2 3 5 Trichloro 4 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2,3,5-trichloro-4-(trifluoromethyl)pyridine

    Specifications

    HS Code

    322643

    Chemical Formula C6HCl3F3N
    Molecular Weight 247.43
    Appearance Typically a colorless to light - yellow liquid
    Boiling Point Around 190 - 195 °C
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Vapor Pressure Low vapor pressure at room temperature
    Odor May have a pungent, chlorinated odor

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    Frequently Asked Questions

    As a leading 2,3,5-trichloro-4-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2,3,5 - trichloro - 4 - (trifluoromethyl) pyridine
    2%2C3%2C5+-+trichloro+-+4+-+%28trifluoromethyl%29pyridine is 2,3,5-trichloro-4- (trifluoromethyl) pyridine, which has a wide range of uses and has important applications in many fields such as medicine, pesticides, and materials.
    In the field of medicine, it is a key pharmaceutical intermediate. It can be converted into compounds with specific biological activities through multiple delicate reactions and used to create new drugs. For example, in the synthesis of some antibacterial and antiviral drugs, it plays a cornerstone role, providing pharmaceutical developers with an important starting material for building complex drug molecular structures and facilitating the birth of new therapies.
    In the field of pesticides, it is the core raw material for the synthesis of high-efficiency pesticides. Through chemical modification and synthesis process optimization, specific pesticides for different crop diseases and insect pests can be prepared. Due to its unique structure, pesticides can have excellent targeting and biological activity, which can not only effectively kill pests and pathogens, but also reduce the adverse impact on the environment, meeting the needs of modern agricultural green and environmental protection development.
    In the field of materials, it can be used as a synthetic building block for functional materials. After ingenious design and polymerization, its unique structure can be introduced into polymer materials, endowing the materials with characteristics such as excellent thermal stability, chemical stability and weather resistance. For example, in the synthesis of special coatings and high-performance engineering plastics, it can significantly improve material properties, broaden the application range of materials, and enable them to maintain stable performance in extreme environments.
    What are the physical properties of 2,3,5 - trichloro - 4 - (trifluoromethyl) pyridine
    2% 2C3% 2C5-trichloro-4- (trifluoromethyl) pyridine, Chinese name 2,3,5-trichloro-4- (trifluoromethyl) pyridine, is an important member of the field of organic compounds. Its physical properties are unique and it is widely used in chemical industry and scientific research.
    Looking at its properties, 2,3,5-trichloro-4- (trifluoromethyl) pyridine is often colorless to light yellow liquid at room temperature and pressure, which facilitates its uniform dispersion in many reaction systems and full contact with other reactants, thereby improving the reaction efficiency.
    Smell, has a special smell, this smell is unique and distinct, can be used as the basis for preliminary identification, however, because of its irritation, sniffing should be cautious to prevent damage to the respiratory tract.
    When it comes to boiling point, it is about 180-190 ° C. This boiling point characteristic determines its application in separation, purification and reaction condition control. Heating in a specific temperature range can achieve effective separation from other substances with large differences in boiling points.
    In terms of melting point, it is roughly around -20 ° C. The lower melting point indicates that it can still maintain a liquid state in a relatively low temperature environment, providing convenience for some chemical reactions that require low temperature operation.
    As for solubility, it is slightly soluble in water, but it can be well miscible with most organic solvents such as ethanol, ether, acetone, etc. This solubility characteristic makes it possible to flexibly select suitable organic solvents according to the reaction requirements in organic synthesis, build a homogeneous reaction system, and promote the smooth progress of the reaction.
    The density is about 1.6-1.7 g/cm ³, which is relatively large. When it involves delamination, extraction, etc., the density characteristic can help to judge its distribution position in the mixed system, providing an important reference for experimental operation. The physical properties of 2,3,5-trichloro-4- (trifluoromethyl) pyridine, such as properties, odor, melting point, solubility, and density, are interrelated and play their respective roles. They are of great significance in many fields such as organic synthesis and materials science, laying a solid foundation for related research and production practices.
    What are the chemical properties of 2,3,5 - trichloro - 4 - (trifluoromethyl) pyridine
    2%2C3%2C5+-+trichloro+-+4+-+%28trifluoromethyl%29pyridine, that is, 2,3,5 -trichloro-4- (trifluoromethyl) pyridine, this is an organic compound. Its chemical properties are unique and of great significance in the field of organic synthesis.
    First, the presence of chlorine atoms and trifluoromethyl in this compound significantly affects its chemical activity. Chlorine atoms have certain electronegativity, which can reduce the electron cloud density of the pyridine ring, making the pyridine ring more prone to electrophilic substitution, and the substitution check point is affected by the positioning effect of chlorine atoms and trifluoromethyl. Trifluoromethyl is a strong electron-absorbing group, which further enhances the electrophilic substitution activity of the pyridine ring, and often guides the electrophilic reagent to attack the specific position of the pyridine ring.
