2 3 Dibromo 5 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2,3-Dibromo-5-methylpyridine

    Specifications

    HS Code

    219726

    Chemical Formula C6H5Br2N
    Molecular Weight 250.92 g/mol
    Appearance Solid (Typical appearance description for such compounds)
    Solubility In Water Low (Aromatic brominated pyridines generally have low water solubility)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (Typical for such aromatic compounds)

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    General Information
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    Frequently Asked Questions

    As a leading 2,3-Dibromo-5-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3-dibromo-5-methylpyridine?
    2% 2C3-dibromo-5-methylpyridine, this substance has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize a variety of specific drugs. For example, in the preparation process of some antibacterial drugs, with their special chemical structures, they can participate in a series of chemical reactions, promoting the construction of antibacterial active ingredients, providing strong support for human resistance to bacterial infections.
    In terms of pesticides, it is also an important synthetic raw material. With the help of clever reactions with other chemicals, pesticide products with high insecticidal and bactericidal properties can be prepared. These pesticides can precisely combat various crop pests and pathogens, ensure the thriving growth of crops, thereby increasing food production and ensuring the stability and safety of food supply.
    In the field of materials science, 2% 2C3-dibromo-5-methylpyridine also plays a non-negligible role. It can be used to synthesize organic materials with unique properties, such as some materials with special optoelectronic properties. These materials have potential applications in electronic devices, optical devices, etc., and help to promote innovation and development in related fields.
    What are the synthesis methods of 2,3-dibromo-5-methylpyridine?
    To prepare 2,3-dibromo-5-methylpyridine, the method is as follows:
    First, 5-methylpyridine is used as the starting material. Shilling 5-methylpyridine and N-bromosuccinimide (NBS) in a suitable solvent, such as carbon tetrachloride, in the presence of an initiator, such as benzoyl peroxide, are heated to perform a radical substitution reaction, and bromine atoms are introduced into the 2-position of the pyridine ring to obtain 2-bromo-5-methylpyridine. Subsequently, this product is combined with liquid bromine under the catalysis of Lewis acid, such as iron tribromide, at a suitable temperature, such as 0 ° C to room temperature, so that the third position of the pyridine ring is reintroduced into a bromine atom, and the final result is 2,3-dibromo-5-methyl pyridine.
    Second, suitable pyridine derivatives can also be used as starting materials. For example, select a pyridine derivative with a substituent that can be converted into methyl and bromine atoms. First, the substituent that can be converted into methyl is converted into methyl through a specific reaction, such as alkylation reaction. Then, through a halogenation reaction, such as the use of a brominating agent, bromine atoms are gradually introduced at the 2nd and 3rd positions of the pyridine ring under appropriate conditions. Control the reaction conditions, such as reaction temperature, ratio of reactants and reaction time, to promote the reaction in the direction of generating 2,3-dibromo-5-methylpyridine. In this process, it is necessary to pay attention to the selectivity of the reaction and the occurrence of side reactions. If necessary, separation and purification operations can be carried out to obtain high-purity target products.
    Third, the strategy of constructing a pyridine ring through a multi-step reaction can also be considered. For example, a number of simple compounds containing nitrogen and carbon are used as raw materials to construct a pyridine ring through a series of reactions such as condensation and cyclization. In the process of constructing a pyridine ring, methyl and bromide atoms are introduced at suitable positions through rational design of reaction steps and selection of suitable reagents. Although this method is complicated, it can improve the selectivity and yield of the product to a certain extent. However, each step of the reaction requires fine control conditions, and the product separation and purification process is also complicated.
    What are the physical properties of 2,3-dibromo-5-methylpyridine?
    2% 2C3-dibromo-5-methylpyridine, which is an organic compound with special physical and chemical properties. Its properties are mostly crystalline, white or nearly colorless. The melting point is in a specific range, about [X] ° C. At this temperature, the solid-liquid phase transition is of great significance for its separation and purification. The boiling point is also characteristic, about [X] ° C. At this temperature, the substance vaporizes, which needs to be taken into account during distillation and other operations.
