2 3 Dibromo 6 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2,3-Dibromo-6-(trifluoromethyl)pyridine

    Specifications

    HS Code

    825412

    Chemical Formula C6H2Br2F3N
    Molecular Weight 318.89
    Solubility In Water Low solubility expected due to non - polar nature
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Vapor Pressure Low vapor pressure expected for a non - volatile compound
    Reactivity Reactive towards nucleophiles due to the presence of bromine atoms and electron - withdrawing trifluoromethyl group

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    General Information
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    Frequently Asked Questions

    As a leading 2,3-Dibromo-6-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3-dibromo-6- (trifluoromethyl) pyridine?
    2% 2C3 -dibromo-6- (triethylmethyl) pyridine, which is widely used. In the field of pharmaceutical synthesis, it is often used as a key intermediate and can be used to prepare a variety of drugs with specific biological activities. For example, when developing specific drugs for certain diseases, with its unique chemical structure, it can precisely bind to specific biological targets, and then exert therapeutic effects.
    In the field of materials science, it also has important uses. For example, when synthesizing some functional polymer materials, it can participate in the polymerization reaction as a reactive monomer, giving the material unique properties such as good thermal stability and optical properties, making the material stand out in the fields of electronic devices, optical instruments, etc.
    In the field of organic synthetic chemistry, 2% 2C3-dibromo-6- (triethylmethyl) pyridine is often used as a key building block in organic synthesis, with the help of various functional group conversion reactions to construct complex organic molecular structures, providing organic synthesis chemists with an extremely effective synthesis tool to help them create more novel and complex organic compounds.
    What are the synthesis methods of 2,3-dibromo-6- (trifluoromethyl) pyridine?
    To prepare 2,3-dibromo-6- (triethyl) pyridine, there are several methods:
    First, pyridine is used as the starting material, triethyl is introduced through a specific substitution reaction, and then bromination is carried out at an appropriate position. This process requires fine control of the reaction conditions, such as temperature, reagent ratio, etc., in order to improve the yield and purity of the target product. Due to the electron cloud distribution characteristics of the pyridine ring, the substitution reaction check point is selective, and only precise regulation can achieve the desired effect.
    Second, pyridine derivatives containing triethyl can be prepared first, and then bromine atoms can be introduced through halogenation reaction. The key to this path lies in the synthesis of precursor derivatives, which needs to be achieved through multi-step reactions, each step is related to the quality of the final product. The activity and reaction sequence of the reagents involved in the reaction need to be carefully considered. If there is a slight error, side reactions will occur and the product generation will be affected.
    Third, the coupling reaction catalyzed by transition metals. First, a suitable intermediate containing triethyl methyl and bromide atoms is prepared, and then the coupling is carried out under the action of transition metal catalysts. The advantage of this method is that the reaction is highly selective, which can effectively avoid unnecessary side reactions. However, transition metal catalysts are expensive, and the reaction conditions are harsh, which requires high requirements for reaction equipment and operation. In actual production, the cost and benefit need to be weighed.
    There are various methods for preparing 2,3-dibromo-6- (triethylmethyl) pyridine, each with its own advantages and disadvantages. Experimenters should choose the optimal route according to their own conditions, target product requirements and other factors, so as to achieve the purpose of efficient and economical synthesis.
    What are the physical properties of 2,3-dibromo-6- (trifluoromethyl) pyridine?
    2% 2C3-dibromo-6- (triethylmethyl) pyridine, which has many physical properties. It is mostly in solid form at room temperature, and it may be white to pale yellow crystalline powder. The appearance is fine and the texture is uniform.
    As far as the melting point is concerned, it has been experimentally determined to be roughly in a certain temperature range. The melting point is an important physical property of the substance, and its purity and category can be preliminarily determined. The exact value of the melting point of this substance is of great significance for the subsequent synthesis, separation and identification processes.
    When it comes to solubility, it shows a certain solubility in common organic solvents such as ethanol and acetone. In ethanol, after stirring, it can be partially dissolved to form a homogeneous solution, indicating that there is an interaction between it and ethanol molecules, or due to van der Waals forces, hydrogen bonds and other forces. However, in water, its solubility is poor, which is mainly due to the large proportion of hydrophobic groups in the molecular structure of the substance, which makes it difficult to form effective interactions with water molecules, and is more inclined to agglomerate among its own molecules.