    Secondly, the chlorine atoms in 2,3,5-trichloro-4- (trifluoromethyl) pyridine can participate in nucleophilic substitution reactions. Under suitable nucleophilic reagents and reaction conditions, chlorine atoms can be replaced by nucleophilic reagents to form new organic compounds, providing the possibility for the construction of diverse organic molecular structures.
    Furthermore, the compound has good thermal and chemical stability due to its trifluoromethyl content. The high carbon-fluorine bond energy in trifluoromethyl improves the overall stability of the molecule. Under high temperature or strong chemical reagent environment, it is more difficult to decompose or chemically react than ordinary organic compounds.
    In addition, the physical properties of 2,3,5-trichloro-4- (trifluoromethyl) pyridine are also affected by its structure. Due to the existence of chlorine atoms and trifluoromethyl, the molecular polarity changes, which affects its solubility in different solvents. In some organic solvents, it may exhibit specific solubility characteristics, which provides convenience for its operation in organic synthesis and separation and purification.
    2,3,5-trichloro-4- (trifluoromethyl) pyridine has rich and diverse chemical properties and may have wide application prospects in organic synthesis, materials science and other fields. Through in-depth research and rational utilization of its chemical properties, many organic compounds with special properties can be prepared.
    What are the synthesis methods of 2,3,5 - trichloro - 4 - (trifluoromethyl) pyridine
    The synthesis of 2% 2C3% 2C5-trichloro-4- (trifluoromethyl) pyridine is an important topic in the field of organic synthesis. There are several common methods for its synthesis.
    First, the compound containing the pyridine structure is used as the starting material. Appropriate pyridine derivatives can be taken first, and chlorine atoms can be introduced through halogenation. In this process, appropriate halogenation reagents, such as phosphorus oxychloride, need to be selected. Halogenation reaction conditions are very critical, and the temperature, reaction time and proportion of reactants need to be precisely regulated. After the chlorine atoms are successfully introduced into the specific position of the pyridine ring, trifluoromethyl is introduced. The method of introducing trifluoromethyl can be used by trifluoromethylation reagents, such as trifluoromethyl halide, etc. Under the action of appropriate catalysts, trifluoromethyl can be connected to achieve the access of trifluoromethyl, and then the target product can be obtained 2% 2C3% 2C5 -trichloro-4- (trifluoromethyl) pyridine.
    Second, other simple compounds can also be used as the starting point to construct pyridine rings through multi-step reactions. First, the pyridine parent nucleus is formed from simple organic raw materials through condensation, cyclization and other reactions. This step requires selecting suitable reaction conditions and catalysts according to the reaction mechanism to promote the reaction to generate pyridine rings. After the pyridine ring is formed, the chlorination and trifluoromethylation reactions are carried When chlorinating, pay attention to control the selectivity of the reaction and ensure that the chlorine atom is substituted at the specified position. When trifluoromethylation, the reaction efficiency and product purity should also be considered.
    Third, the synthesis path of transition metal catalysis can also be used. The unique activity and selectivity of transition metal catalysts are used to make the reactants react under mild conditions. For example, transition metals such as palladium and copper are used as catalysts with specific ligands to achieve the precise introduction of chlorine atoms and trifluoromethyl. This method requires high requirements for the reaction system, and the reaction environment needs to be strictly controlled to improve the yield and selectivity of the reaction. Finally, 2% 2C3% 2C5 -trichloro-4- (trifluoromethyl) pyridine was successfully synthesized.
    What is the price range of 2,3,5 - trichloro - 4 - (trifluoromethyl) pyridine in the market?
    I think what you are asking is about the price range of "2,3,5-trichloro-4- (trifluoromethyl) pyridine" in the market. However, the price of this product is difficult to determine, because the market situation changes and many factors interact.
    First, the trend of supply and demand has a lot to do with it. If there are many people who want this product, and there are few people who supply it, the price will rise; on the contrary, if the supply exceeds the demand, the price may fall. Second, the production cost is also the key. The price of raw materials, the method of production, and the consumption of manpower and material resources all affect the cost, which in turn affects the price. Third, the state of market competition cannot be ignored. Compete with the industry, or reduce prices to attract customers, or increase prices due to exclusive advantages.
    With common sense, this chemical may have applications in fine chemicals and other fields. However, due to the lack of detailed market surveys, it is difficult to accurately inform its price range. For details, you can consult chemical product trading platforms, industry experts, or professional market reports to get a relatively accurate number.