2 3 Dichloro 5 Nitropyridine
pyridine pyrrole pyrazine piperidine piperazine

2,3-Dichloro-5-nitropyridine

    Specifications

    HS Code

    594178

    Chemical Formula C5H2Cl2N2O2
    Molar Mass 193.0 g/mol
    Appearance Yellow solid
    Melting Point 74 - 78 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents like dichloromethane
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Hazard Harmful if swallowed, inhaled or in contact with skin

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    General Information
    Where to Buy 2,3-Dichloro-5-nitropyridine in China?
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    Frequently Asked Questions

    As a leading 2,3-Dichloro-5-nitropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3-dichloro-5-nitropyridine?
    2% 2C3-dideuterium-5-nitropyridine, which was not known to the world in the era of Tiangong Kaiwu, so it is difficult to answer according to the style of Tiangong Kaiwu. However, in terms of today's chemical knowledge, its use is quite extensive.
    In the field of organic synthesis, it is often used as a key intermediate. Due to the presence of nitro groups in its structure, it gives it unique reactivity. Nitro can be converted into amino groups by reduction, laying the foundation for the synthesis of nitrogen-containing functional materials and drugs. For example, when preparing some pyridine drugs with specific pharmacological activities, 2% 2C3-dideuterium-5-nitropyridine can gradually build complex drug molecular structures through a series of reactions, introducing other functional groups.
    In the field of materials science, due to its deuterium content, materials can have special physical properties. After deuterium atoms replace hydrogen atoms, they can change the molecular vibration frequency, etc., which in turn affects the optical and electrical properties of materials. For example, when developing new photoelectric materials, the use of its unique structure is expected to improve the stability and luminous efficiency of materials.
    In addition, in chemical research, it can also be used for isotope tracing experiments. By tracing the whereabouts of deuterium atoms in the reaction system, the chemical reaction mechanism was deeply explored, providing key information for optimizing the reaction path and improving the reaction yield.
    What are the synthesis methods of 2,3-dichloro-5-nitropyridine?
    There are several common methods for the synthesis of 2% 2C3-difluoro-5-formylpyridine:
    One is to use pyridine derivatives as starting materials. A suitable pyridine compound can be taken first, and fluorine atoms can be introduced under specific reaction conditions. This process often requires the help of specific fluorination reagents, such as fluorine-containing halides, etc., under the action of appropriate catalysts, the substitution of fluorine atoms to hydrogen atoms at the corresponding positions is realized. Then, through suitable oxidation or other functional group conversion reactions, formyl groups are constructed at the 5th position of the pyridine ring. For example, oxidation reactions catalyzed by some metal catalysts can be used to convert the corresponding substituents into formyl groups.
    Second, the pyridine ring can be constructed from a simple organic small molecule through a multi-step reaction. First, a suitable small molecule containing carbon, nitrogen, fluorine and other elements is used as raw materials to form a pyridine ring skeleton through condensation, cyclization and other reactions. In the process of constructing the pyridine ring, the reaction steps are reasonably designed so that fluorine atoms and formyl groups are introduced precisely at the expected 2,3 and 5 positions. This path requires strict control of the reaction conditions to ensure the selectivity and yield of each step.
    Third, a cross-coupling reaction strategy catalyzed by transition metals can also be used. Select fluorinated halogenated aromatics or other fluorine-containing active intermediates, and a substrate containing a pyridine ring with a suitable reaction check point. Under the action of transition metal catalysts such as palladium and nickel, the fluorine atoms are connected to the 2,3 positions of the pyridine ring through cross-coupling reaction. After that, a formyl group is introduced at the 5 position through subsequent reactions. This method requires high activity and selectivity of the catalyst, and the reaction conditions such as reaction solvent and base need to be optimized to achieve the best reaction effect.
    What are the physical and chemical properties of 2,3-dichloro-5-nitropyridine?
    2% 2C3-dihydro-5-cyanopyridine, this is an organic compound. Its physical and chemical properties are quite important and are related to many fields of application.
    Looking at its physical properties, under normal conditions, it may be a solid state, but the specific state is closely related to temperature and pressure. Melting point and boiling point are also key characteristics. Melting point indicates the temperature at which a substance transitions from solid to liquid state, and boiling point indicates the temperature at which it transitions from liquid to gaseous state. These two determine its existence form under specific conditions. Density is related to the mass per unit volume and has important guidelines for the measurement and application of substances.
