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What are the main uses of 2- (2-pyridylthio) pyridine?
Among the many process materials involved in "Tiangong Kaiwu", 2- (2-mica-based aggregate) mica is mainly used for a wide range of purposes.
Mica, with its flexible nature and unique luster, has important functions in many fields in ancient times. In the art of papermaking, mica powder can be added to pulp. In this way, the surface of the produced paper is smoother and has a unique luster. When writing, the ink is evenly stained, and it can also prevent moths, greatly improving the quality of the paper and prolonging the storage time.
In the field of painting pigment production, mica is also a key raw material. After fine grinding and processing, it can be made into pigments with gorgeous and long-lasting color. Pigments based on mica, painted on silk or paper, flash a unique light under the light, making the painting more layered, showing extraordinary visual effects, making the painting still shine through the years.
In ancient architectural decoration, mica also plays an important role. Mica sheets are inlaid on doors, windows and screens. During the day, when sunlight penetrates, mica refracts light, making the interior light and shadow mottled, creating a wonderful atmosphere; at night, candlelight reflects, adding a sense of warmth and fantasy, greatly enhancing the aesthetic and artistic atmosphere of architectural decoration.
In addition, in alchemy and other alchemy activities, mica is often regarded as an important raw material. The alchemists believed that mica contained special "spiritual energy", which could be refined to prolong life through specific refining methods. Although this understanding was biased from the perspective of modern science, mica occupied a certain position in the development of ancient alchemy.
What are the physical properties of 2- (2-pyridylthio) pyridine?
2 - (2 - to the base of its artillery) to its material rationality, this is related to the wonders created by the immortals. The base of its artillery is made of a combination of mysterious materials and mysterious methods, with wonderful properties.
Its physical rationality is the first and most common, such as the essence of the machine, and the essence of the machine. It is a sharp-edged chopping, and it is a fierce beating, all of which leave a trace mark on its surface. The attack of the magic method like the face can also be resisted, and the ability to prevent the machine is excellent.
Furthermore, this object has the best performance characteristics. The general power, mana and even the special energy of heaven and earth can be attracted. Such as the diversion of water in a river, the energy generation follows a specific process, and in the process of energy generation, it is difficult to consume energy. This feature makes it an important part in the work of magic tools, which can greatly improve the efficiency of magic tools.
In addition, its efficiency is very common. It seems to be thick and heavy, but when you hold it in your hand, it feels like a hair. This feature allows the user to control the magic tool or perform the magic method of the phase, which is more convenient, not burdened by weight, and can make exquisite work in an instant, which is the first to be used in magic or magic.
Therefore, 2 - (2 - to its base gun base) to its things, with their physical properties such as performance, performance, and profitability, occupy an important position in the immortal family, and provide an indispensable help for the operation of multi-method magic tools.
What are the chemical properties of 2- (2-pyridylthio) pyridine?
2-%282-%E5%90%A1%E5%95%B6%E5%9F%BA%E7%A1%AB%E5%9F%BA%29 is 2- (2 -hydroxybenzoic acid), that is, hydroxybenzoic acid, commonly known as salicylic acid. The following describes its chemical properties in the classical Chinese form of "Tiangong Kaiwu":
Fujiybenzoic acid, with unique and wonderful properties. It is at room temperature, in the shape of white crystals, quietly alone, if hidden in the world of Guru. Smell it, there is little odor, just like a humble gentleman, restrained but not flamboyant.
When heated, it gradually melts, turning the visible into the invisible state, such as ice disappearing under the warm sun, supple and changing. It is slightly soluble in water, and it seems to be in a state of being detached from water. It is not in a hurry to blend, nor does it reject it decisively. It is like the fate of the world, and it exists delicately.
However, it is in organic solvents such as alcohols and ethers, but it can readily dissolve, just like a bosom friend meeting, and it is intimate. This is because of the structure of its molecules, which is in harmony with organic solvents, in order to be able to blend so well.
