2 2 Methylaminoethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-(2-Methylaminoethyl)Pyridine

    Specifications

    HS Code

    327504

    Chemical Formula C8H12N2
    Molecular Weight 136.194 g/mol
    Appearance Typically a liquid
    Boiling Point Around 222 - 224 °C
    Solubility Soluble in organic solvents like ethanol, chloroform
    Vapor Pressure Low at room temperature
    Odor May have a characteristic amine - like odor

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    General Information
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    Frequently Asked Questions

    As a leading 2-(2-Methylaminoethyl)Pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (2-Methylaminoethyl) Pyridine?
    2-% 282 - Methylaminoethyl%29Pyridine is 2 - (2 - methylaminoethyl) pyridine, which has a wide range of uses. In the field of medicine, it is an important intermediate in organic synthesis and can be used to create many drugs. For example, in the synthesis path of some cardiovascular drugs, with its unique chemical structure, it participates in key reaction steps, which is of great significance for the construction of drug active structures, and helps to improve the therapeutic effect of drugs against cardiovascular diseases.
    In the field of materials science, it also plays an important role. It can be used as a synthetic raw material for special functional materials, which can be combined with other compounds through specific reactions to give novel properties to the materials. For example, the preparation of some polymer materials with special electrical conductivity or optical properties, 2 - (2 - methylaminoethyl) pyridine is involved, which can optimize the internal structure of the material and make the material exhibit excellent performance in electronic devices, optical display and other fields.
    In the field of organic synthetic chemistry, as a nitrogen-containing heterocyclic compound, its chemical activity is high, and it can participate in a variety of organic reactions, such as nucleophilic substitution and addition reactions. With the synergy effect of pyridine ring and methylaminoethyl, it provides an effective way for the synthesis of complex organic compounds, expands the diversity of organic synthesis, and promotes the development and progress of organic synthetic chemistry.
    What are the synthesis methods of 2- (2-Methylaminoethyl) Pyridine
    2 -% 282 - Methylaminoethyl%29Pyridine is 2 - (2 - methylaminoethyl) pyridine. The common synthesis methods are as follows:
    First, 2 - pyridyl acetonitrile is used as the starting material. First, 2 - (2 - methylaminoethyl) pyridyl nitrile is synthesized by adding 2 - pyridyl acetonitrile with monomethylamine in a suitable solvent at a certain temperature and pressure under a specific catalyst. Subsequently, the product is reduced under hydrogenation reduction conditions, such as Raney nickel as a catalyst, and hydrogen is introduced to reduce the nitrile group to an amino group, thereby preparing 2 - (2 - methylaminoethyl) pyridine. The starting materials of this route are relatively easy to obtain. Although the reaction steps are relatively clear, the hydrogenation reduction step needs to be controlled by reaction conditions to ensure the purity and yield of the product.
    Second, 2-chloropyridine and 2-methylaminoethanol are used as raw materials. Under basic conditions, the chlorine atoms in 2-chloropyridine are active and undergo nucleophilic substitution with 2-methylaminoethanol. Potassium carbonate can be used as a base, and the reaction is carried out in an appropriate organic solvent such as N, N-dimethylformamide (DMF). The reaction process requires strict control of temperature and reaction time to prevent side reactions from occurring. After nucleophilic substitution, the target product 2 - (2-methylaminoethyl) pyridine can be obtained. The method has common raw materials and relatively convenient reaction operation, but attention should be paid to the selectivity and conversion of nucleophilic substitution reaction.
    Third, pyridine and 2-methylaminoethanol are used as the starting materials. Under specific catalyst and heating conditions, pyridine and 2-methylaminoethanol can undergo condensation reaction to form the target product. This reaction requires screening of high-efficiency catalysts to improve the reaction activity and selectivity. At the same time, the reaction temperature and time also have a great influence on the yield and purity of the product, which needs to be carefully regulated.
    The above methods have their own advantages and disadvantages. In actual synthesis, factors such as raw material cost, reaction conditions, product purity and yield need to be comprehensively considered, and the most suitable synthesis path should be selected.
    What are the physical properties of 2- (2-Methylaminoethyl) Pyridine?
