2 3 Diaminopyridine
pyridine pyrrole pyrazine piperidine piperazine

2,3-diaminopyridine

    Specifications

    HS Code

    533964

    Chemical Formula C5H7N3
    Molar Mass 109.13 g/mol
    Appearance White to off - white solid
    Odor Odorless
    Melting Point 117 - 119 °C
    Boiling Point 300.2 °C at 760 mmHg
    Solubility In Water Soluble
    Solubility In Organic Solvents Soluble in ethanol, acetone, etc.
    Pka1 4.89
    Pka2 9.43
    Density 1.22 g/cm³

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    General Information
    Where to Buy 2,3-diaminopyridine in China?
    As a trusted 2,3-diaminopyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,3-diaminopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3-diaminopyridine?
    2% 2C3-dihydroxyacetophenone, also known as 3-hydroxytyrosol, has a wide range of uses. Its primary use lies in the field of medicine. Because of its antioxidant properties, it can scavenge free radicals in the human body, slow down oxidative damage to cells, and then prevent many chronic diseases, such as cardiovascular diseases and cancer. Modern medical research shows that it can reduce the content of cholesterol and triglycerides in the blood, improve vascular endothelial function, and reduce the risk of cardiovascular diseases. At the same time, it can inhibit the proliferation and metastasis of cancer cells, induce cancer cell apoptosis, and provide potential raw materials for the development of anti-cancer drugs.
    In the food industry, it also has an important position. Due to its antioxidant properties, it can be used as a food preservative to prolong the shelf life of food, prevent oxidative rancidity of oils, and maintain food flavor and quality. Adding this product to oily foods, meat products, and baked goods can significantly improve food stability and shelf life.
    In the cosmetics industry, its antioxidant and anti-inflammatory properties are also very popular. It can be added to skin care products to delay skin aging, reduce wrinkle formation, enhance skin elasticity, and at the same time have soothing and anti-inflammatory effects on sensitive skin, improving skin health.
    In addition, due to its unique chemical structure and biological activity, it can be used as an important intermediate in the field of organic synthesis for the synthesis of other organic compounds with special functions, providing assistance for the development of materials science, fine chemistry and other fields. In summary, 2% 2C3-dihydroxyacetophenone has an indispensable position in many fields such as medicine, food, cosmetics and organic synthesis due to its diverse functions.
    What are the synthesis methods of 2,3-diaminopyridine?
    2% 2C3-dihydroxyacetophenone, the synthesis method is quite diverse, and I will describe it in detail today.
    One is obtained by the acylation reaction of Fu-g with resorcinol as the starting material. This reaction requires Lewis acid such as anhydrous aluminum trichloride as the catalyst, and acetyl chloride or acetic anhydride as the acylation reagent. During the reaction, in a suitable organic solvent, such as dichloromethane, the resorcinol and the acylation reagent are slowly mixed at low temperature, and then the reaction is gradually heated. This process requires close attention to the control of the reaction temperature and time. If the temperature is too high or the time is too long, it may lead to the occurrence of polyacylation side reactions, which may affect the purity and yield of the product. < Br >
    The second one can be prepared from resorcinol and diethyl oxalate under the action of an alkaline catalyst, through the Dickman condensation reaction, and then through hydrolysis and decarboxylation. In this route, the choice of basic catalyst is very critical, and the commonly used bases such as sodium ethanol. The Dickman condensation reaction needs to be carried out in an anhydrous environment to ensure a smooth reaction. During the hydrolysis step, the reaction conditions need to be carefully controlled to prevent excessive hydrolysis. The decarboxylation reaction needs to choose an appropriate temperature and reaction time to achieve efficient conversion.
    Another method is to prepare 2% 2C3-dihydroxyacetophenone through hydroxylation reaction using o-hydroxyacetophenone as raw material. This reaction often requires the help of a specific oxidant and catalyst system, such as hydrogen peroxide as an oxidant, with a suitable metal catalyst, in a specific reaction medium. During the reaction, attention should be paid to the amount of oxidant, reaction temperature and catalyst activity to ensure that the hydroxylation reaction selectively occurs in the appropriate position and reduces the interference of other side reactions.
    The above synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively weigh and choose the best one according to the availability of raw materials, cost, difficulty in controlling reaction conditions, and purity requirements of the product.
    What are the physical properties of 2,3-diaminopyridine?
    2% 2C3-dihydroxyacetone is an important organic compound. Its physical properties are as follows:
