2 4 Dichloro 5 Aminopyridine
pyridine pyrrole pyrazine piperidine piperazine

2,4-dichloro-5-aminopyridine

    Specifications

    HS Code

    679253

    Chemical Formula C5H4Cl2N2
    Molecular Weight 163.005 g/mol
    Appearance White to off - white solid
    Melting Point 135 - 139 °C
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
    Odor Odorless or very faint odor
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
    Where to Buy 2,4-dichloro-5-aminopyridine in China?
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    Frequently Asked Questions

    As a leading 2,4-dichloro-5-aminopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,4-dichloro-5-aminopyridine?
    2% 2C4-difluoro-5-aminopyridine, which has a wide range of uses. In the field of pharmaceutical synthesis, it is often used as a key intermediate. Due to its specific chemical structure, it can react ingeniously with many reagents and undergo a series of delicate transformations to eventually become a drug with specific pharmacological activity. For example, when developing antibacterial drugs, by virtue of its structural characteristics, it participates in the construction of the core skeleton of the drug, giving the drug a unique inhibition or killing effect on specific bacteria, helping to fight the disease of stubborn bacteria.
    In the creation of pesticides, 2% 2C4-difluoro-5-aminopyridine is also indispensable. It can be integrated into the molecular structure of pesticides through chemical synthesis paths, giving pesticides excellent properties such as high-efficiency insecticides and weeding. After ingenious design, it can precisely act on the specific physiological links of target organisms, or interfere with the nervous system of pests, or hinder the photosynthesis of weeds, so as to achieve the purpose of agricultural pest control and weed control, and improve crop yield and quality.
    In addition, it has also emerged in the field of materials science. It can be used to prepare materials with special photoelectric properties. Due to the unique electronic effect of fluorine atoms and amino groups in the structure, it can optimize the electrical and optical properties of materials. In the research and development of organic Light Emitting Diode (OLED) materials, the appropriate introduction of this compound can effectively improve the luminous efficiency and stability of the material, and promote the development of display technology to better image quality and lower energy consumption. In short, 2% 2C4-difluoro-5-aminopyridine has key applications in many fields and has made great contributions to technological progress and innovation in various fields.
    What are the synthesis methods of 2,4-dichloro-5-aminopyridine?
    There are several methods for the synthesis of 2% 2C4-dihydro-5-hydroxypyrimidine. One method is also to use the corresponding aldehyde, urea and ethyl acetoacetate as raw materials, in the presence of appropriate catalysts, through condensation reaction. The reaction conditions are mild and easy to operate, but the yield may vary depending on the type and dosage of the catalyst.
    There are also those who use diethyl malonate, formamide and aldehyde as starting materials. First, diethyl malonate is condensed with formamide, and then reacted with aldehyde, and after multiple steps of conversion, the final product is obtained. Although this approach is slightly complicated, the purity and yield of the product can be improved by fine regulation of each step of the reaction.
    There are also people who use microwave radiation method. The reactants are exposed to microwave radiation to accelerate the reaction process, shorten the reaction time, and improve the selectivity of the reaction. This is an emerging synthesis method with high efficiency and energy saving characteristics, which has attracted the attention of this field.
    Complex biosynthesis method uses specific enzymes or microorganisms to catalyze the synthesis of 2% 2C4-dihydro-5-hydroxypyrimidine under mild conditions. This method is green and environmentally friendly, but it is not widely used in industrial production due to the stability and cost of biocatalysts.
    All synthetic methods have their own advantages and disadvantages. In practical applications, they should be carefully selected according to specific needs and conditions in order to achieve the best synthetic effect.
    What are the physical and chemical properties of 2,4-dichloro-5-aminopyridine?
    2% 2C4-difluoro-5-hydroxypyridine is an organic compound, and its physical and chemical properties are as follows:
    Viewed at room temperature, it is mostly white to light yellow solid or crystalline, and this state is derived from the intermolecular forces and arrangements. Because the hydroxyl group can cause the formation of hydrogen bonds between molecules, strengthen the intermolecular interaction, and cause the substance to be in a solid state.
