2 3 Dibromo 5 Chloro Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2,3-Dibromo-5-Chloro Pyridine

    Specifications

    HS Code

    630751

    Chemical Formula C5H2Br2ClN
    Molecular Weight 272.34 g/mol
    Appearance Solid
    Color Off - white to light yellow
    Boiling Point Approx. 275 - 280 °C
    Melting Point 117 - 119 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Purity Typical Commercial 95%+
    Cas Number 6952-59-6
    Odor Weak, characteristic

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    General Information
    Where to Buy 2,3-Dibromo-5-Chloro Pyridine in China?
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    Frequently Asked Questions

    As a leading 2,3-Dibromo-5-Chloro Pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3-dibromo-5-chloropyridine?
    2% 2C3-dibromo-5-fluoropyridine has a crucial use in the field of chemical synthesis. The following details its main applications:
    First, in the synthesis of pharmaceutical chemistry, this compound is a key intermediate for the preparation of many specific drugs. For example, in the process of anti-tumor drug development, 2% 2C3-dibromo-5-fluoropyridine can participate in the construction of complex molecular structures. With its unique halogen atom activity, specific functional groups can be precisely connected by means of nucleophilic substitution reactions, and then molecular frameworks with specific pharmacological activities can be constructed. By reacting with nucleophiles containing nitrogen and oxygen, novel compounds with potential anti-tumor activities are generated, providing possible drug precursors for solving cancer problems.
    Second, in the field of pesticides, it also plays an indispensable role. It can be used as an important starting material for the synthesis of high-efficiency and low-toxicity pesticides. In view of the special chemical properties imparted by its fluorine atom and bromine atom, the synthesized pesticides not only have excellent insecticidal and bactericidal properties, but also reduce the adverse effects on the environment. For example, by reacting with the corresponding organic groups, insecticides targeting specific crop pests can be prepared, which can use their structural characteristics to precisely act on the physiological system of pests, effectively inhibit the growth and reproduction of pests, and ensure the healthy growth of crops.
    Thirdly, in the field of materials science, 2% 2C3-dibromo-5-fluoropyridine can be used to synthesize organic materials with special photoelectric properties. Due to the presence of halogen atoms in the structure, the electron cloud distribution of the material can be adjusted, thereby affecting its optical and electrical properties. For example, in the development of organic Light Emitting Diode (OLED) materials, the introduction of this compound can optimize the luminous efficiency and stability of the material, and promote the further development of display technology.
    In summary, 2% 2C3-dibromo-5-fluoropyridine, with its unique chemical structure, has shown important value in many fields such as medicine, pesticides, and materials science, and plays a key role in promoting technological innovation and development in related industries.
    What are the physical properties of 2,3-dibromo-5-chloropyridine?
    2% 2C3-dibromo-5-fluoropyridine is an organic compound with special physical properties. It is a solid at room temperature, and its appearance is often white to light yellow crystalline powder. Due to the orderly arrangement of molecular structures, the intermolecular forces make the substance appear solid, and the elements and structures contained determine the color.
    The melting point is about [X] ° C, which is determined by the intermolecular forces and crystal structure. The intermolecular forces are strong and require more energy to overcome to achieve the transition from solid to liquid, so the melting point is relatively stable, providing a basis for identification and purification.
    The boiling point is around [X] ° C. When the temperature reaches the boiling point, the molecule obtains enough energy to overcome the intermolecular forces and become gaseous. The boiling point is affected by the molecular weight, the type and strength of the intermolecular force. The mass is large and the force is strong, but the boiling point is high.
    2% 2C3-dibromo-5-fluoropyridine has a certain solubility in most organic solvents such as ethanol and acetone. Due to the principle of similar miscibility, its molecules have a certain polarity, and can form intermolecular forces with polar organic solvents, which is conducive to dissolution; but the solubility in water is poor. Due to the large difference between the polarity of water and the polarity of the compound, it is difficult to interact between molecules.
    In addition, the compound has a certain density, about [X] g/cm ³, which is determined by its molecular weight and the way of molecular accumulation. If the mass is large and the packing is tight, the density will be large, and the density is of great significance in material separation, identification and related process design.
    What are the synthesis methods of 2,3-dibromo-5-chloropyridine?
    The synthesis method of 2% 2C3-dibromo-5-fluoropyridine is a very important topic in the field of organic synthesis. There are many synthesis methods, and the following are common methods:
    First, halogenation method. This is to use pyridine as the initial raw material. First, nitro is introduced into the pyridine ring by nitration reaction, and then the nitro is converted into amino group by reduction. Then, the diazotization reaction is used to replace the amino group with a halogen atom to achieve the purpose of halogenation. In this process, the reaction conditions, such as temperature, reaction time, and the proportion of reactants, need to be carefully adjusted to improve the purity and yield of the product. For example, diazotization in a low temperature environment can effectively avoid the occurrence of side reactions. < Br >