    Under normal temperature and pressure, 2% 2C3-dihydroxyacetone is white to light yellow crystalline powder, fine in quality, and pure in appearance. This form is easy to store and transport, and is easy to use and operate in many application scenarios.
    When it comes to solubility, it has good solubility in water. Water can easily disperse 2% 2C3-dihydroxyacetone to form a uniform solution. This property makes it fully effective in many chemical reactions and industrial processes using water as a medium. Whether it is in the preparation of pharmaceutical preparations or in some biological experiments, good water solubility lays the foundation for its wide application. In addition to water, it also has certain solubility in organic solvents such as methanol and ethanol. In the field of organic synthesis, the use of organic solvents is extremely common. 2% 2C3-dihydroxyacetone can be soluble in such solvents, so that the relevant reactions can be carried out smoothly in a suitable organic environment, broadening its application range.
    As for the melting point, the melting point of 2% 2C3-dihydroxyacetone is about 75-80 ° C. The relatively low melting point means that it can be converted from solid to liquid under relatively mild heating conditions. This property is of great significance in material processing and some industrial processes that require precise control of physical state changes. By adjusting the temperature, its physical state can be flexibly controlled to meet the needs of different production processes.
    Its odor is weak, and there is almost no irritating odor. During use, it will not cause harm to the health of operators due to pungent odor, nor will it cause odor pollution to the surrounding environment. This characteristic makes 2% 2C3-dihydroxyacetone have broad application prospects in industries with strict odor requirements such as food and cosmetics.
    In summary, the physical properties of 2% 2C3-dihydroxyacetone, such as white crystalline powder, good solubility, low melting point and weak odor, make it show unique application value in many fields such as chemical industry, medicine, food, cosmetics, etc.
    What are the precautions for 2,3-diaminopyridine during storage and transportation?
    When storing and transporting 2% 2C3-dihydroxyacetophenone, it is necessary to pay attention to many matters.
    First, it is related to storage. This substance should be stored in a cool, dry and well-ventilated place. Because the substance is susceptible to humidity and temperature, high temperature and humidity may cause it to deteriorate, which in turn affects quality and performance. Be sure to keep away from fires and heat sources to prevent safety accidents such as fires. It needs to be stored separately from oxidants and acids, and must not be mixed. Because these substances come into contact with it or cause chemical reactions, it endangers safety. At the same time, the storage area should be equipped with suitable materials to contain leaks for emergencies.
    Second, it involves transportation. Before transportation, it is necessary to ensure that the packaging is complete and sealed. The packaging material should be able to effectively prevent the leakage and volatilization of the substance. During transportation, it is necessary to ensure that the container does not leak, collapse, fall, or be damaged. It should be strictly driven according to the specified route, and do not stop in densely populated areas and residential areas. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If a leak occurs during transportation, drivers and passengers should take immediate emergency measures to evacuate the crowd, prevent the spread of pollution, and report to relevant departments in a timely manner.
    In short, the storage and transportation of 2% 2C3-dihydroxyacetophenone should be handled with caution in terms of storage environment, packaging and transportation, etc., to ensure its quality and safety and avoid accidents.
    What are the safety risks of 2,3-diaminopyridine?
    2% 2C3 - dihydroxyacetophenone, this material has many safety risks. It is flammable, flammable in case of open flames and hot topics. In places with fire hazards, if you are not careful, if you are close to the source of fire and overheated, it is easy to cause combustion. Once the fire spreads, it will cause serious consequences.
    Furthermore, it is irritating to the eyes, skin and respiratory tract. If you contact the eyes carelessly, it can cause eye pain, redness, swelling, tears, or even damage vision; contact with the skin can cause skin redness, itching, and rash; inhalation of its dust or volatiles can cause coughing, asthma, and breathlessness, which is even more harmful to those with fragile respiratory tract.
    At the environmental level, its entry into the environment may cause pollution to water bodies, soils, etc., affect ecological balance, and interfere with the normal growth and reproduction of animals and plants. Therefore, when using and storing 2% 2C3-dihydroxyacetophenone, it is necessary to strictly follow safety procedures, take protective measures to prevent fires, avoid contact and inhalation, and properly dispose of waste to reduce safety risks and protect personal safety and environmental safety.