2 2 Phenylethyl Sulfanyl Pyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2-[(2-phenylethyl)sulfanyl]pyridine-3-carboxylic acid

    Specifications

    HS Code

    796981

    Chemical Formula C14H13NO2S
    Molecular Weight 259.32
    Physical State Solid (assumed from common nature of similar organic acids)
    Solubility In Water Low solubility expected (due to non - polar phenyl and sulfur - containing groups)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane (typical for aromatic organic acids)

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 2- [ (2-phenethyl) thio] pyridine-3-carboxylic acid?
    2-%5B%282-%E8%8B%AF%E4%B9%99%E5%9F%BA%29%E7%A1%AB%E5%9F%BA%5D%E5%90%A1%E5%95%B6-3-%E7%BE%A7%E9%85%B8%E7%9A%84%E5%8C%96%E5%AD%A6%E7%BB%93%E6%9E%84%E4%B8%93%E6%A0%87%E4%B9%8E%E7%94%B1%E6%9C%89%E6%9C%89%E7%BE%A7%E9%85%B8%E7%9A%84%E7%9F%A5%E8%AF%86%E8%80%8C%E5%AE%9A. However, in order to clarify the details, it is necessary to know the principles of organic chemistry.
    In this compound, 2 - [ (2 - benzyl) carbonyl] pentyl-3 - heptanoic acid, where "2 - [ (2 - benzyl) carbonyl] pentyl" is the substituent, and "3 - heptanoic acid" is the main part. For heptanoic acid, the carboxylic group of the main chain containing seven carbons is located at one end of the main chain. At position 3, there are "2 - [ (2 - benzyl) carbonyl] pentyl" substituents connected.
    Benzyl, benzyl also, its structure is benzene ring-linked methylene. Carbonyl is a carbon-oxygen double bond structure (C = O). "2-benzyl" is connected to the carbon of the carbonyl group, which in turn is connected to the amyl group. The amyl group is an alkyl chain containing five carbons. The end of this amyl group connected to the carbonyl group is connected to the 3-position carbon of the main chain of heptanoic acid.
    In summary, the chemical structure of 2- [ (2-benzyl) carbonyl] pentyl-3-heptanoic acid is composed of the main chain of heptanoic acid, which is connected to complex substituents containing benzyl, carbonyl and pentyl at the third position. This structure is used in the field of organic chemistry, or involves the study of reaction mechanism, synthesis path, etc. Due to the characteristics of different functional groups, the compound has unique chemical properties.
    What are the main physical properties of 2- [ (2-phenethyl) thio] pyridine-3-carboxylic acids?
    2-%5B%282-%E8%8B%AF%E4%B9%99%E5%9F%BA%29%E7%A1%AB%E5%9F%BA%5D%E5%90%A1%E5%95%B6, this is a chemically related expression, which involves the " (2-benzyl) carbonyl" group-related reactions and other contents. 3-carboxylic acids have many important physical properties, which are described in classical Chinese as follows:
    Carboxylic acids have unique properties. Its melting boiling point is often higher than that of hydrocarbons and ethers of the same carbon number. Gein carboxylic acids can form hydrogen bonds between molecules, and the interaction is quite strong. Take formic acid and acetic acid as an example, they are liquid at room temperature, while carboxylic acids of low carbon number can be miscible with water, and their carboxyl groups can form hydrogen bonds with water molecules, so they can be miscible. However, with the growth of the carbon chain, its solubility in water gradually decreases, to high-grade fatty acids, almost insoluble in water, but easily soluble in organic solvents, such as ethanol, ether, etc. This is due to the growth of the carbon chain, the non-polar part increases, and it is similar to the non-polar of organic solvents, following the principle of "similar miscibility".
    Furthermore, carboxylic acids are acidic and can ionize hydrogen ions in water. However, their acidity is weaker than that of inorganic strong acids, and can neutralize with bases to form carboxylic salts and water. For example, acetic acid reacts with sodium hydroxide to obtain sodium acetate and water. And carboxylic acids of different structures also have different acidity, which is related to the groups connected to the carboxyl group. If the electron-withdrawing group is connected, the density of the carboxyl group electron cloud can be reduced, and hydrogen ions can be ionized more easily, and the acidity can be enhanced; if the electron-withdrawing group is connected, the acidity will be weakened.
    The physical properties of carboxylic acids are of great significance in chemical research, industrial production and daily life. In organic synthesis, the use of its solubility, acidity and other properties can realize the separation, purification and transformation of substances, which is also the basis of many chemical reactions.
    In what fields are 2- [ (2-phenethyl) thio] pyridine-3-carboxylic acids used?
    The content of 2 - [ (2 - benzyl) carbonyl] to its 3 - carboxylic acid seems to be chemically related, but the expression is slightly confusing, speculating or discussing the structure and related properties of a chemical substance. Today, according to the classical Chinese format of "Tiangong Kaiwu", try to answer this question.
    Fu 2 - [ (2 - benzyl) carbonyl] -3 - carboxylic acids are useful in the fields of chemical industry and medicine. In the field of chemical industry, it can be used as a raw material for organic synthesis. With its structural characteristics, it can react with various reagents to obtain a variety of organic compounds, which may be beneficial for the preparation of dyes and fragrances.