    Second, metal catalytic coupling method. Using halogenated pyridine derivatives as substrates, with the help of metal catalysts, coupling reactions occur with corresponding halides or borate esters. Commonly used metal catalysts include palladium, nickel, etc. The advantage of this method is that the reaction is highly selective and the carbon-halogen bond can be precisely constructed. However, the cost of metal catalysts is high, and the reaction requires strict reaction conditions, such as anhydrous and anaerobic environments, to achieve the desired reaction effect.
    Third, cyclization method. With the help of suitable organic compounds, pyridine rings are constructed by intramolecular cyclization reaction, and bromine and fluorine atoms are introduced simultaneously. This method requires careful design of the structure of the reactants to ensure that the cyclization reaction can proceed smoothly. For example, the choice of compounds with specific functional groups, under suitable reaction conditions, prompts them to undergo intramolecular cyclization to generate the target product.
    To choose the most suitable synthesis method, it is necessary to comprehensively consider many factors, such as the availability of raw materials, cost, difficulty of reaction conditions, purity and yield of the product. Only in this way can the synthesis goal of high efficiency, economy and environmental protection be achieved.
    What is the market price of 2,3-dibromo-5-chloropyridine?
    In today's world, business conditions change, and in the market, the price of all kinds of goods often varies from time to time and place, and it is difficult to have a fixed number. As for the price of 2,3-dibromo-5-fluoropyridine, the market price is also determined by many factors.
    First, the situation of supply and demand is important. If there are many people in the world who need 2,3-dibromo-5-fluoropyridine, and the demand exceeds the supply, the price will rise; on the contrary, if the supply exceeds the demand and the stock is in the market, the price may drop.
    Second, the manufacturing cost is of great significance. From the purchase of its raw materials to the cost of various equipment and labor, it is all a cost. If the price of raw materials is high, and the cost of equipment and labor increases, the cost of making this product will be high, and its price in the market will not be low.
    Third, changes in the current situation and regulations of government orders also have an impact. If the world is flat, trade between states is smooth, and tariffs are simple, then its circulation is convenient, and the price may be stable; if it encounters soldiers, epidemics, or strict government orders, and trade is blocked, its price may change significantly.
    Fourth, competition in the industry also affects its price. There are many shops in the market that make this thing, and they compete to sell it at a good price. In order to compete for market profit, there may be a move to reduce the price; if there are few manufacturers, it will become a monopoly, and the price will be in their hands, which can be high or low.
    Therefore, if you want to know the price of 2,3-dibromo-5-fluoropyridine in the market, you must carefully observe the supply and demand, cost, current situation, and competition. In general, you can get a more accurate number, but it is difficult to have a constant price.
    What are the precautions for storing and transporting 2,3-dibromo-5-chloropyridine?
    2% 2C3-dibromo-5-fluoropyridine must pay attention to many key matters during storage and transportation.
    First storage conditions. This chemical substance should be stored in a cool, dry and well-ventilated place. Due to the cool environment, it can be avoided that the temperature is too high to cause its volatilization to accelerate or cause chemical reactions; drying can prevent it from interacting with water vapor, and some halogenated pyridines may be hydrolyzed in contact with water, which affects quality and stability; Good ventilation can disperse harmful gases that may escape and reduce safety risks. At the same time, it needs to be stored separately from oxidants, acids, bases, etc. Halogenated pyridine is chemically active, comes into contact with oxidants or has a violent oxidation reaction, interacts with acids and bases or causes structural changes and failures, and even causes danger. And the storage area should be equipped with materials suitable for containing and handling leaks, so as to deal with accidents in a timely manner.
    Secondary attention to transportation. Be sure to ensure that the container is sealed during transportation to prevent leakage. Because of its certain toxicity and volatility, leakage will pollute the environment and endanger the human body. Transportation vehicles should be equipped with corresponding fire and emergency treatment equipment, such as fire extinguishers, adsorption materials, etc., so that they can be dealt with quickly in emergencies. During transportation, keep away from fires and heat sources. Such substances are exposed to open flames, hot topics or have the danger of combustion and explosion. Drivers and escorts need to be specially trained, familiar with its nature and emergency handling methods, regularly check the integrity of the container and the status of the goods during transportation, strictly abide by the transportation regulations and routes, and do not stop in densely populated areas or areas with important facilities. In this way, the safety of 2% 2C3-dibromo-5-fluoropyridine in storage and transportation can be ensured, and accidents can be avoided.