    In terms of chemical properties, the presence of cyanyl groups in 2% 2C3-dihydro-5-cyanopyridine confers specific reactivity. Cyanyl groups can participate in various reactions, such as hydrolysis. Under suitable conditions, cyanyl groups can be converted into carboxyl or amide groups. It can also participate in nucleophilic substitution reactions. Due to the electron-absorbing properties of cyanyl groups, the electron cloud density on the pyridine ring can be changed, which affects the reactivity at other positions on the ring.
    Furthermore, the double bonds in this compound are also a check point for reactivity. The double bonds can undergo addition reactions and react with reagents such as hydrogen halides and halogens to form new compounds. This is an important means for building complex structures in organic synthesis. And the chemical stability of 2% 2C3-dihydro-5-cyanopyridine also needs to be considered. Its stability under different environments, such as acids, bases, and redox conditions, affects its storage and use.
    In short, the physical and chemical properties of 2% 2C3-dihydro-5-cyanopyridine lay the foundation for its application in organic synthesis, materials science, and drug development. Only by understanding its properties can it be better utilized.
    What is the price range of 2,3-dichloro-5-nitropyridine on the market?
    Today there are 2,3-dihydro-5-cyanopyridine, what is the price in the market? The price of all things in the market varies with time, place and quality. This 2,3-dihydro-5-cyanopyridine is no exception.
    If its quality is pure and excellent, produced in a famous factory, with excellent craftsmanship and no impurities, in the prosperous city of Dayi, the price per gram may be in the tens of gold when supply and demand are balanced. If in a remote place, the price may be slightly higher, and each gram can reach about 100 gold.
    However, if the quality is inferior and contains more impurities, although the price is cheap, it will be disadvantageous to the user. And the market situation is impermanent, sometimes the supply exceeds the demand, and the price will drop; sometimes the demand exceeds the supply, and the price will rise.
    Also, the amount of purchase is also related to the price. If you buy in bulk, the merchant may promote the sale, and the price per gram may be reduced by a few gold.
    Therefore, if you want to know the exact price, you should consult the merchants in the market, or visit the platforms of chemical materials trading, and observe the changes in the current price, measure the quality and quality, and the amount required to obtain the exact price.
    What are the storage conditions for 2,3-dichloro-5-nitropyridine?
    2% 2C3-difluoro-5-chloropyridine is an extremely rare and versatile chemical substance, and its storage conditions need to be extremely cautious. "Tiangong Kaiwu" does not directly describe its storage conditions, but according to the wisdom of the ancients on the preservation of chemical substances and the storage of related substances, the following inferences can be made.
    First, it should be placed in a cool place. This substance may be quite sensitive to temperature, and high temperature can easily cause it to undergo chemical reactions, resulting in changes in its properties. For example, "Tiangong Kaiwu" often mentions avoiding direct sunlight and high temperature environments in the preservation of many materials, because high temperature will cause materials to deteriorate. Therefore, 2% 2C3-difluoro-5-chloropyridine should also be stored in a cool place under the sun to prevent it from changing due to high temperature.
    Second, it needs to be kept dry. Many chemicals are prone to hydrolysis and other reactions in contact with water, and the same is true for 2% 2C3-difluoro-5-chloropyridine. When the ancients preserved salts, alkalis and other substances, they paid attention to moisture prevention. They were stored in sealed containers such as urns and cylinders and placed in dry places. This substance should also be stored in a well-sealed container and stored in a dry environment to avoid deterioration caused by water vapor erosion.
    Third, it should be kept away from fire sources and strong oxidants. This substance may be flammable to a certain extent or can react violently with strong oxidizing agents. In "Tiangong Kaiwu", there are many mentions of the prevention of flammable and explosive substances, emphasizing the isolation of fire sources. 2% 2C3-difluoro-5-chloropyridine should also be stored away from fire sources, and should not be mixed with strong oxidizing agents to prevent accidents.
    Fourth, the storage place should be well ventilated. Even if it is sealed and stored, a very small amount of substances may evaporate. If the ventilation is poor, the volatile gas will accumulate, or the concentration will be too high, causing danger. The ancients also paid attention to ventilation in storage places to ensure safety. Therefore, the storage of 2% 2C3-difluoro-5-chloropyridine requires good ventilation conditions to disperse the volatile gas in time.