, which is widely used. In the field of medicine, it is an important pharmaceutical intermediate. In the synthesis of many drugs, it is often used as a starting material or key intermediate, and through a series of chemical reactions, drugs with specific therapeutic effects are obtained, such as certain antibiotics, cardiovascular drugs, etc., to help treat diseases.
    In the field of pesticides, it is also indispensable. It can be used to synthesize a variety of highly efficient and low-toxicity pesticides. With its special chemical structure, it enhances the control effect of pesticides on pests, guarantees the growth of crops, increases yields, and reduces the damage of pests and diseases to agricultural production.
    In the field of organic synthesis, it plays a key role. As an organic synthesis reagent, it can participate in many organic reactions, such as nucleophilic substitution reactions, oxidation reactions, etc., to help chemists construct complex organic molecular structures, providing strong support for the research and development of new materials and fine chemicals. In the field of materials science, some polymer materials involved in the synthesis of 2% 2C4-dimethoxypyridine have unique properties, such as good thermal stability and mechanical properties, and have potential application value in high-end fields such as aerospace and electronics.
    What is the approximate market price of 2,4-dimethoxypyridine?
    Today's question, what is the market price of 2,4-dimethoxypyridine? This is an important compound in the field of fine chemicals, and its price often varies depending on quality, purity, and supply and demand.
    Looking at the general situation of the market, the price per kilogram of ordinary purity may be between hundreds and thousands of yuan. If its purity is extremely high, such as used in high-precision fields such as pharmaceuticals, the price will rise, and the price will rise per kilogram or more than 10,000 yuan.
    Its price fluctuates, and the relationship between supply and demand is the key reason. When the market demand is strong and the supply is relatively scarce, the price will rise; conversely, if the supply exceeds the demand, the price will decline. And the production process and raw material cost also have a significant impact on its price. If raw materials are scarce, or the production process is complex, the cost will increase, and the price will increase accordingly.
    Therefore, in order to know the exact market price, it is necessary to carefully observe the market dynamics, consult multiple suppliers, and comprehensively consider factors such as quality and purity to obtain a more accurate price.