2 3 Dichloropyridine 4 Boronic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,3-Dichloropyridine-4-boronic acid

    Specifications

    HS Code

    230017

    Chemical Formula C5H4BCl2NO2
    Molecular Weight 190.804 g/mol
    Appearance White to off - white solid
    Cas Number 1072946-76-2
    Purity Typically high purity, e.g., 95%+
    Solubility Soluble in some organic solvents like DMSO, DMF
    Melting Point 152 - 157 °C
    Storage Condition Store in a cool, dry place, protected from moisture

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    General Information
    Where to Buy 2,3-Dichloropyridine-4-boronic acid in China?
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    Frequently Asked Questions

    As a leading 2,3-Dichloropyridine-4-boronic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3-dichloropyridine-4-boronic acid?
    2% 2C3-dihydroxyacetone-4-sulfonic acid, an important organic compound with a wide range of main uses.
    In the food industry, it can be used as a food additive. Due to its unique chemical properties, it can improve the color, taste and texture of food. For example, in baked goods, it can promote the formation of an attractive golden color on the skin of bread, and can extend the shelf life of food, allowing food to be stored for a longer time without changing quality.
    In the field of cosmetics, 2% 2C3-dihydroxyacetone-4-sulfonic acid also plays a key role. It is often used in tanning products, and can react with the amino acids on the surface of the skin to generate a color similar to the skin tone after sun exposure, achieving a natural tanning effect. Moreover, this process has relatively little stimulation to the skin, and is favored by many people who pursue tanning.
    Furthermore, in the pharmaceutical and chemical industry, it is also an important intermediate. With its own chemical structure, it can participate in many drug synthesis reactions and help prepare drugs with specific pharmacological activities, which is indispensable for pharmaceutical research and development.
    In conclusion, 2% 2C3-dihydroxyacetone-4-sulfonic acid has shown important uses in many fields such as food, cosmetics, medicine and chemical industry. With the continuous development of various industries, its application prospects will also be broader.
    What are the synthesis methods of 2,3-dichloropyridine-4-boronic acid?
    2% 2C3-difluoroethoxy-4-pyridinecarboxylic acid is an important intermediate in organic synthesis. The synthesis method is as follows:
    ** Method 1: Take an appropriate amount of pyridine as the starting material **
    , take an appropriate amount of pyridine in a suitable reaction vessel, at a specific temperature and under the action of a catalyst, carry out nucleophilic substitution reaction with fluorohalogenated alkanes, and introduce fluorine atoms. This process requires precise control of the reaction conditions, because the activity of pyridine ring and fluoroalkane reaction has a great influence on the yield of the product. After the reaction is completed, the fluoro-containing pyridine derivatives are obtained through separation and purification. Then, in another reaction system, under the action of a basic environment and a specific reagent, the side chain of the pyridine ring is carboxylated. This step requires selecting an appropriate base and reaction temperature to avoid overreaction of the pyridine ring. After the reaction is completed, 2% 2C3-difluoroethoxy-4-pyridinecarboxylic acid is obtained through acidification, recrystallization and other operations.
    ** Method 2:4-pyridinecarboxylic acid is used as the starting material **
    4-pyridinecarboxylic acid is placed in a reactor, and under specific solvent and alkaline conditions, it is reacted with halogenated difluoroethane to achieve the introduction of ethoxy groups. During the reaction, the polarity of the solvent, the strength of the base and the dosage will all affect the reaction process and the purity of the product. At the end of the reaction, the product is purified by extraction, column chromatography and other means. The starting materials of this method are relatively easy to obtain, the reaction steps are relatively simple, but the control of reaction conditions is also high, so as to improve the yield and purity of the product.
    ** Method 3: Through palladium catalytic coupling reaction **
    With suitable halogenated pyridine derivatives and fluoroenol ethers as raw materials, palladium catalytic coupling reaction occurs in a suitable solvent in the presence of palladium catalyst, ligand and base. Factors such as palladium catalyst activity, ligand structure, reaction temperature and time are crucial to the reaction. After the reaction is completed, the target product 2% 2C3-difluoroethoxy-4-pyridinecarboxylic acid is obtained through complex post-processing procedures such as vacuum distillation, silica gel column chromatography, etc. This method can effectively construct carbon-carbon and carbon-heteroatomic bonds, providing a new idea for product synthesis, but the cost of catalysts and ligands is high, which has certain limitations on industrial production.
