2 4 Diboromo 3 Iodopyridine
pyridine pyrrole pyrazine piperidine piperazine

2,4-Diboromo-3-iodopyridine

    Specifications

    HS Code

    931484

    Chemical Formula C5H2B2Br2IN
    Molecular Weight 384.60
    Appearance Solid (usually a powder)
    Physical State At Room Temperature Solid
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
    Melting Point Typically in the range of 110 - 115 °C
    Odor Odorless or very faint odor
    Stability Stable under normal conditions, but sensitive to moisture and strong acids/bases
    Hazard Class Irritant (may cause skin, eye and respiratory irritation)

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    General Information
    Where to Buy 2,4-Diboromo-3-iodopyridine in China?
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    Frequently Asked Questions

    As a leading 2,4-Diboromo-3-iodopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,4-dibromo-3-iodopyridine?
    2% 2C4-dibromo-3-nitropyridine is mainly used as a key intermediate in the field of organic synthesis. In the field of medicinal chemistry, it can use its special structure to construct compounds with specific pharmacological activities through a series of chemical reactions. For example, the development and preparation of some antibacterial and anti-tumor drugs will involve its participation. Through it, specific groups are introduced to shape the activity check point of drug molecules, improve the compatibility and affinity of drugs and targets, and then enhance the efficacy of drugs. In the field of materials science, it can be used as a starting material for the synthesis of functional materials, such as the preparation of organic materials with specific photoelectric properties, and the use of its structural properties to endow the materials with unique properties such as electron transmission, optical absorption or emission, in order to meet the needs of photoelectric devices and other fields for special material properties.
    "Tiangong Kaiwu" cloud: "This second product has a wide range of uses. In the way of medicine, it can be used as the basis for the processing of medicinal stones, in order to become an agent for treating diseases and diseases; in the manufacture of utensils, it can also be used as a starting material to cultivate novel and practical materials to meet various needs." It is the foundation for the construction of various compounds, enabling craftsmen to create a wide range of products according to their characteristics. It plays an indispensable role in the fields of medicine and materials.
    What are the physical properties of 2,4-dibromo-3-iodopyridine?
    2% 2C4-dibromo-3-iodobenzoic acid is an organic compound. Its physical properties are as follows:
    In appearance, it is often in the state of off-white to light yellow crystalline powder. This form is quite common in many organic synthesis reactions and is easy to handle and handle.
    Melting point is between about 132-136 ° C. Melting point is an important physical property of a substance. This temperature range indicates that the compound will undergo a phase transition from solid to liquid in this specific temperature range. With this property, its purity can be identified by melting point determination. If the purity is high, the melting point range is relatively narrow and close to the theoretical value; if it contains impurities, the melting point will be reduced and the range will be wider.
    In terms of solubility, it is slightly soluble in water, but soluble in some organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. This difference in solubility is due to its molecular structure, which contains groups such as benzene ring and halogen atom, which make it weakly interact with solvents with strong polarity such as water, so it is difficult to dissolve; while it can dissolve with some organic solvents through intermolecular forces. This solubility characteristic is of great significance in organic synthesis experiments. For example, when selecting a reaction solvent, its solubility needs to be considered so that the reaction can be carried out efficiently in a homogeneous system, and in the product separation and purification steps, appropriate methods, such as extraction, can also be selected according to the difference in solubility to obtain high-purity products.
    Is the chemical properties of 2,4-dibromo-3-iodopyridine stable?
    The chemical properties of 2% 2C4-dibromo-3-nitropyridine are relatively stable under normal conditions. In this compound, the presence of bromine atom and nitro group endows it with specific reactivity and chemical properties.
    Bromine atom has certain nucleophilic substitution activity, which can be replaced by other nucleophilic reagents under suitable reaction conditions, so as to realize the structural modification and transformation of the compound. However, the reaction requires specific temperature, solvent and catalyst conditions to occur smoothly.
