2-(2-Nitrophenyl)imidazo[1,2-A]pyridine

2- (2-aminopyridine) amide [1,2-A] pyridine is mainly used in many important fields. In the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of drug molecules with specific biological activities. Due to its unique chemical structure and electronic properties, it can interact with specific targets in organisms. For example, some compounds with such structures have inhibitory effects on the growth of certain cancer cells, or can regulate neurotransmitter transmission, laying the foundation for the development of anti-cancer drugs and drugs for the treatment of nervous system diseases.
In the field of materials science, it can participate in the preparation of functional materials. By virtue of its own structure, specific functional groups can be introduced, giving materials special properties. If used in the preparation of photoelectric materials, it can affect the properties of materials such as light absorption and charge transport, and has potential applications in organic Light Emitting Diode (OLED), solar cells and other fields.
In the field of organic synthetic chemistry, it is an important synthetic building block. Its structure can be modified and expanded by a variety of chemical reactions to construct complex organic molecular structures. Chemists can use it to react with different reagents to synthesize organic compounds with diverse structures and different functions, greatly enriching the library of organic compounds, providing many possibilities for the development of new drugs and the creation of new materials. In conclusion, 2 - (2-aminopyridine) amide [1,2-A] pyridine, with its unique structure and properties, plays an important role in many fields such as medicine, materials, and organic synthesis, and has broad application prospects and research value.

To obtain 2 - (2 - purinyl) pyridino [1,2 - A] pyrimidine synthesis methods can be considered in ancient methods, and there are three ways.
First, the nitrogen-containing heterocyclic ring is the beginning, and it is formed by condensation reaction. First, take the appropriate pyridine derivatives and purinyl-related intermediates, and condensate the two under a specific acid-base environment and temperature. Among them, the degree of acid and base and the control of temperature are the key. If the acid-base is unbalanced, the reaction will be stagnant or chaotic; if the temperature is improper, the purity and yield of the product will be disturbed. It is necessary to observe the reaction process carefully and adjust the conditions in a timely manner to make the two condense smoothly and obtain the required ring structure. < Br >
Second, with the help of transition metal catalysis. Select suitable transition metal catalysts, such as palladium, copper, etc., with specific ligands. With halogenated pyridine and purinyl halide as raw materials, under the action of the catalyst, a coupling reaction occurs. In this process, the activity of the metal catalyst and the structure of the ligand have a great impact on the reaction. If the activity is too high or too low, the reaction or too fast will cause side reactions, or too slow and inefficient. The coordination mode between ligands and metals is also related to the selectivity and rate of the reaction. Careful screening of combinations is required to make the reaction efficient and directional.
Third, the strategy of intramolecular cyclization is adopted. First, a precursor is constructed to contain cyclized structural fragments, such as alkenyl, alkynyl, and nitrogen-containing groups. Under appropriate reaction conditions, intracyclization reactions are initiated. Among them, the cyclization conditions, such as lighting, heating, or the addition of specific reagents, need to be precisely controlled. The intensity of light, the temperature of heating, and the amount of reagents are slightly different, and the check point of cyclization and the configuration of the product may be different. Therefore, careful consideration is required to achieve the expected cyclic product.

The physical and chemical properties of 2 - (2-aminopyridine) amide and [1,2-A] pyridine are particularly important and are fundamental to many chemical applications.
Its physical properties, appearance is often in a specific form, either crystalline or powdery, depending on the synthesis conditions and purity. Melting point is also a key physical parameter. Different preparation methods or melting points vary slightly, but they are generally in a certain temperature range. This can be accurately measured by a melting point tester, providing an important basis for the identification of the substance. In terms of solubility, in common organic solvents such as ethanol and dichloromethane, it exhibits specific solubility characteristics. In polar solvents, it may have certain solubility, while in non-polar solvents, the solubility may be low. This characteristic is closely related to the polar structure of the molecule, which has a profound impact on its reaction and separation operations in solution.
As for chemical properties, the molecular structure of 2 - (2-aminopyridine) amide and [1,2 - A] pyridine contains multiple activity check points. The amino moiety is alkaline and can neutralize with acids to form corresponding salts. This property can be used to adjust the pH of the reaction system in organic synthesis, which in turn affects the process and direction of the reaction. The structure of the pyridine ring and the amide also endows it with unique reactivity. The carbon atoms on the pyridine ring can participate in the electrophilic substitution reaction, and the amide bond can undergo hydrolysis, condensation and other reactions under specific conditions. These reactivity makes the compound show broad application prospects in the fields of medicinal chemistry and materials science, and can be used as a key intermediate to participate in the construction of complex organic molecules, laying the foundation for the creation of new drugs and functional materials.

I look at your question, but I am inquiring about the price range of (2- (2-carboxylbenzyl) pyridino [1,2-A] pyrimidine in the market. This is a fine chemical or pharmaceutical intermediate, and its price varies according to quality, quantity, supply and demand, and market conditions.
If it is of high quality, well-prepared, free of impurities and pure, the price may be high. In small-scale experimental dosage, in milligrams, each milligram may reach several gold to tens of gold. Due to the use of research and development, the quality is demanding, and it is difficult to make, so the cost is high.
If it is mass-produced in industrial grade, in kilograms, the unit price may drop due to the scale effect. However, it also depends on whether the production process is complicated or not and the cheapness of the raw materials. If the process is simple, the raw materials are easy to obtain and cheap, or hundreds of gold per kilogram; if the process is complex and the raw materials are rare, or thousands of gold per kilogram.
The supply and demand of the city are also heavy. If there are many applicants, the price will rise if there are few suppliers; if the supply exceeds the demand, the price may be depressed. And different regions have different prices. In economically developed places, the price may be slightly higher due to high operating costs; in remote places, it may be slightly lower.
In conclusion, the market price of (2 - (2 - carboxylbenzyl) pyridino [1,2 - A] pyrimidine varies from a few gold per milligram to several thousand gold per kilogram. It is difficult to determine the exact price, depending on the circumstances.

You are inquiring about the storage conditions of (2 - (2 - aminopyridine) boric acid [1,2 - A]. This (2 - (2 - aminopyridine) boric acid [1,2 - A]) is a chemical substance, and its storage needs to be treated with caution to ensure its stability and avoid the risk of danger.
First, it should be placed in a cool place. High temperature can easily cause it to undergo chemical reactions, or decompose and deteriorate, which will damage its chemical activity. The temperature in the cool place is relatively stable, which can slow down its chemical change rate and maintain its original properties.
Second, a dry environment is indispensable. Because it has certain chemical activity, it can change its chemical structure and properties in contact with water vapor or moisture absorption and hydrolysis. Therefore, it should be stored in a dry place, or accompanied by a desiccant, in addition to ambient water vapor.
Third, it needs to be sealed and stored. Open to the air, or react with gases such as oxygen and carbon dioxide. Sealing can block the intrusion of external gases and maintain its chemical purity.
Fourth, keep away from fire sources and strong oxidants. This chemical substance may be flammable or react violently with strong oxidants, causing fire, explosion and other hazards. Therefore, the storage place should be protected from fire sources and strong oxidants.
In summary, (2 - (2 - aminopyridine) boric acid [1,2 - A]) should be stored in a cool, dry place, sealed, and far from the fire source and strong oxidant, so as to ensure its quality and safety.