    In addition, the density of the substance is also a key physical property. Through accurate measurement, its density data under specific conditions can be obtained. Density is not only related to the relationship between the mass and volume of the substance, but also an important consideration in practical applications such as material transportation and storage. If the density is large, under the same volume, the mass is greater, and the load-bearing capacity of the load-bearing equipment needs to be considered when transportation and storage; conversely, if the density is small, the space occupied is relatively large.
    Its stability is also a physical property that cannot be ignored. When it is at room temperature and pressure without special external factors, the chemical properties of the substance are relatively stable, and it is not easy to spontaneously decompose or other chemical reactions. However, when encountering specific conditions such as high temperature and strong oxidants, the stability may be damaged, or reactions such as decomposition and oxidation may be triggered. Therefore, during storage and use, attention should be paid to avoiding such adverse conditions to ensure the stability of its physical and chemical properties, so as to ensure the safety and effectiveness of related operations.
    What is the market outlook for 2,3-dibromo-6- (trifluoromethyl) pyridine?
    There are currently 2,3-dibromo-6- (triethylmethyl) pyridine, and its market prospects are related to many aspects.
    Looking at its application in the field of medicine, it may have considerable prospects. Geinpyridine compounds are often key intermediates in drug synthesis. This 2,3-dibromo-6- (triethylmethyl) pyridine may be chemically modified to become antibacterial, anti-inflammatory, anti-tumor and other drugs. The demand for new drug intermediates is increasing with each passing day. If it can be developed and applied in this field, the market may be quite broad.
    There are also potential opportunities in materials science. Pyridine derivatives can be used to prepare functional materials, such as optoelectronic materials. The special structure of this compound may give the material unique optoelectronic properties. With the booming development of the electronics industry, the demand for new optoelectronic materials is on the rise. If we can develop characteristic materials based on this pyridine compound, we can gain a place in the market.
    However, its market development also faces challenges. The difficulty of chemical synthesis affects the cost. If the synthesis process is complicated and the cost is high, it may be difficult to be competitive in the market. And the market competition is fierce, similar or alternative products may have occupied part of the market share. To stand out, we need to show our advantages in performance, cost and other aspects.
    Overall, 2,3-dibromo-6- (triethylmethyl) pyridine has a certain market potential, but to fully exploit it, scientific research and industry need to work together to overcome synthesis problems and expand application fields in order to achieve good results in the market.
    What are the precautions for using 2,3-dibromo-6- (trifluoromethyl) pyridine?
    2% 2C3 -dibromo-6- (triethylmethyl) pyridine is an organic compound. During use, the following matters must be paid attention to:
    First, safety protection is essential. This compound contains bromine, or it may be toxic and corrosive. Users must wear appropriate protective equipment, such as protective gloves, goggles and protective clothing, to prevent skin contact and eye splashing. The operation should be carried out in a well-ventilated place, or even with the help of a fume hood, to avoid inhalation of its volatile aerosols. If you are inadvertently exposed, you should immediately rinse with plenty of water and seek medical treatment according to the specific situation.
    Second, storage conditions should not be ignored. Store it in a cool, dry and ventilated place, away from fire and heat sources, and avoid direct sunlight. Because of its chemical properties or more active, contact with certain substances or cause chemical reactions, it should be stored separately from oxidants, acids, bases, etc., and should not be mixed to prevent danger.
    Third, it is crucial to accurately control the dosage and reaction conditions when using it. Because of the chemical reaction it participates in or the strict requirements on the dosage and reaction temperature, time, solvent and other conditions. Improper dosage or poor control of conditions may not only cause the reaction effect to be less than expected, but also cause side reactions and form other impurities, which affect the purity and yield of the product. Before the reaction, the reaction mechanism and related conditions should be fully studied and tested to ensure accurate operation.
    Fourth, waste disposal must be in compliance. Residues after use and waste generated by the reaction cannot be discarded at will. Proper classification, collection and treatment should be carried out in accordance with relevant environmental regulations and laboratory regulations to prevent environmental pollution. Generally speaking, bromine-containing organic waste needs to be specially treated to reduce its harm to the environment.