2 4 4 Bromo Phenyl 1 Methyl 1h Imidazol 2 Yl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-[4-(4-Bromo-phenyl)-1-methyl-1H-imidazol-2-yl]-pyridine

    Specifications

    HS Code

    373249

    Chemical Formula C15H12BrN3
    Molecular Weight 314.18
    Appearance Solid (predicted)
    Solubility Soluble in organic solvents (predicted)

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    What are the main uses of 2- [4- (4-bromophenyl) -1-methyl-1H-imidazole-2-yl] pyridine?
    This is a question about the structure and use of organic chemicals. 2 - [4 - (4 - cyanobenzyl) -1 - methyl - 1H - pyrazole - 2 - yl] This substance is of great significance in the field of pharmaceutical synthesis.
    In the creation of new drugs, it may serve as a key intermediate. Due to the chemical activity of specific groups in its structure, it can be cleverly connected with other molecules through chemical reactions to construct complex compounds with specific pharmacological activities. For example, the pyrazole ring structure is common in many drug molecules, which can affect the interaction between drugs and targets, or enhance the affinity and selectivity of drugs to specific receptors, paving the way for the development of specific drugs for specific diseases, such as inflammation and tumors.
    In the field of pesticide synthesis, this substance also has potential applications. Its structural characteristics may endow pesticides with unique biological activities, or can enhance the inhibition and killing effects of pests and pathogens. At the same time, with its chemical stability, it can maintain a certain age in the natural environment, ensure the durability of pesticide effects, and have relatively little impact on the environment, and help the development of green pesticides.
    In addition, in the field of materials science, it may be able to participate in the preparation of functional materials. Due to its unique chemical structure, it may endow materials with unique properties such as optics and electricity, contributing to the development of new functional materials.
    What are the synthesis methods of 2- [4- (4-bromophenyl) -1-methyl-1H-imidazole-2-yl] pyridine
    To prepare this 2 - [4 - (4 - cyanobenzyl) - 1 - methyl - 1H - indole - 2 - yl] compound, there are many synthesis methods.
    First, the core indole structure can be constructed through a multi-step reaction from the starting material. First, the indole ring is formed by a condensation reaction with a suitable nitrogen and carbon source. For example, an aniline derivative with a suitable substituent can be combined with a specific carbonyl compound under acidic or basic catalytic conditions to undergo a condensation cyclization reaction to form an indole parent nucleus. In the process of constructing the indole ring, the reaction conditions are precisely controlled to ensure that the substitutions such as methyl and cyanobenzyl are introduced at suitable positions. This step requires strict control of the proportion of reactants, reaction temperature and time to improve the yield and purity of the target product.
    Second, the stepwise modification method is adopted. The basic indole derivatives are first prepared, and then the cyanobenzyl and methyl groups are introduced one by one through nucleophilic substitution and electrophilic substitution. For example, the 2-haloindole derivative is synthesized first, and then the cyanobenzyl negative ion or its equivalent reagent is used to introduce the cyanobenzyl group into the 2-position through nucleophilic substitution reaction; after that, the 1-position methylation is achieved under basic conditions by suitable methylation reagents, such as iodomethane. The key to this method is the separation and purification of the intermediate in each step of the reaction to ensure the smooth progress of the subsequent reaction.
    Third, the coupling reaction catalyzed by transition metals can be used. For example, using a palladium-catalyzed coupling reaction, a halogen or borate containing indole fragments is coupled with a cyanobenzyl halogen or an alkenyl halogen in the presence of suitable ligands and bases to achieve the synthesis of the target compound. This method has the advantages of mild reaction conditions and high selectivity, but suitable catalysts, ligands and reaction solvents need to be screened to optimize the reaction effect.
    There are various methods for synthesizing this compound. It is necessary to consider the availability of starting materials, the difficulty of reaction conditions, the yield and purity of the target product and many other factors, and carefully select the appropriate synthesis strategy.
    What are the physical properties of 2- [4- (4-bromophenyl) -1-methyl-1H-imidazole-2-yl] pyridine
    This is a question about a complex organic compound. The compound is expressed as 2- [4- (4-cyanobenzyl) -1-methyl-1H-pyrazole-2-yl]. Its physical properties are as follows:
    In appearance, this compound is often presented in solid form, specifically or crystalline, which is due to the ordered arrangement of its intermolecular interactions. Different crystallization conditions, such as temperature, solvent type, and volatilization rate, may affect its crystallization morphology, either needle-like crystals or bulk crystals.