    Nitro is also an important functional group, which has strong electron-withdrawing properties and can affect the electron cloud density of the pyridine ring, which in turn affects the reactivity and physical properties of the compound. Under certain conditions, nitro groups can be reduced to other functional groups such as amino groups, opening up further chemical synthesis paths.
    However, it needs to be understood that this compound is relatively stable in the conventional storage and operation environment without the excitation of external specific chemical reagents and conditions. However, the properties of chemical substances often vary depending on the environment. In case of extreme conditions such as high temperature, strong acid and base, strong oxidizing agents or reducing agents, its stability may be affected, triggering various chemical reactions such as decomposition, substitution, oxidation and reduction. Therefore, when considering the chemical stability of 2% 2C4-dibromo-3-nitropyridine, depending on the specific environmental conditions, it is relatively stable under generally mild conditions, but in specific chemical environments, it may exhibit abundant chemical reactivity.
    What are the synthesis methods of 2,4-dibromo-3-iodopyridine?
    To prepare 2,4-dichloro-3-cyanopyridine, there are many ways to synthesize it, which are described below.
    First, it can be started from pyridine compounds. Using suitable pyridine derivatives as raw materials, chlorine atoms are introduced at specific positions first. Suitable chlorination reagents, such as phosphorus oxychloride, can be selected. Under appropriate reaction conditions, such as controlling temperature, reaction time and proportion of reactants, chlorine atoms replace the corresponding hydrogen atoms on the pyridine ring to achieve chlorination at specific positions. Subsequently, cyanyl groups are introduced. This can be done with the help of cyanide reagents, such as potassium cyanide, etc., in the presence of suitable catalysts, nucleophilic substitution reaction occurs, and the cyanyl group is introduced into the target position to obtain 2,4-dichloro-3-cyanopyridine.
    Second, it can also be started from other nitrogen-containing heterocyclic compounds. After a multi-step reaction, the pyridine ring is gradually constructed and the desired substituent is introduced. First, the heterocyclic structure containing the appropriate substituent is constructed, and the pyridine ring skeleton is formed by cyclization reaction. Then the halogenation reaction is used to introduce chlorine atoms precisely at the 2nd and 4th positions, and then the cyanide group is introduced at the 3rd position by cyan In this process, the control of the conditions of each step of the reaction is very critical, and the choice of temperature, solvent and catalyst will all affect the yield and selectivity of the reaction.
    Third, aromatic amines can also be considered as starting materials. Through a series of classic organic reactions such as diazotization and Sandmeier reaction, it is gradually converted into chlorine-containing pyridine derivatives, and then cyanyl groups are introduced. First, the aromatic amine is reacted with diazotization to obtain diazoic salts, and then the Sandmeier reaction is used to convert diazoyl groups into chlorine atoms and introduce chlorine substituents. Afterwards, 2,4-dichloro-3-cyanopyridine was synthesized through the construction of pyridine ring and cyanylation reaction.
    All these synthesis methods have their own advantages and disadvantages, and they need to be selected according to actual conditions, such as the availability of raw materials, the difficulty of reaction, and production costs.
    What is the market price of 2,4-dibromo-3-iodopyridine?
    Today there is 2,4-dichloro-3-iodobenzoic acid. What is the price on the market? This is a commonly used chemical product, and its price varies depending on quality, quantity, and market conditions.
    If the quality is high and the quantity is huge, or due to the benefit of scale, the price is slightly cheaper. However, if the quality is high and the quantity is small, the price will be high. And the change of market supply and demand also affects its price. If there are many people who want it, the supply will be scarce, and the price will rise; otherwise, it will drop.
    Looking at the past market, the price of this product per kilogram may be between hundreds of gold and thousands of gold. However, the market of chemical industry is changing, and the current price is not sustainable. If you want to know the exact price, you should consult chemical companies, brokers, or look at various industry information and trading platforms to obtain a real-time price, so as to make an accurate judgment and make no difference in business.