2 3 Dichloro 4 Formylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2, 3-Dichloro-4-formylpyridine

    Specifications

    HS Code

    251773

    Chemical Formula C6H3Cl2NO
    Molar Mass 176.00 g/mol
    Appearance Solid (usually)
    Color May be off - white to light - colored
    Odor Typically has a characteristic chemical odor
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
    Melting Point Specific value depends on purity, but generally in a certain range
    Boiling Point Would have a boiling point relevant to its molecular structure and intermolecular forces
    Density A density value related to its mass - volume relationship
    Stability Stable under normal conditions but can react with certain reagents
    Hazard Class May be classified as a hazardous chemical due to potential toxicity and reactivity

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    General Information
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    Frequently Asked Questions

    As a leading 2, 3-Dichloro-4-formylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2,3-dichloro-4-formylpyridine?
    2% 2C3 + - + dioxy + - + 4 + - + methylbenzylpyridine, this substance is called vitamin B6, and its main use is wide.
    In the field of medicine, it can be used as an agent for the prevention and treatment of various diseases. First, it can effectively prevent and treat peripheral neuritis, insomnia, and restlessness caused by large or long-term application of isoniazid, hydrazine, etc.; reduce nausea, vomiting, or pregnancy vomiting caused by anticancer drugs and radiotherapy. Second, convulsions in infants or given to pregnant women can prevent convulsions in infants. Third, in the treatment of anemia, vitamin B6 participates in the conversion of tryptophan to niacin or 5-hydroxytryptamine. When deficient, it can cause anemia, and supplementation can help relieve
    In the food industry, vitamin B6 is an important nutrient enhancer. Because it is one of the essential vitamins for the human body, in many food processing processes, an appropriate amount of vitamin B6 will be added to increase the nutritional value of the food and meet the daily needs of the human body for this vitamin. It is commonly found in bakery such as bread and biscuits, as well as various infant and young child foods.
    In the field of feed, vitamin B6 is also indispensable. During the growth process of animals, vitamin B6 is also required to maintain normal physiological functions. Adding it to feed can promote animal growth and development, improve animal immunity, and ensure the healthy growth of animals, which is of great significance to the development of animal husbandry.
    What are the synthesis methods of 2,3-dichloro-4-formylpyridine?
    The synthesis methods of 2% 2C3-dioxo-4-methylbenzylpyridine generally include the following:
    First, the corresponding starting material is obtained by nucleophilic substitution reaction. The compound with active halogen atom and the nucleophilic reagent containing pyridine structure are selected in a suitable solvent, supplemented by the catalysis of base, so that nucleophilic substitution occurs. In this process, the polarity of the solvent, the strength and dosage of the base all have a great influence on the reaction. If the polarity of the solvent is suitable, it can promote the formation and stability of the ionic intermediate and accelerate the reaction process; too much or too little base may cause the reaction rate to change and even affect the selectivity of the product.
    Second, the cyclization reaction strategy is adopted. The compound containing the cyclized structural unit is used as the starting material, and the pyridine ring structure is constructed by the reaction in the molecule. During the reaction, the temperature and the type of catalyst are crucial. If the temperature is too low, the reaction is difficult to start; if the temperature is too high, it may initiate side reactions. The specific catalyst can reduce the activation energy of the reaction and guide the reaction towards the target product.
    Third, it is synthesized through the coupling reaction catalyzed by transition metals. Transition metal catalysts can activate substrate molecules and promote the formation of carbon-carbon and carbon-heteroatomic bonds. In such reactions, the ligand of metal catalysts has a significant impact on the activity and selectivity of the reaction. Different ligands can change the electron cloud density and steric resistance in the metal center, thereby regulating the reaction path and improving the yield of the target product.
    Fourth, the synthesis is achieved by using oxidation reaction. The raw material with a specific structure is converted into the target product through the oxidation process. During the reaction, the oxidation ability of the oxidant needs to be precisely controlled. If the oxidation ability is too strong, it is easy to over-oxidize, causing the product to decompose or form other by-products; if the oxidation ability is insufficient, the reaction cannot be carried out completely, which affects the purity and yield of the product.
    All synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to make a careful choice according to the availability of raw materials, the controllability of reaction conditions, the purity and yield requirements of the product, and many other factors.
    What are the physical properties of 2,3-dichloro-4-formylpyridine
