2,3-pyridinediamine, 5-(trifluoromethyl)-

2% 2C3-pyridinediamine, 5- (trifluoromethyl) is useful in the fields of medicine, pesticides and materials.
In the field of medicine, it is a key intermediate for the synthesis of new anti-cancer, antibacterial and antiviral drugs. Because the structure of pyridine is closely related to biological activity, the introduction of trifluoromethyl can change the physical and chemical properties of the compound, such as lipophilicity and stability, so that the drug can more easily penetrate the biofilm and enhance the interaction with the target. For example, based on it, anti-cancer drugs that can precisely act on specific proteins of cancer cells can be prepared, block the proliferation signaling pathway of cancer cells, and inhibit the growth of cancer cells. < Br >
In the field of pesticides, it can be used to create high-efficiency, low-toxicity, and environmentally friendly insecticides, fungicides and herbicides. The structure of pyridine diamine and trifluoromethyl gives pesticides unique biological activity and selectivity, which can specifically inhibit specific enzymes or physiological processes in harmful organisms. If the prepared insecticide can act on the insect nervous system, interfere with its nerve conduction, achieve insecticidal effect, and has low toxicity to non-target organisms, reducing damage to the ecological environment.
In the field of materials, this compound can be used to prepare functional polymer materials, optical materials, etc. In functional polymer materials, it can impart special electrical, optical or thermal properties to the materials. In terms of optical materials, it can be used as a key component of luminescent materials. With its unique molecular structure and electronic properties, it can achieve high-efficiency luminescence and be used in organic Light Emitting Diodes (OLEDs) and other fields to improve the performance of display technology.

2% 2C3 - pyridinediamine% 2C5- (trifluoromethyl) - that is, 5- (trifluoromethyl) -2,3 - pyridinediamine. The physical properties of this substance, let me tell you one by one.
Its appearance is often solid, and as for the color, it is mostly white to off-white, which is a common shape. Looking at its texture, it is delicate and uniform.
When it comes to the melting point, it can be obtained through many experiments, which is about a specific temperature range. This melting point characteristic is of great significance when identifying and purifying this substance. The exact value of its melting point is one of the important physical signs of this substance, like a human fingerprint, which is unique. < Br >
In terms of solubility, in specific organic solvents, such as a certain type of polar solvent, it can show a certain solubility. This solubility property is crucial in chemical synthesis and related process operations. If it needs to be mixed with other substances to understand its solubility, it is possible to know which solvent to choose to make the reaction smoother.
Density is also a key item in its physical properties. After precise measurement and calculation, its density value can be known. This value is of great significance for accurately controlling the amount of materials used in chemical production. Knowing its density allows you to know the mass of the substance at a certain volume, and then rationally plan the reaction ratio.
In addition, its stability is also a consideration of physical properties. Under normal environmental conditions, 5- (trifluoromethyl) -2,3 -pyridinediamine can maintain a relatively stable state. However, in case of extreme temperature, humidity or special chemical atmosphere, its structure and properties may change.
In summary, the physical properties of 5- (trifluoromethyl) -2,3 -pyridinediamine, such as appearance, melting point, solubility, density and stability, are of indispensable importance in many fields such as chemical research and chemical production.

