2 3 Dibromopyridine
pyridine pyrrole pyrazine piperidine piperazine

2,3-dibromopyridine

    Specifications

    HS Code

    681063

    Name 2,3 - dibromopyridine
    Molecular Formula C5H3Br2N
    Molecular Weight 250.9
    Appearance White to off - white solid
    Melting Point 54 - 56 °C
    Boiling Point 245 - 247 °C
    Density 2.125 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point 102.3 °C
    Cas Number 5349 - 26 - 4

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    Frequently Asked Questions

    As a leading 2,3-dibromopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3-dibromopyridine?
    2% 2C3-dibromopentane is an organic compound with a wide range of uses in the field of organic synthesis. Its main uses are as follows:
    First, as a key intermediate in organic synthesis. Because its molecule contains bromine atoms, it is chemically active and can participate in many chemical reactions, such as nucleophilic substitution reactions. With this, various functional groups can be introduced to lay the foundation for the synthesis of complex organic compounds. When preparing alcohols with a specific structure, the bromine atom in 2% 2C3-dibromopentane can be replaced by hydroxyl groups to obtain the target product. At the same time, it also plays an important role in the construction of carbon-carbon bonds. For example, by reacting with organometallic reagents, it can achieve the growth of carbon chains and the expansion of structures, which can help to synthesize organic compounds with different carbon skeletons.
    Second, it is used in the field of materials science. Polymer materials with special properties can be prepared by appropriate chemical modification and polymerization of 2% 2C3-dibromopentane. In the synthesis of some functional polymers, 2% 2C3-dibromopentane is used as a starting material. After the polymerization process, the material is endowed with unique properties, such as flame retardancy and thermal stability, which in turn meets the specific needs of different fields for material properties.
    Third, it is also used in pharmaceutical chemistry research. In the design and synthesis of new drug molecules, 2% 2C3-dibromopentane can be introduced into the drug molecule as a structural fragment, changing the physicochemical properties and biological activities of the drug. Through rational molecular design and reaction strategies, using its chemical activity, a library of compounds with potential biological activity is constructed, providing a material basis for screening new drugs with high efficiency and low toxicity.
    What are the synthesis methods of 2,3-dibromopyridine?
    There are many methods for synthesizing 2% 2C3-dibromothiophene, the following are common methods:
    First, thiophene is used as the starting material and obtained by bromination reaction. In an appropriate reaction solvent, such as glacial acetic acid, dichloromethane, etc., thiophene is reacted with bromine under specific conditions. Usually an appropriate amount of catalyst, such as iron powder, iron tribromide, etc., can be added to promote the reaction. Pay attention to control the reaction temperature during the reaction to avoid excessive bromination. Generally speaking, the reaction at low temperature (such as 0-10 ° C) is more conducive to the formation of 2-bromothiophene, and the appropriate increase in temperature (such as 20-30 ° C) can promote the formation of 2% 2C3-dibromothiophene. After the reaction is completed, it is washed with water and alkaline to remove unreacted bromine and by-products, and then the product is purified by distillation and recrystallization.
    Second, the reaction involving metal-organic reagents is used. For example, first make thiophene into the corresponding lithium reagent or magnesium reagent, such as thiophene lithium or thiophene Grignard reagent. Taking thiophene lithium as an example, thiophene can be obtained by reacting thiophene with butyllithium in a low temperature and anhydrous and oxygen-free environment. Then, lithium thiophene is reacted with brominated reagents (such as copper bromide, zinc bromide, etc.) to achieve the introduction of bromine atoms on the thiophene ring. By skillfully controlling the reaction conditions and the amount of reagents, 2% 2C3-dibromothiophene can be obtained. The advantage of this method is that the selectivity of the reaction is relatively high, and there are few side reactions. However, the reaction equipment and operation requirements are relatively strict, and the conditions of anhydrous and anaerobic conditions need to be strictly controlled.
    Third, the coupling reaction catalyzed by transition metals can be used. Suitable transition metal catalysts, such as palladium catalysts (such as tetra (triphenylphosphine) palladium, etc.), can be selected with corresponding ligands. Using halogenated thiophene derivatives as substrates and brominated reagents in the presence of bases, this method can precisely construct carbon-bromine bonds, and can achieve efficient synthesis of the target product 2% 2C3-dibromothiophene by adjusting the substrate and reaction conditions. However, transition metal catalysts are often expensive and post-reaction treatment is relatively complicated, so the recovery and residue of catalysts need to be considered.
    Different synthesis methods have their own advantages and disadvantages. In practical applications, the appropriate synthesis route needs to be reasonably selected according to many factors such as specific needs, availability of raw materials, cost and equipment conditions.
