2 3 Difuoro 5 Chloropyridine
pyridine pyrrole pyrazine piperidine piperazine

2,3-Difuoro-5-chloropyridine

    Specifications

    HS Code

    263604

    Chemical Formula C5H2ClF2N
    Molecular Weight 149.526
    Appearance Colorless to light yellow liquid
    Boiling Point 163 - 165 °C
    Melting Point N/A
    Density 1.39 g/cm³
    Solubility In Water Insoluble
    Flash Point 56.4 °C
    Vapor Pressure N/A
    Refractive Index 1.484

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    General Information
    Where to Buy 2,3-Difuoro-5-chloropyridine in China?
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    Frequently Asked Questions

    As a leading 2,3-Difuoro-5-chloropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3-difluoro-5-chloropyridine?
    2% 2C3-diene-5-propargyl has a key application in the field of chemical synthesis. Its main application is to participate in the construction of complex organic compounds. With its own unique unsaturated bond structure, it can use a variety of chemical reactions to expand and modify molecular structures.
    In the construction of cyclic compounds, this substance can be cyclic reacted to form cyclic molecules with specific structures and properties. Taking the Diels-Alder reaction as an example, 2% 2C3-diene-5-propargyl reacts with the diene body to form cyclic products with multiple structures, which are of great significance in the fields of medicinal chemistry and materials science. For example, in the development of new drugs, such cyclic structures may endow drugs with unique biological activities and pharmacological properties.
    At the same time, in the field of material synthesis, 2% 2C3-diene-5-propargyl can act as a functional monomer, and polymer materials containing unsaturated bonds can be prepared by polymerization. These polymer materials exhibit unique optical, electrical or mechanical properties due to the existence of unsaturated bonds, and can be applied to frontier fields such as optoelectronic devices and high-performance composites.
    In addition, it also has applications in the field of organometallic chemistry. It can coordinate with metals to form metal-organic complexes, which are excellent in catalytic reactions and can catalyze a variety of organic reactions, improve reaction efficiency and selectivity, and promote the further development of organic synthesis chemistry.
    What are the synthesis methods of 2,3-difluoro-5-chloropyridine?
    The synthesis method of 2% 2C3-diene-5-alkynyl compound can be done in the following ways.
    First, it is formed by the reaction of alkynes and conjugated diolefins. Select appropriate alkynes and conjugated diolefins, and under suitable catalyst and reaction conditions, the addition reaction of the two can occur. For example, with transition metal catalysts, complexes such as palladium and nickel, under mild temperature and pressure conditions, the triple bond of alkynes can be added to the double bond of conjugated diolefins, thereby constructing a 2% 2C3-diene-5-alkynyl structure. This reaction requires fine regulation of factors such as catalyst dosage, reaction temperature and time to prevent side reactions, such as over-addition or polymerization.
    Second, it is prepared by the reaction of halogenated olefins with alkynes. First, the halogenated conjugated diolefin derivatives containing halides are prepared, and then they are reacted with alkynes, such as alkynyl lithium and alkynyl magnesium halide, in an anhydrous and oxygen-free environment. Such nucleophilic substitution reactions can effectively introduce alkynes to form the target 2% 2C3-diene-5-alkynyl compound. When reacting, it is necessary to pay attention to the choice of solvent, usually anhydrous ether, tetrahydrofuran and other ether solvents, and strictly control the moisture and oxygen of the reaction system, so as not to affect the reaction process and the purity of the product.
    Third, use the multi-step reaction strategy in organic synthesis. Using simple starting materials, such as olefins, alkynes, halogenated hydrocarbons, etc., through a series of functional group conversion and carbon-carbon bond formation reactions, the target structure is gradually constructed. For example, halogenated olefins are obtained by halogenation of olefins, and then the conjugated diolefin structure is formed by elimination reaction, and then the alkynyl group is introduced by reaction with the alkynylation reagent. Although there are many steps in this approach, the reaction route can be flexibly designed according to the needs, and it is particularly suitable for the synthesis of complex 2% 2C3-diene-5-alkynyl compounds. During the synthesis process, the products of each reaction step need to be separated and purified to ensure the smooth progress of the next reaction and the quality of the final product.
    What is the market price of 2,3-difluoro-5-chloropyridine?