2% 2C3 -pyridylamine, 5- (trifluoromethyl) - This substance has unique chemical properties, let me tell you one by one.
It is basic, because the molecule contains amino groups, and the nitrogen atom in the amino group has lone pair electrons, which can bind protons. In acidic media, it can form salts. If it interacts with hydrochloric acid, it produces corresponding ammonium salts. This is an important reaction property in an acid environment.
From the structural point of view, trifluoromethyl strongly absorbs electrons, causing the electron cloud density of the pyridine ring to change, which affects the activity and check point of electrophilic substitution reaction. The pyridine ring is aromatic, but the presence of trifluoromethyl makes the electron cloud on the ring biased towards the group, so the electrophilic substitution reaction is more difficult than that of pyridine, and the substitution check point is mostly in the area of relatively high electron cloud density, such as the 3-position of the pyridine ring (non-trifluoromethyl linked).
Its solubility, because the amino group can form hydrogen bonds, has a certain solubility in water and alcohol polar solvents, but the hydrophobicity of trifluoromethyl limits its high solubility in water, generally better in polar organic solvents. < Br >
In terms of thermal stability, the carbon-fluorine bond energy in the structure is high, the trifluoromethyl is stable, and the pyridine ring and the amino group are also relatively stable, so that this compound has a certain thermal stability. At the appropriate temperature, the structure is not easy to decompose.
In the redox reaction, the amino group can be oxidized. For example, under the action of strong oxidants, the amino group may be converted to nitro, nitroso, etc. The pyridine ring can also participate in the redox process under specific conditions.
This compound is rich in chemical properties and is influenced by the interaction of various groups in the structure. It has potential application value in organic synthesis, pharmaceutical chemistry and other fields. It will be further explored and utilized by future generations.

The synthesis method of 5- (trifluoromethyl) -2,3-pyridine diamine is not directly described in the ancient book "Tiangong Kaiwu", but one or two can be deduced from the ancient chemical process idea and the method of preparing similar compounds.
In the past, the preparation of organic compounds often began with natural materials. In the synthesis of 5- (trifluoromethyl) -2,3-pyridine diamine, natural substances containing pyridine structures can be found as starting materials. For example, in some plant or microbial metabolites, or the structural units of pyridine can be extracted and separated to obtain relatively pure pyridine-containing substrates.
The method of extraction has been used in ancient times. With an appropriate solvent, such as alcohols and ethers, leach the material containing the target substance, and use the difference in solubility to dissolve the pyridine substrate. During separation, or by distillation, the boiling point difference of different substances is used to obtain relatively pure pyridine raw materials.
After obtaining the pyridine raw material, if you want to introduce trifluoromethyl, although there is no advanced fluorination technology in ancient times, you can try to use fluorinated natural minerals, such as fluorite (CaF ²), after special treatment, to convert it into an active fluorine-containing reagent. The pyridine-containing substrate and the treated fluorine-containing reagent are tried to introduce trifluoromethyl under an appropriate reaction environment, such as a specific temperature and pressure. Temperature control or by means of charcoal fire, water bath, etc., pressure or in a sealed container, by heating or cooling to cause internal and external pressure difference to control.
After the introduction of trifluoromethyl, to form a diamine structure, or aminolysis reaction can be used. React with pyridine derivatives containing trifluoromethyl in an aqueous solution of ammonia or liquid ammonia. Although there is no precise reaction monitoring method in ancient times, the reaction process can be roughly judged according to the reaction phenomenon, such as color change, precipitation formation or not.
After the reaction is completed, the purification of the product is also the key. Or use the method of recrystallization, select an appropriate solvent, dissolve the product, slowly cool down, allow it to crystallize and precipitate, remove impurities, and obtain a relatively pure 5- (trifluoromethyl) -2,3-pyridinediamine.

I have not obtained the exact price of 2,3-pyridinediamine, 5- (trifluoromethyl) in the market. However, the price of such chemicals often varies according to a variety of reasons.
One is quality and quantity. For high purity, the price must be higher than ordinary ones; if you buy it in large quantities, there may be discounts, and the unit price may be reduced.
The second is source and supply. If it is produced in a common place with high production capacity, the price will be flat if the supply is sufficient; if the source is thin, the supply is less and the demand is more, and the price will increase.
The third is related to production and research. The preparation process is complicated and the research and development cost is high, and the price is also high.
The fourth depends on the place and method of transaction. Prices vary in different regions, and online and offline transaction costs also vary, so the price can be different.
Although there is no price range, if you want to know more, you can visit the website where chemical reagents are sold, consult chemical product suppliers, or communicate with industry insiders to get a close price.