2 4 4 4 5 5 Tetramethyl 1 3 2 Dioxaborolan 2 Yl Phenyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyridine

    Specifications

    HS Code

    796352

    Chemical Formula C18H24BNO2
    Molecular Weight 297.20
    Appearance Solid (usually white to off - white)
    Melting Point Typically in a certain range (data may vary)
    Solubility In Organic Solvents Soluble in many common organic solvents like dichloromethane, toluene
    Solubility In Water Insoluble
    Pka Value No relevant pKa for the whole molecule in common sense
    Stability Stable under normal conditions, but sensitive to strong oxidizing agents

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    Frequently Asked Questions

    As a leading 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2- (4- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) phenyl) pyridine?
    Looking at the compound you mentioned, its name is complicated, but I can analyze its chemical structure according to this. The name of this compound contains groups such as "4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentaborane-2-yl" and "phenyl".
    First look at "4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentaborane-2-yl", and it can be known that it is a cyclic structure. The ring contains boron and oxygen atoms, forming the skeleton of 1,3,2-dioxyboron heterocyclopentaborane. And two methyl groups are attached to each of the 4th and 5th positions of the ring, which is indicated by "4,4,5,5-tetramethyl" in the nomenclature.
    Then look at "phenyl", which is a common aromatic hydrocarbon group. It is connected by six carbon atoms with conjugated double bonds to form a hexagonal planar structure.
    This compound is formed by connecting a phenyl group to a specific position on "4,4,5,5-tetramethyl-1,3,2-dioxyboronheterocyclopentylborane-2-yl". The overall structure has both the characteristics of a cyclic boroxyl heterocycle and the aromatic properties of a phenyl group. Due to the presence of boron and oxygen atoms, the boroxyl heterocycle has specific electronic effects and reactivity, while the phenyl group endows the compound with certain stability and typical reaction characteristics of aromatic compounds. With this structure, the compound may have unique application and research value in the fields of organic synthesis and materials science.
    What are the main application fields of 2- (4- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) phenyl) pyridine?
    This question involves a 2 - (4 - (4, 4, 5, 5 - tetramethyl - 1, 3, 2 - dioxyboron heterocyclohexane - 2 - yl) phenyl) group, whose main application field is quite wide.
    In the field of organic synthesis, this group is like a delicate key that can open the door of many reactions. With its unique structure, it can participate in a variety of coupling reactions, such as Suzuki - Miyaura coupling reaction is one of them. In this reaction, this group acts as a boronylation reagent, joins hands with halogenated aromatics or olefins, and with the help of palladium catalysts, efficiently forms carbon-carbon bonds, paving the way for the synthesis of complex organic molecules. The synthesis of many biologically active natural products and pharmaceutical intermediates relies on this kind of reaction, which greatly expands the boundaries of organic synthesis chemistry.
    The field of materials science is also difficult to find. This group can be integrated into polymer materials to give materials unique electrical and optical properties. For example, the polymerization of monomers containing this group to prepare polymers may enable materials to have excellent photoelectric conversion properties, making them stand out in optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells, and contributing to the development of high-performance new materials.
    In the field of pharmaceutical chemistry, this group can play an important role. By introducing this group to modify drug molecules, the physicochemical properties of drugs can be improved, such as improving the solubility and stability of drugs, and optimizing pharmacokinetic properties. After some anti-cancer drugs are modified, they are more easily absorbed by cancer cells, enhancing the efficacy of drugs, and reducing the toxic and side effects on normal cells, which brings new opportunities for the development of new drugs.
    What are the synthesis methods of 2- (4- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) phenyl) pyridine?
    To prepare 2- (4- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentane-2-yl) phenyl) boronic acid, there are many synthesis methods, which are described in detail below.
    First, it can be achieved by the reaction of halogenated aromatic hydrocarbons with boron reagents. Halogenated 2- (4-halogenated phenyl) benzene is used as the starting material. Under the catalytic action of palladium catalyst such as tetra- (triphenylphosphine) palladium, it reacts with diphenylpyronacol borate to generate the corresponding borate ester intermediate. Then, the intermediate is hydrolyzed under basic conditions to obtain the target product. In this process, the halogen atom activity of halogenated aromatic hydrocarbons is very critical, with the highest activity of iodine, followed by bromide, and relatively low activity of chlorine. The choice of suitable activity can improve the reaction efficiency. At the same time, the amount of palladium catalyst, reaction temperature and time need to be carefully controlled to ensure sufficient reaction and minimal side reactions.