    As for the medical environment, it may have potential pharmacological activity. Because of its specific chemical structure, it may be combined with biological targets to regulate physiological processes. Or it can be used to develop new drugs to treat various diseases.
    However, its application also needs to be considered in detail. In the process of synthesis, attention must be paid to the control of reaction conditions, such as temperature, pH, etc., to ensure the purity and yield of the product. In medical applications, it is even more necessary to carefully evaluate its safety and effectiveness, and undergo rigorous experimental and clinical verification before it can be put into practical use.
    Although this substance has the potential for application, if you want to make the best use of it, you must use scientific methods to explore in detail and weigh the advantages and disadvantages in order to achieve the purpose of good use.
    What are the synthesis methods of 2- [ (2-phenethyl) thio] pyridine-3-carboxylic acids?
    To prepare 2 - [ (2 - benzyl) carboxyl] to its - 3 - carboxylic acid, the following synthesis methods can be used:
    First, a halogenated hydrocarbon is reacted with a carboxylic acid derivative. Select an appropriate halogenated benzyl to perform a nucleophilic substitution reaction with diethyl malonate and alkaline reagents such as sodium alcohol. The halogen of halogenated benzyl is attacked by the active methylene carbon negative ion in diethyl malonate to form a new carbon-carbon bond. Then, the product is hydrolyzed and decarboxylated to obtain the target carboxylic acid. In this process, the amount of basic reagents, reaction temperature and time need to be precisely controlled. If the alkalinity is too strong, the reaction temperature is too high or the time is too long, the side reaction may occur, and the yield will be reduced.
    Second, the Grignard reagent method is used. First, benzyl Grignard reagent is prepared by halogenated benzyl, which is reacted with carbon dioxide at low temperature to form carboxylate, and then acidified to obtain the target carboxylic acid. In this path, the preparation of Grignard reagent requires an anhydrous and oxygen-free environment, otherwise it is easy to cause the reaction to fail. The entry rate of carbon dioxide is also particular. Too fast or too slow may affect the reaction process and yield.
    Third, it is based on the Fu-Ke acylation reaction of aromatic rings. First, benzyl benzene is acylated by Fu-Ke, an acyl group is introduced, and then the acyl group is oxidized to a carboxyl group. In the Fu-Ke acylation reaction, factors such as the choice and amount of catalyst, the reaction solvent and other factors have a great influence on the reaction area selectivity and yield. When oxidizing acyl groups, it is necessary to choose the appropriate oxidant and reaction conditions according to the specific situation to achieve an efficient and highly selective oxidation effect.
    All this synthesis method has its own advantages and disadvantages. In fact, it is necessary to comprehensively weigh and weigh various factors such as the availability of raw materials, the difficulty of reaction conditions, cost and yield, and make a careful choice to achieve the ideal synthesis effect.
    What are the market prospects for 2- [ (2-phenethyl) thio] pyridine-3-carboxylic acids?
    The market prospect of 2 - [ (2 - benzyl) carbonyl] to its - 3 - carboxyl group is indeed an important matter worth exploring.
    As far as 2 - [ (2 - benzyl) carbonyl] to its - 3 - carboxyl group is concerned, it has a wide range of uses in today's chemical industry. This compound can be used as a key intermediate in the field of pharmaceutical synthesis. The preparation of many drugs depends on its unique chemical structure to achieve specific pharmacological activities. For example, some drugs with antibacterial and anti-inflammatory effects play an indispensable role in the synthesis of 2- [ (2-benzyl) carbonyl] to its -3-carboxyl group.
    From the perspective of market demand, with the growth of the global population and the increase in people's attention to health, the pharmaceutical industry continues to thrive. The demand for such compounds for drug synthesis is also rising. And in the field of materials science, it may be used to prepare special polymer materials, endowing materials with unique properties such as good stability and plasticity. With the progress of high-end manufacturing, the demand for special materials is also increasing, which indirectly promotes the market demand for 2-[ (2-benzyl) carbonyl] to its -3-carboxyl group.
    Furthermore, from the supply level analysis, although there are currently a certain number of production enterprises, due to certain difficulties in the synthesis process, some technologies still need to be perfected, resulting in production capacity that cannot fully meet the potential demand of the market. This is also the driving force for many enterprises to develop better synthesis processes.
    To sum up, the market prospects for 2- [ (2-benzyl) carbonyl] to its -3-carboxyl group are quite bright. Driven by strong demand in the fields of medicine and materials, if synthesis technology can further break through, increase production capacity and reduce costs, its market scale is expected to continue to expand, and it will occupy a more important position in the chemical industry stage.