    Smell it, or it has a weak special smell, but this smell is not pungent or strong, and its taste is derived from the molecular structure and functional group characteristics.
    In terms of melting point, the melting point is between 100-120 ° C, and the boiling point is about 250-270 ° C. The hydrogen bond formed by the hydroxyl group enhances the intermolecular force, and more energy is required to change its state, so the melting boiling point is higher.
    In terms of solubility, it is slightly soluble in water, but easily soluble in common organic solvents, such as ethanol, acetone, dichloromethane, etc. Because it contains hydroxyl groups, it has a certain polarity and can form hydrogen bonds with water, but the pyridine ring is a hydrophobic structure, resulting in limited solubility in water; the polarity of the organic solvent is adapted to the structure, which is conducive to molecular dispersion, so the solubility is good.
    In terms of chemical activity, the hydroxyl group is active and can participate in many reactions. When exposed to acids, the hydroxyl group is easily protonated, enhancing its nucleophilicity, and prone to substitution reactions, such as reacting with halogenated hydrocarbons to form ethers At the same time, the pyridine ring is aromatic and the electron cloud distribution is special, which makes the carbon atoms on the ring electrophilic and can react with nucleophiles. Under suitable conditions, nitrification, halogenation, alkylation and other reactions can occur. It is widely used in the field of organic synthesis and is often used as a key intermediate for the preparation of drugs, pesticides and functional materials.
    What is the price of 2,4-dichloro-5-aminopyridine in the market?
    2% 2C4-difluoro-5-hydroxypyridine, the price of this product is difficult to discuss in the market. The change in its price depends on multiple ends.
    The purity of its quality, the price must be higher than that of the miscellaneous. Pure quality needs to be prepared by exquisite methods, which are complex and expensive, and the price is high. And the quantity of its production is also related to the price. If the production is abundant, the supply exceeds the demand, and the price may decline; if the production is limited, the demand exceeds the supply, and the price will rise. And the demand of the market is also the main reason. If various industries need it, the price will also rise.
    Furthermore, the materials and methods of making this product are also related to the price. If the material is easy to obtain and the method is simple, the price may be inexpensive; if the material is thin and difficult, the price must be high. And the rules of trade and the cost of transportation can cause the price to change.
    In order to know the exact price, when you carefully observe the movement of the market, the quality of the situation, and the state of production and supply, you can get a near-real price.
    What are the storage conditions for 2,4-dichloro-5-aminopyridine?
    2% 2C4-dihydro-5-aminopyrimidine is a rare medicinal material, and its storage conditions are crucial, which is related to the efficacy and quality of the medicinal material. According to the principles of "Tiangong Kaiwu", such exquisite medicinal materials should be stored in a clean, dry and cool place.
    In a clean place, due to the nature of debris and filth, it is easy to disturb the medicinal material. If it is in a dirty place, the medicinal material is easily contaminated with foreign gas, causing its essential variation and the efficacy of the medicinal material to be damaged.
    The need for dryness is to fear moisture from the medicinal material. If moisture invades, the medicinal material is prone to mildew and rot. Once mildew, its medicinal power is lost, and even more poisonous, and the damage is endless. Therefore, in the place of preservation, it is necessary to avoid water and moisture, and it is advisable to use lime and other substances to absorb moisture to keep it dry.
    The need for shade, because the medicinal materials are afraid of heat. Under high temperature, the ingredients of the medicinal materials are easy to evaporate and decompose, and the efficacy of the medicinal materials is greatly reduced. Therefore, it is hidden in a cool place, such as a cellar or a deep pavilion, so that it is not fumigated by the hot sun or attacked by hot air, so that its medicinal power can be maintained for a long time.
    And the medicinal materials should be stored in a closed vessel to prevent them from being too much in contact with the outside air, causing oxidation of the ingredients and deterioration in quality. The vessels, either for porcelain pots or copper boxes, are all well sealed and can protect the medicinal materials inside. Therefore, 2% 2C4-dihydro-5-aminopyrimidine should be properly stored for medicinal use without losing its delicate function.