    In terms of color, the compound may be colorless to white in its pure state. However, if it is mixed with impurities, the color may change, such as when it contains some metal ion impurities, it may appear slightly yellow, fine powder and other colors.
    In terms of solubility, the dissolution of the compound in organic solvents is quite critical. Generally speaking, it has a certain solubility in polar organic solvents such as ethanol and acetone. Ethanol can interact with the compound molecules due to its moderate polar and hydrogen bonding ability, thereby promoting its dissolution. In non-polar organic solvents such as n-hexane, the solubility is lower, because the interaction between the non-polar solvent and the polar part of the compound is weak.
    Melting point is also one of its important physical properties. The compound has a specific melting point range, which is determined by intermolecular forces such as van der Waals forces, hydrogen bonds, etc. By accurately measuring the melting point, it can not only be used to identify the purity of the compound, but also provide an important reference for its synthesis, separation and storage.
    In terms of density, although the specific density value varies depending on the precise measurement conditions, it is roughly within a certain range, which is closely related to the molecular structure. The type, number and spatial arrangement of atoms in the molecule all affect the density.
    What is the market outlook for 2- [4- (4-bromophenyl) -1-methyl-1H-imidazole-2-yl] pyridine?
    2-%5B4-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1-%E7%94%B2%E5%9F%BA-1H-%E5%92%AA%E5%94%91-2-%E5%9F%BA%5D involved in this product, its market prospects are very complex and cannot be concluded.
    Looking at its foundation, the survival of benzyl has a huge impact on the overall structure. If 4- (4-benzyl) is partially stable, and ethyl, methyl and other groups are properly coordinated, it may emerge in the market conditions. Its application in related industries, such as medicine and chemical synthesis, if it meets the current market demand changes, it is especially green and efficient, or it can be favored.
    However, the market is changing, and the competition is fierce. If its synthesis process is cumbersome, costly, and the structure is exquisite, it will be difficult to compete with competitors to win at a low price and high quality. And if the activity and stability of 1H-pyrazole-2-base and other parts do not match the mainstream demand of the market, it may be blocked from entering the market.
    Furthermore, market demand often changes with policies and technological innovation. If the new regulations are strict, the standards of its composition and purity are improved, and this product fails to adapt, the prospect is worrying. Or the emergence of new technologies will give birth to better alternatives, which will also face difficulties.
    To sum up, the market prospect of 2-%5B4-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1-%E7%94%B2%E5%9F%BA-1H-%E5%92%AA%E5%94%91-2-%E5%9F%BA%5D has both hidden opportunities and challenges, which depend on the dynamic balance and proper response of multiple factors.
    In which fields is 2- [4- (4-bromophenyl) -1-methyl-1H-imidazole-2-yl] pyridine used?
    Ah, this is about 2- [4- (4-hydroxybenzyl) -1-methyl-1H-indole-2-yl], and I would like to know in what field it is used. Although the "Tiangong Kaiwu" does not detail the specific chemical structure of this thing, it can be deduced from the relevant category according to the method of ancient people's understanding of things.
    The things in the world all belong to the category. This organic compound with complex structure may be involved in the field of medicine. The ancient healer, seek herbs and stones, and make prescriptions to treat diseases. Today's pharmaceutical research and development is also exploring the efficacy of various compounds. If this 2- [4- (4-hydroxybenzyl) -1-methyl-1H-indole-2-yl], or has unique pharmacological activity, it can be used as a pharmaceutical active ingredient to treat certain diseases.
    In addition, the chemical industry may also use it. There were ancient alchemy casters, but today the chemical industry is fine. This compound may be used as a chemical raw material, synthesized and converted to obtain special materials, dyes, etc. In the chemical industry, the improvement of material properties often depends on the clever use of various compounds, which may be a boost.
    Or it is useful in agriculture. Ancient farming, application of heavy fertilizer medicine. Today's agricultural science and technology also seeks new compounds to promote crop growth and prevent pests and diseases. This 2- [4- (4-hydroxybenzyl) -1-methyl-1H-indole-2-yl], or can be used as raw materials for new pesticides and plant growth regulators to help agricultural harvests.
    Although this is not detailed in "Tiangong Kaiwu", the principles of the world are the same in ancient and modern times. With the method of ancient observation and speculation, this compound may be used in the fields of medicine, chemical industry, agriculture, etc., and its use will be clarified in later generations.