    I look at your question, but I am inquiring about the market price of 2,3-diethyl-5-cyanopyridine. However, the price of this product is often different due to changes in time, place, quality and supply and demand, and it is difficult to have a certain number.
    Between market changes, the price of the price is determined by many parties. The skills and quantity of the producer, and the needs of the user are all the main factors. And the market is impermanent. Every time the market fluctuates, the price of raw materials may rise or fall, or change due to political adjustments and regulations, so that the price is unstable.
    If you want to know the exact price, you can get a more accurate number by doing business, asking people, or participating in industry reports and price lists. The situation in the market is complicated, and you can only get the actual price to meet the needs of all things. Therefore, it is difficult to give you a definite number at this time. I hope you will follow this path and get the price information you want.
    What are the physical and chemical properties of 2,3-difluoro-5-chloropyridine?
    2% 2C3 -diethyl-5 -nitropyridine is an organic compound with unique physical and chemical properties. Although it did not have this name in the era of "Tiangong Kaiwu", its properties can be described as follows in ancient Chinese:
    This substance is either solid at room temperature. Looking at its appearance, it may be crystalline, and its color may be light yellow to light yellow, with a certain luster. Because it contains nitro groups, it is sensitive to light. Under light or gradual change of color, it is suitable to hide in the shade.
    When it comes to melting point, it has a specific value. When heated to a certain temperature, it begins to melt into a liquid state. This temperature is stable and can be used as one of the identification marks. Its boiling point is also characteristic, heated to the corresponding temperature, from liquid to gaseous state, and the gasification process needs to absorb specific heat.
    In terms of solubility, the solubility in water is low, because its molecular structure contains hydrophobic groups, and the affinity with water is weak. However, in some organic solvents, such as ethanol and ether, the solubility is high, and it can dissolve with organic solvents to form a uniform solution. This property makes it useful in organic synthesis and separation and purification.
    In terms of chemical properties, because it contains nitro groups, it is oxidizing, and when it encounters reducing agents, nitro groups may be reduced, causing molecular structure changes to form new compounds. And the pyridine ring is alkaline and can react with acids to form salts. Such reactions may change its physical properties, such as solubility and melting point. At the same time, the diethyl group makes the compound have a certain lipophilicity, and it is easy to pass through the cell membrane in vivo, and may have potential applications in the field of medicinal chemistry.
    What are the precautions for storing and transporting 2,3-difluoro-5-chloropyridine?
    2% 2C3-diethyl-5-nitropyridine needs to pay attention to many key matters during storage and transportation.
    When storing, the first priority is to choose the environment. It should be placed in a cool, dry and well-ventilated place, because the substance is sensitive to temperature and humidity. If the environment is humid, it is easy to cause moisture and deterioration, which affects the quality and performance; if the temperature is too high, or cause chemical reactions, it is very dangerous to be safe. And it needs to be kept away from fire and heat sources, because it has certain flammability, in case of open flame, hot topic or flammable explosion.
    Furthermore, storage needs to be classified and stored. Do not mix with oxidants, acids, alkalis, etc., because of their active chemical properties, contact with these substances, or react violently, resulting in danger. Be sure to store it separately and make a good mark for easy management and access.
    During transportation, the packaging must be tight. Select appropriate packaging materials to ensure that no damage and leakage are caused during transportation bumps. Transportation vehicles should also take protective measures and be equipped with corresponding fire equipment and leakage emergency treatment equipment, just in case.
    Transportation personnel must undergo professional training and be familiar with the characteristics of the substance and emergency treatment methods. During driving, abide by traffic rules and avoid violent actions such as sudden braking and sharp turns to prevent damage to the packaging. And the transportation route planning should be reasonable, avoid densely populated areas and important facilities, and reduce the risk of accidents. Only in this way can the safety of 2% 2C3-diethyl-5-nitropyridine be ensured during storage and transportation.