    In terms of solubility, it has a certain solubility in organic solvents such as ethanol and ether. This property is conducive to being used as a reactant or intermediate in organic synthesis, and the reaction environment is constructed with the help of organic solvents. However, the solubility in water is poor. Due to the large difference between the molecular polarity of the compound and the polarity of the water molecule, it follows the principle of "similar miscibility".
    From the perspective of chemical properties, the pyridine ring has aromatic properties, which endows it with certain stability. However, the bromine atom on the ring has considerable activity with methyl groups. Bromine atoms can undergo nucleophilic substitution reactions, such as reactions with nucleophiles containing hydroxyl groups and amino groups, to derive a variety of compounds, which broadens the path for organic synthesis. Methyl groups are affected by the pyridine ring, and α-hydrogen has a certain acidity. In a strong alkali environment, it can be captured, initiating a series of reactions, which are used to construct carbon-carbon bonds, etc., and are widely used in the construction of
    Due to its special properties, 2% 2C3-dibromo-5-methylpyridine plays a key role in the field of medicine and pesticides. In pharmaceutical research and development, it is used as an intermediate for the synthesis of drugs with specific structures; in the creation of pesticides, it participates in the synthesis of pesticides with high efficiency and low toxicity, making great contributions to human health and agricultural development.
    What is the market price of 2,3-dibromo-5-methylpyridine?
    I don't know the market price of 2,3-dibromo-5-methylpyridine. However, if you want to know the market value of this product, you should look at all the reasons.
    First, it depends on its supply and demand. If there are many people in the world who want it, but there are few products, the price will be high; on the contrary, if the supply exceeds the demand, the price will drop.
    Second, it is related to the difficulty of its production. If the preparation of 2,3-dibromo-5-methylpyridine requires complicated techniques and rare materials, the cost will be high, and its price will rise accordingly.
    Third, consider the competition in the market. If there are many producers, merchants compete for profits, competing for customers or reducing their prices; if there are few producers in the market, the price may be stable and high.
    Fourth, depending on the region. Different places have different prices due to taxes and freight. In places near the source of production, the price may be slightly lower; and far away, the price may increase due to freight, etc.
    To determine the market value of 2,3-dibromo-5-methyl pyridine, you can consult chemical raw material suppliers or check the platform for chemical product trading to get an accurate price.
    What are the storage conditions for 2,3-dibromo-5-methylpyridine?
    2% 2C3-dibromo-5-methylpyridine is an extremely important organic compound, which is widely used in many fields, such as medicine, pesticides, material science and other fields. Its storage conditions are related to its stability and quality, and caution is required.
    This compound should be stored in a cool and ventilated warehouse. Due to high temperature, it is easy to cause chemical reactions, causing it to decompose or deteriorate. Good ventilation can disperse harmful gases that may evaporate in time to avoid danger caused by their accumulation.
    Furthermore, keep away from fire and heat sources. 2% 2C3-dibromo-5-methylpyridine has the characteristics of flammability or easy decomposition by heat. In case of open flame and hot topic, it is easy to cause serious accidents such as combustion and explosion.
    At the same time, it should be stored separately from oxidants, acids, bases, etc., and should not be mixed. Due to its active chemical properties, severe chemical reactions may occur in contact with the above substances, and even cause danger.
    Keep the container sealed when storing. This can prevent it from contacting with moisture, oxygen and other substances in the air, avoid hydrolysis, oxidation and other reactions, and maintain its chemical stability.
    In addition, the warehouse needs to be equipped with suitable materials to contain leaks. In case of leakage, it can be dealt with in time and effectively to reduce pollution to the environment and harm to personnel.
    Strict control of the storage conditions of 2% 2C3-dibromo-5-methylpyridine is of vital significance to ensure its quality, ensure the safety of use and avoid adverse effects on the environment. During the storage process, relevant regulations and standards must be strictly followed and must not be slack.