    Second, the Grignard reagent method is also a commonly used method. First, halogenated 2- (4-halogenated phenyl) benzene is made into Grignard reagent, and then reacts with borate esters such as trimethyl borate. The resulting product is acidic hydrolyzed, and the target product can also be obtained. When preparing Grignard reagent, the reaction system needs to be strictly anhydrous and oxygen-free, and the quality and dosage of magnesium chips will also affect the reaction. In the subsequent reaction with borate esters, the control of temperature and reaction time determines the yield and purity of the product.
    Furthermore, it can also be synthesized by Suzuki reaction. Halogenated 2- (4-halogenated phenyl) benzene and 2-borate phenylboronic acid pinacol ester are coupled under basic conditions and the action of palladium catalyst, and the target product can be directly formed. In this reaction, the type and dosage of bases, the activity of catalysts, and the choice of reaction solvents all have a great impact on the reaction process. Inorganic bases such as potassium carbonate and sodium carbonate are often used to provide an alkaline environment, and different solvents have different solubility to reactants and catalysts, which in turn affects the reaction rate and selectivity.
    The above methods have their own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider many factors such as the availability of raw materials, cost, and difficulty in controlling reaction conditions, and carefully select the best method to achieve efficient, economical and environmentally friendly synthesis goals.
    What are the physicochemical properties of 2- (4- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) phenyl) pyridine?
    Looking at what you said, the things described seem to be extremely complicated. However, according to the clues in this, it seems to be a rather strange compound.
    This substance is composed of a variety of groups, including 4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane and 2-groups. The combination of these structures makes its physical and chemical properties unique.
    In terms of physical properties, or due to the spatial arrangement and interaction of groups in the structure, its morphology may take on a specific state. The crystallization habit and density of tetramethyl groups are affected by the steric hindrance effect or the three-dimensional configuration of this substance. The structure of dioxboron heterocyclopentane may be different in solubility due to the characteristics of boron-oxygen bonds, or show better solubility in specific organic solvents.
    As for chemical properties, boron atoms in the structure of dioxboron heterocyclopentane are electron-deficient and easily react with electron-rich bodies, which can be used as Lewis acid to participate in many organic reactions. If the 2-group part is an active group, it may further participate in nucleophilic and electrophilic reactions, making this substance have potential uses in the field of organic synthesis. The uniqueness of its structure, or the specific properties of this substance in catalysis, material preparation, etc., can be used as a key structural unit for the construction of new functional materials. Overall, due to the unique combination of groups, the physical and chemical properties of this substance hold many mysteries worth exploring.
    What is the market price of 2- (4- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) phenyl) pyridine?
    I think what you are talking about seems to be a rather complex organic compound. However, it is not easy to know the price situation in the market. The price of such compounds is often determined by many factors.
    First, the cost of raw materials. If the raw material for the synthesis of this 2- (4- (4,4,5,5-tetramethyl-1,3,2-dioxoboronheterocyclopentane-2-yl) phenyl) is difficult to obtain, or its own value is high, the price of this compound must not be low.
    Second, the difficulty of synthesis. Looking at its structure, it may require delicate synthesis steps and specific reaction conditions. Special catalysts, strict temperature and pressure control, etc. are required during the synthesis process, which will increase the cost and affect its market price.
    Third, market demand. If this compound has extensive and urgent demand in the fields of medicine, materials science, etc., and the supply exceeds the demand, its price will rise; on the contrary, if there is little demand, the price will not be high.
    Fourth, production scale. Large-scale production may reduce unit costs due to scale effects, but small-scale production is relatively expensive and the price will be different.
    And the price of this compound may also fluctuate greatly due to differences in purity and Quality Standards. Therefore, it is difficult to say exactly what its price is in the market. Only by detailed investigation of chemical product market information, consulting professional chemical traders or experts in related fields can more accurate price information be obtained.