Hydroxybenzoic acid is acidic and can be combined with alkali phases, such as yin and yang sympathetic, and new substances can be transformed. When reacting with alkali, it is like a silent dance, and the molecules interact with each other, rearranging the structure, and generating corresponding salts. In water, the solubility of this salt is better than that of hydroxybenzoic acid itself, and it is like a rebirth and can be reborn.
And because there are hydroxyl groups in its structure, it has the properties of phenols. It can meet the ferric chloride test solution and instantly change the color of corydalis. This change is very magnificent, like the flower of the dark night blooming instantly, which is its unique logo, which is different from other things. This reaction is sensitive and specific. It is a wonderful way to identify hydroxybenzoic acid and has contributed to the field of chemical identification.
What are the synthesis methods of 2- (2-pyridylthio) pyridine?
To prepare 2 - (2 - alkynyl borate) alkynyl compounds, there are many synthesis methods, each with its own advantages and disadvantages. The following are common methods:
###Cross-coupling reaction method
1. ** Sonogashira coupling reaction **: This is a classic method, using palladium (Pd) and copper (Cu) as catalysts, halogenated aromatics or halogenated alkenes react with terminal alkynes under basic conditions. For example, using halogenated 2 - (2 - borate ester) aromatics and terminal alkynes as raw materials, under the catalysis of tetra (triphenylphosphine) palladium (0) and cuprous iodide, potassium carbonate as a base, in N, N - dimethylformamide (DMF) solvent, heating and stirring, the target product can be obtained. This reaction condition is mild, the substrate is widely adaptable, but the catalyst cost is higher, and the post-treatment is slightly more complex.
2. ** Negishi coupling reaction **: The reaction of organozinc reagent with halogenated hydrocarbons or sulfonates is catalyzed by palladium or nickel. When preparing 2 - (2 - alkynyl borate) alkynyl compounds, an organozinc reagent containing borate groups can be prepared first, and then coupled with halogenated alkynes. The reaction has good selectivity and can construct complex carbon-carbon bonds. However, the organozinc reagent is sensitive to water oxygen, and the preparation and operation require an anhydrous and oxygen-free environment.
###alkynylation reaction method
1. ** Reaction of alkynyl halides with borate esters **: alkynyl halides such as alkynyl bromide or alkynyl chloride react with 2 - borate ester compounds in the presence of basic and suitable ligands. For example, cesium carbonate is used as a base and 1,10-phenanthroline is used as a ligand, and the two react in toluene solvent. This method is easy to obtain raw materials, relatively simple to operate, but the reactivity is sometimes poor, and the conditions need to be optimized.
2. ** Alkynyl lithium or alkynyl Grignard reagent method **: The alkynyl lithium or alkynyl Grignard reagent is first prepared, and then reacts with the carbonyl compound containing the borate ester group, and the target product is obtained by hydrolysis and other steps. For example, the reaction of alkynyl lithium with 2-borate ester aldehyde, and then acidification and hydrolysis. This method has high reactivity, but the preparation of alkynyl lithium and alkynyl Grignard reagent requires harsh conditions such as low temperature, and is sensitive to water
What is the price range of 2- (2-pyridylthio) pyridine in the market?
There is a question today: What is the price range of two minus (two minus its bases) in the market? When answering in the classical style of "Tiangong Kaiwu".
If you want to know what something is in the market price range, you need to consider all the reasons in detail. However, just say "two minus (two minus its bases) ", this phrase is brief, and it is not clear what the "base" refers to is, nor does it involve many veins related to the market price, such as origin, season, supply and demand, quality, etc.
If you want to clarify the price range in a common sense, the cost will be different if the origin is different, and the price will also be different. For example, what is produced in mountains and seas, sold in different places, and freight will all affect the price. The change of seasons is also related to the price. For things that are in time, the price may be easy; for products that are not in time, the price may be high. In the state of supply and demand, if the supply exceeds the demand, the price will drop; if the supply exceeds the demand, the price will rise. Quality is good or bad, the price of the better is high, and the price of the inferior is low.
It is difficult to confirm that it is within the market price range. To obtain an accurate number, it is still necessary to make up for the details, so as to deduce the approximate price range.