2,3-pyridinediamine, 5-fluoro-

5-Fluorine-2,3-pyridinediamine is a kind of organic compound. It has specific chemical properties. The appearance of this substance is often solid, or in the state of crystalline powder. Due to the orderly arrangement of atoms in the molecular structure, it has a certain crystal form.
In terms of physical properties, its melting point and boiling point depend on the intermolecular force. Molecules contain fluorine atoms, amino groups and pyridine rings. Fluorine atoms have high electronegativity and special bonding with surrounding atoms, which has an impact on the melting point and boiling point. Generally speaking, the melting point of compounds containing such structures may be within a certain range, but the exact value needs to be determined experimentally and accurately.
Its solubility is also an important property. Because it contains polar amino groups, it may have a certain solubility in polar solvents such as water, and can interact with water molecules by means of hydrogen bonds. However, the pyridine ring and the fluorine atom have certain non-polarity, and may also have different dissolution behaviors in non-polar solvents. This needs to be carefully considered in chemical synthesis, separation and purification.
In terms of chemical properties, amino groups are active and reactive. They can participate in a variety of reactions, such as reacting with acids to form salts. Because amino nitrogen atoms have lone pairs of electrons, they are easy to bind protons. In organic synthesis, they can be used as nucleophiles to undergo nucleophilic substitution reactions with halogenated hydrocarbons, acyl halides, etc., thereby introducing different functional groups and expanding the molecular structure complexity.
Although fluorine atoms are small, their high electronegativity significantly affects the distribution of molecular electron clouds. It can change the electron cloud density of ortho-and para-carbon atoms, cause changes in the reactivity of pyridine rings, and affect the selectivity of the reaction check point in the electrophilic substitution reaction. The introduction of fluorine atoms often enhances the stability and biological activity of compounds, and is widely used in the field of medicinal chemistry.
5-fluoro-2,3-pyridinediamine has potential application value in materials science, drug development and other fields due to its special structure. Its chemical properties are active and provide various possibilities for organic synthesis.

5-Fluoro-2,3-pyridylamine has a wide range of uses. In the field of medicine, it is often a key raw material for the creation of new drugs. It has a unique chemical structure, or it can be modified and modified to produce compounds with specific pharmacological activities, such as anti-tumor drugs. Due to the unique growth and metabolism of tumor cells, this compound may be able to precisely act on tumor-related targets, hinder tumor cell proliferation and induce apoptosis, and pave a new way for the development of anti-cancer drugs.
In materials science, it also has important uses. It can be used as a basic unit for the construction of organic functional materials. Because it contains nitrogen heterocycles and fluorine atoms, it gives materials unique electrical, optical and thermal properties. Or it can be used to prepare organic Light Emitting Diode (OLED) materials, which can improve its luminous efficiency and better color purity, and help the development of display technology.
In the field of pesticides, it is also used. It can be reasonably designed and synthesized to obtain pesticides with high-efficiency insecticidal and bactericidal activities. It has high selectivity to specific pests or pathogens, can effectively eliminate pests, and has little impact on the environment and non-target organisms, which is in line with the development needs of modern green pesticides. In short, 5-fluoro-2,3-pyridylamine has important value and application potential in many fields such as medicine, materials, and pesticides.

The synthesis of 5-fluoro-2,3-pyridine diamine is an important matter in chemical preparation. The method often follows several paths.
First, it can be started from a suitable pyridine derivative. Choose a pyridine compound containing a suitable substituent, and replace the atom at a specific position with a fluorine atom by a halogenation reaction, then obtain a fluorine-containing pyridine intermediate. This halogenation process requires careful selection of halogenating reagents and reaction conditions. For example, by means of nucleophilic substitution, a suitable nucleophilic reagent interacts with halogenated pyridine, and an amino group is introduced to construct an amino group at the 2nd and 3rd positions of pyridine, and finally 5-fluoro-2,3-pyridine diamine is obtained. In a reaction, the properties of the solvent, the control of temperature, and the degree of reaction time are all related to the yield and purity of the product.
Second, it can also be formed by cyclization. Select a chain compound with a suitable functional group and cyclize it to form a pyridine ring. In this process, fluorine atoms and amino groups are introduced at the same time. For example, specific chain molecules containing nitrogen, fluorine, and cyclizable functional groups are cyclized and condensed under suitable catalysts and conditions to form a pyridine structure, and 2,3-diamino and 5-fluorine are generated at the expected position. This approach is the key to the choice of catalyst and the creation of the reaction environment. < Br >
Furthermore, the series reaction of multiple steps can also be carried out. First, the intermediate containing part of the target structure is prepared, and then various reactions are carried out in sequence, and fluorine atoms and amino groups are gradually added. This requires fine planning of the reaction sequence to avoid unnecessary side reactions, so as to achieve the purpose of efficient synthesis of 5-fluoro-2,3-pyridinediamine.

I look at your question, but I am inquiring about the market price range of 5-fluoro-2,3-pyridinediamine. However, the price of this chemical substance often changes due to multiple reasons, and it is difficult to be sure.
First, the difference in purity significantly affects its price. If the purity is extremely high and almost flawless, the price will be high; if it contains impurities and the purity is slightly inferior, the price may drop. Second, the purchase quantity is also a major factor. If you buy in bulk, merchants may offer discounts due to large quantities and large profits, and the unit price will decrease; if you only buy a small amount and use it for experimental trials, the price may be high. Third, the market supply and demand trend, the price is huge. If there are many people who want this item, the supply is small, and the price will rise; conversely, if the supply exceeds the demand, the price may drop.
As far as I know, the price fluctuates quite a lot in the market. In common cases, small purchases range from tens of yuan to hundreds of yuan per gram; if large purchases are made, kilograms or thousands of yuan per kilogram. However, this is only an approximate number, and the actual price may vary from time to time, from market to market, or fluctuate up and down. To know the exact price, when consulting chemical reagent suppliers and exploring the market in detail, you can get an accurate price.

5-Fluoro-2,3-pyridinediamine, the manufacturer of this substance, is involved in many pharmaceutical companies in this world. However, if you want to test its expertise in detail, you need to explore chemical classics and pharmaceutical company directories.
In the past, although there was no current fine chemical industry, the technology of pharmaceutical processing has already flourished. Today's 5-fluoro-2,3-pyridinediamine is used in pharmaceutical synthesis and is related to the development of drugs for the treatment of diseases. Its importance is obvious.
In the current pharmaceutical companies, or those who have prepared this substance by innovative synthesis methods, or those who have reduced its cost by large-scale production lines. Although it is difficult to list them all in detail, well-known pharmaceutical companies often focus on quality and technology, and strive to improve. The best among them may invest heavily in research and development to optimize the preparation process to achieve high-purity products; or fine control of the production process to ensure the stability of batches.
There are chemical research institutions, which cooperate with pharmaceutical companies to jointly research the best preparation method of this product. Therefore, if you want to find a manufacturer of 5-fluoro-2,3-pyridinediamine, you can only get the details when you visit the information of the chemical and pharmaceutical industries and carefully observe its process, production capacity and reputation.