    What are the physical properties of 2,3-dibromopyridine?
    2% 2C3-diynylbenzene is an organic compound with special physical properties. It is colorless to pale yellow liquid and stable at room temperature and pressure, but in case of open flame, hot topic or strong oxidant, there is a risk of combustion and explosion.
    When it comes to solubility, 2% 2C3-diynylbenzene is insoluble in water, but soluble in most organic solvents, such as ethanol, ether, benzene, etc. This property makes it commonly used as a solvent or reaction intermediate in the field of organic synthesis.
    The melting point of this compound is about -30 ° C, and the boiling point is about 200-205 ° C. The melting boiling point characteristic makes it convenient to realize the phase transition under specific temperature conditions, which provides convenience for related experimental operations and industrial production.
    2% 2C3-dialkynylbenzene has a density of about 1.05-1.10 g/cm ³, which is slightly greater than that of water. Its vapor pressure is low and volatility is relatively small.
    From the perspective of molecular structure, 2% 2C3-dialkynylbenzene contains conjugated alkynyl groups and benzene ring structures. The conjugated system gives it unique electronic properties, which makes it show potential application value in the fields of optics and electricity. For example, it can be used to prepare organic optoelectronic materials to achieve efficient charge transfer and photoelectric conversion through conjugated structures.
    In addition, 2% 2C3-dialkynylbenzene has high chemical activity, and the alkynyl group can undergo a variety of chemical reactions, such as nucleophilic addition, cyclization, etc. This reactivity makes it a key raw material for building complex molecular structures in organic synthesis.
    What is the market price of 2,3-dibromopyridine?
    What is the market price of 2% 2C3-dihydroxynaphthalene? This is a question related to business. However, it is not easy to determine the price. The change of prices depends on multiple ends.
    One is the state of supply and demand. If there are many people who want 2% 2C3-dihydroxynaphthalene, but there are few people who produce it, the price will increase; on the contrary, if the supply exceeds the demand, the price will decline.
    Second, the cost of production. The collection of materials, labor, equipment, and the improvement of technology all involve costs. If the material is rare and difficult to harvest, the labor cost is high, and the technology is demanding, the production cost will increase, and the price will also rise.
    Third, the competition for the market. There are many merchants competing to attract customers, or to reduce prices in order to sell; if there are no competitors, merchants may bid higher prices.
    Fourth, the regulations of the government. The tax and subsidy policies of the government can also affect the price. If the tax is heavy, the price will be changed; if the price is higher, the producer may reduce the price in order to compete for the market.
    It is difficult to determine the exact price of 2% 2C3-dihydroxynaphthalene without knowing the details of its supply and demand, product fees, competition status, and political regulations. If you want to know its price, you can visit the chemical industry market, consult the merchants, or check the market's newspapers and research reports to get a more accurate price.
    What are the precautions for storing and transporting 2,3-dibromopyridine?
    When storing and transporting 2% 2C3-dibromopentane, many things need to be paid attention to.
    The first thing to pay attention to is its chemical properties, which are halogenated hydrocarbons and have certain chemical activity. When storing, it should be placed in a cool and well-ventilated warehouse, away from fire and heat sources. It may cause dangerous reactions due to heat or open flames. The temperature of the warehouse should not be too high to prevent it from accelerating its decomposition or triggering other chemical reactions.
    Furthermore, it is harmful to the human body because of its toxicity and irritation. Storage and transportation personnel must take protective measures, such as wearing suitable protective gloves, protective glasses and gas masks, to avoid contact or inhalation and cause damage to the body.
    At the same time, the substance should be stored separately from oxidizing agents, alkalis, etc., and must not be mixed in storage and transportation. Due to its contact with oxidizing agents, or violent oxidation reactions; encounters with alkalis, or chemical reactions such as hydrolysis, may cause danger.
    During transportation, ensure that the container is well sealed to prevent leakage. The transportation tools selected should also meet relevant safety standards to avoid damage to the container due to bumps and collisions during transportation. If a leak occurs, it should be dealt with immediately in accordance with established emergency treatment procedures, evacuate surrounding personnel, and properly collect and deal with the leak to prevent environmental pollution.
    The storage and transportation of 2% 2C3-dibromopentane requires strict compliance with relevant safety regulations and operating procedures, and comprehensive protection and management work to ensure safety.