    What are the physical properties of 2,3-dichloropyridine-4-boronic acid?
    2% 2C3-dihydropyridine-4-carboxylic acid is a class of organic compounds with the following physical properties:
    It is mostly crystalline solid at room temperature and has high stability. In terms of appearance, it is usually white to light yellow crystalline powder with pure and uniform color, which is convenient for precise application in various reactions and products.
    In terms of melting point, the melting point range of this substance is clear, usually in a specific range, like the melting point of some dihydropyridine-4-carboxylic acids at 180-200 ° C. The accurate determination of the melting point is of great significance to determine its purity and characteristics. In the synthesis and purification process, the melting point is a key indicator. < Br > Solubility, slightly soluble in water, slightly better solubility in polar organic solvents (such as methanol, ethanol, acetone, etc.). This property is very important in separation, purification and reaction medium selection. According to its solubility, a suitable solvent can be selected to promote the smooth progress of the reaction, or to achieve effective product separation.
    Density is relatively stable, near a specific value. Density data provide reference for product storage, transportation and process design, such as material transportation, mixing, etc. Density is an important consideration.
    In addition, 2% 2C3-dihydropyridine-4-carboxylic acid has good stability and can be stored for a long time without significant deterioration under conventional conditions, but under extreme conditions such as high temperature, strong acid and alkali, the structure may change. Understanding these physical properties is crucial for their applications in organic synthesis, drug discovery, materials science, and other fields, and helps researchers and engineers better control the relevant processes and achieve the desired results.
    What is the market price of 2,3-dichloropyridine-4-boronic acid?
    In today's market, the price of 2,3-dihydroxybutyric acid-4-lactone often varies depending on quality, supply and demand. A good product, its quality is pure and effective, and the price is also high; if the quality is slightly inferior, the price is slightly reduced.
    And the number of supply and demand has a great influence on the price. If there are many applicants and few suppliers, the price will rise; if the supply exceeds the demand, the price will decline. And the origin is different, and the method of procurement may be different, which can also make the price difference.
    Generally speaking, in today's market, the price of 2,3-dihydroxybutyric acid-4-lactone is about tens to hundreds of dollars per gram. However, this is only an approximation, and the actual price must be consulted in detail with the merchants of the pharmaceutical restaurant, which changes from time to time and varies from situation to situation. If you want to get a definite price, you must visit it in person to know its truth.
    What are the precautions for storing and transporting 2,3-dichloropyridine-4-boronic acid?
    2% 2C3-diethoxysuccinic acid-4-lactone needs to pay attention to many key matters during storage and transportation.
    First, this material is extremely sensitive to temperature. Its properties may change abnormally at either too high or too low temperatures. High temperature is easy to decompose. If the temperature far exceeds the appropriate range, it may cause internal structure changes, resulting in quality damage. Low temperature should not be underestimated, or the shape of the material changes, such as crystallization, solidification, etc., affecting subsequent use. Therefore, it should be stored in a cool, ventilated and temperature stable place, usually 2-8 ° C.
    Second, moisture resistance is essential. This substance has a certain degree of hygroscopicity and is prone to hydrolysis and other reactions in contact with water. Once damp, it will not only change its chemical composition, but also reduce its purity and even cause failure. When storing, be sure to ensure that the environment is dry, the packaging is well sealed, and a desiccant can be added to assist in moisture prevention.
    Third, shock resistance is indispensable during transportation. Because it is a relatively fragile organic compound, the internal structure may be damaged under turbulent vibration. The transportation vehicle should run smoothly, avoid violent actions such as sudden braking and sharp turning, and the packaging should also be properly wrapped with materials with good shock resistance, such as foam and sponge.
    Fourth, pay attention to avoid mixing with other chemicals. 2% 2C3-diethoxysuccinic acid-4-lactone may chemically react with certain substances, causing danger. Such as strong oxidants, strong acids and bases, etc., must be isolated from them to prevent accidents.
    Fifth, whether it is storage or transportation, it must be clearly marked. Indicate the name, nature, dangerous precautions, etc., so that relevant personnel can see at a glance, operate correctly, and avoid risks.