    2% 2C3 + - + dioxy + - + 4 + - + methylbenzylpyridine, this physical property is special. Its color may be colorless to pale yellow transparent, and it is liquid in nature. If it has a taste, it is also slightly specific.
    Looking at its boiling degree, it is quite impressive, usually boiling in a specific temperature range, which is determined by its attractive force and structure between molecules. Its melting degree is relatively low, and it is easy to form a liquid phase flow state when it encounters a little temperature change.
    When it comes to solubility, it is well soluble in many organic solvents. Such as ethanol and ether, it can be mutually soluble with it and blend seamlessly. This is due to the similarity and miscibility principle between molecules. However, in water, the solubility is quite limited, and the polarity of water and its molecules is different, making it difficult to dissolve into each other.
    In addition, its density also has characteristics, slightly lighter than water. If placed in water, it often floats on it. And it has a certain volatility. In the open environment, it gradually evaporates over time and escapes in the air.
    As for chemical activity, the functional groups contained in its structure give it specific reactivity. Under suitable conditions, it can react with a variety of reagents, or add or replace, depending on the reaction conditions and the properties of the reagents.
    Such physical properties are useful in chemical, pharmaceutical and other industries. In the chemical industry, it can be used as a raw material to produce a variety of products through a series of reactions; in medicine, it can be used as a key intermediate to assist in the formation of molecules for drug efficacy.
    What are the chemical properties of 2,3-dichloro-4-formylpyridine
    2% 2C3 + - + dioxy + - + 4 + - + methylbenzylpyridine, this substance is an organic compound. Its chemical properties are as follows:
    First, it is basic. The nitrogen atom on the pyridine ring has an unshared electron pair and can accept protons, so it is basic and can react with acids to form salts. In case of hydrochloric acid, the corresponding hydrochloric acid will be generated. In organic synthesis, this property is often used to separate and purify compounds containing pyridine structures.
    Second, electrophilic substitution reaction. The pyridine ring is an electron-deficient aromatic ring, and the electrophilic substitution reaction activity is lower than that of the benzene ring, and the substituent group enters the 3 position. Under certain conditions, it will undergo a halogenation reaction with a halogenating agent to generate 3-halo-2,3-dioxy-4-methylbenzylpyridine.
    Third, oxidation reaction. The pyridine ring is relatively stable, and the methyl group of the side chain can be oxidized. Under the action of strong oxidants, methyl can be gradually oxidized to carboxyl groups. If the conditions are suitable, pyridine derivatives containing carboxyl groups can be obtained.
    Fourth, coordination ability. Because nitrogen atoms have lone pairs of electrons, this substance can be used as a ligand to coordinate with metal ions to form complexes. This is of great significance in the field of catalysis, and the formed complexes can be used as catalysts to catalyze some chemical reactions.
    What are the precautions for storing and transporting 2,3-dichloro-4-formylpyridine?
    2% 2C3 + - + dioxy + - + 4 + - + methylphenyl ether in storage and transportation, when careful attention to all things, security is safe.
    First heavy material characteristics. 2,3 - dioxy - 4 - methylphenyl ether, or with specific chemical activity and physical properties. It may be sensitive to external factors such as heat, light, and air. Therefore, when storing, it is advisable to choose a cool, dry and well-ventilated place, avoid direct sunlight and high temperature, and prevent deterioration, decomposition, or even dangerous chemical reactions caused by environmental discomfort.
    The second is the packaging material. The packaging must be solid and sealed to prevent the intrusion of external factors. The packaging materials used should be compatible with 2,3-dioxy-4-methylphenyl ether and do not chemically react with it. For example, if a plastic container is used, it is necessary to ensure that the plastic will not be corroded or swollen by this substance, otherwise it may leak and endanger safety.
    When transporting, also be cautious. Vehicles should be clean and dry, and there are no other substances that may react with them. During transportation, strictly prevent moisture, rain, and severe vibration and collisions to prevent package damage. And transportation personnel must be professionally trained to be familiar with the dangerous characteristics of this substance and emergency treatment methods. In case of emergencies, they can respond quickly and properly.
    In addition, regardless of storage or transportation, they should comply with relevant regulations and standards. Do a good job of marking, clearly indicating the name of the substance, hazard characteristics and other key information for identification and supervision. And establish complete records, indicating the time, quantity, flow and other details of storage and transportation, for traceability and inquiry. In this way, the safety of 2,3-dioxy-4-methylphenyl ether during storage and transportation must be ensured.