    2 - (2 - methylaminoethyl) pyridine is a kind of organic compound. Its physical properties are unique, and it is mostly liquid under normal temperature and pressure. Looking at its color, it is usually colorless and transparent, just like a clear spring, pure and free of variegated colors. Its smell also has characteristics, with a special smell, this smell is quite significant, which can leave a deep olfactory impression.
    When it comes to solubility, this substance can be soluble in many organic solvents, such as ethanol and ether. In ethanol, it is like fish entering water, and it can blend with it to show good solubility. This property makes it widely used in many fields such as organic synthesis. Because it can be used as an excellent solvent to help the smooth progress of chemical reactions.
    In addition, its boiling point is also considerable, and the boiling point value is specific. This property makes it possible to achieve the purpose by distillation and other methods in the process of separation and purification according to the difference in boiling points. Its boiling point characteristics ensure that under specific temperature conditions, it can be effectively separated from the mixture, just like panning gold in sand, and pure 2- (2-methylaminoethyl) pyridine can be accurately obtained.
    In terms of density, there is also a fixed value. This density characteristic is of great significance in practical operation and application. For example, when storing and transporting, understanding its density can better plan the capacity and load-bearing mode of the container, and ensure the safety and efficiency of material storage and transportation. It is like marching in formation, and all links need to be carefully arranged.
    What are the precautions for 2- (2-Methylaminoethyl) Pyridine during storage and transportation?
    For 2 - (2 -methylaminoethyl) pyridine, many matters should be paid attention to during storage and transportation. This substance has certain chemical activity. When storing, the temperature and humidity of the environment should be the first priority. It should be placed in a cool, dry and well-ventilated place. If the temperature and humidity are too high, or its properties may change, which will affect the quality. And it should be kept away from fire and heat sources. Because it is flammable, there is a risk of combustion and explosion in case of open flames and hot topics.
    Furthermore, storage should be separated from oxidants and acids to avoid mixed storage to prevent violent chemical reactions. The packaging must be tightly sealed to prevent it from evaporating or reacting with air components.
    When transporting, make sure that the container does not leak, collapse, fall or damage. The transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. During driving, it should be protected from exposure to the sun, rain and high temperature. When transporting by road, drive according to the specified route and do not stop in residential areas and densely populated areas. The loading and unloading process also needs to be handled with caution, light loading and unloading to prevent damage to packaging and containers. In this way, the safety of 2 - (2 - methylaminoethyl) pyridine during storage and transportation will not cause danger or poor quality.
    What are the effects of 2- (2-Methylaminoethyl) Pyridine on the environment and human health?
    2-% 282 - Methylaminoethyl%29Pyridine is 2 - (2 - methylaminoethyl) pyridine. The impact of this substance on the environment and human health cannot be ignored.
    At the environmental end, if it enters the water body, it may cause the water quality to deteriorate. Because of its chemical properties, it may interfere with the normal metabolism and reproduction of aquatic organisms. Microorganisms in the water may be inhibited by it, causing ecological imbalance, such as algae growth or being affected, and then affecting the entire aquatic food chain. If released in the soil, or changing the chemical properties of the soil, it will affect the absorption of nutrients by plant roots, hinder plant growth, reduce vegetation coverage, and affect regional ecological stability. And it may be difficult to degrade in the environment, and long-term residue accumulation, which is more harmful.
    As for human health, inhalation through the respiratory tract can irritate the mucosa of the respiratory tract, causing cough, asthma and other discomfort, and even damage lung function. If it is exposed to the skin, or causes skin allergies, itching, redness and swelling. Accidental ingestion may hurt the stomach, cause vomiting, abdominal pain, etc. Long-term exposure to this environment may have a potential carcinogenic risk, affect the physiological functions of normal human cells, interfere with gene expression, cause abnormal cell proliferation, and endanger life and health. It should be treated with caution, take good protection and control, and do not allow the harm to spread.