2 2 Dimethylaminoethyl P Methoxybenzyl Amino Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-[(2-dimethylaminoethyl)(p-methoxybenzyl)amino]-pyridine

    Specifications

    HS Code

    435668

    Chemical Formula C20H27N3O
    Molecular Weight 325.45 g/mol
    Appearance Typically a solid (physical state can depend on purity and conditions)
    Melting Point No widely - reported standard value (requires experimental determination)
    Solubility Solubility in organic solvents like dichloromethane, chloroform; limited solubility in water
    Pka The pKa of the pyridine nitrogen and the dimethylamino group would be relevant, but no standard value given without experiment
    Flash Point No commonly - known value without experimental determination
    Density No standard reported density value without experimental measurement
    Stability Stable under normal conditions, but can react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2-[(2-dimethylaminoethyl)(p-methoxybenzyl)amino]-pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2- [ (2-dimethylaminoethyl) (p-methoxybenzyl) amino] pyridine?
    2 - [ (2-dimethylhydroxyethylamine) (p-methoxybenzyl) hydroxyl] its main use is to play a key role in many fields. In the field of medicine, this compound can be used as a key intermediate to help synthesize drugs with specific pharmacological activities. With its unique chemical structure, it participates in the construction of drug molecules, or affects the interaction between drugs and targets, thereby improving the efficacy and selectivity of drugs.
    In the field of materials science, it may be used to prepare special polymer materials. Because its contained groups can polymerize with other monomers, giving materials special properties, such as improving the solubility and thermal stability of materials, or making them have special optical and electrical properties, it is widely used in electronic devices, optical materials, etc.
    In the field of fine chemicals, this substance can be used as an additive to optimize product performance. Added to coatings, it may enhance coating adhesion and weather resistance; used in plastic processing, it may improve the flexibility and anti-aging properties of plastics.
    Just as "Tiangong Kaiwu" said, everything in the world has its uses. Although this compound has a complex structure, it can be skillfully used in different industries to bring many conveniences and innovations to mankind. With its unique chemical structure and properties, it has exerted its strengths in the fields of medicine, materials, fine chemicals, etc., injecting vitality into the development of various industries, promoting technological progress and product upgrading.
    What are the synthesis methods of 2- [ (2-dimethylaminoethyl) (p-methoxybenzyl) amino] pyridine
    To prepare a compound of 2 - [ (2 - dimethylaminoethyl) (p-methoxybenzoyl) amino], the synthesis method is as follows:
    Start with p-methoxybenzoic acid, and make it co-heat with thionyl chloride to obtain p-methoxybenzoyl chloride. This step of reaction needs to be controlled at an appropriate temperature range and carried out in a well-ventilated place to avoid harmful gases.
    Take 2 - dimethylaminoethanol and dissolve it in an appropriate amount of organic solvent, such as dichloromethane or tetrahydrofuran. Slowly drop in the pre-prepared p-methoxybenzoyl chloride, and at the same time adjust the pH value of the reaction system with alkali such as triethylamine to maintain a weakly alkaline environment to promote the reaction. This process is suitable for operation at low temperature, usually controlled at 0-5 ° C, and constantly stirring to fully contact the reactants.
    When the dropwise addition is completed, the temperature is raised to room temperature, and the reaction number is continuously stirred. Monitor the reaction progress by thin layer chromatography until the raw material point disappears, indicating that the reaction is complete.
    After the reaction is completed, pour the reaction solution into an appropriate amount of dilute acid solution, such as dilute hydrochloric acid, to wash away the unreacted base. Separate the organic phase and dry it with anhydrous sodium sulfate to remove the moisture. The crude product was then distilled under reduced pressure to remove the organic solvent.
    The crude product was purified by column chromatography. Silica gel was used as the stationary phase, and the mixture of petroleum ether and ethyl acetate in an appropriate proportion was selected as the mobile phase. The target fraction was collected to obtain a pure 2- [ (2-dimethylaminoethyl) (p-methoxybenzoyl) amino] product.
    There are other ways to prepare this product. For example, p-methoxybenzaldehyde is used as the starting material, and p-methoxybenzyl is obtained by oximation reaction, and then p-methoxybenzyl amine is obtained by reduction. After the reaction with 2-chloroethyl dimethylamine hydrochloride under the action of alkali, the target product can also be obtained. However, this route step is slightly complicated and some reaction conditions are harsh, so careful operation is required.
    What are the physical properties of 2- [ (2-dimethylaminoethyl) (p-methoxybenzyl) amino] pyridine
    2-%5B%282-%E4%BA%8C%E7%94%B2%E5%9F%BA%E6%B0%A7%E5%9F%BA%E4%B9%99%E5%9F%BA%29%28%E5%AF%B9%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%84%E5%9F%BA%29%E6%B0%A7%E5%9F%BA%5D this compound, it is a complex structure in the field of organic chemistry. Many characteristics of its physical properties can be understood from its structural fragments.
    First, looking at its structure, it contains a variety of specific functional groups, which cause it to have a certain polarity. For example, some parts such as (2-dimethylhydroxyethyl) and (p-methoxyphenyl) oxygen groups have uneven electron cloud distribution due to atomic electronegativity differences, resulting in molecular polarity. This polarity makes the compound soluble in polar solvents. For example, in polar organic solvents such as ethanol, it can attract solvent molecules through intermolecular forces, such as hydrogen bonds, dipole-dipole interactions, etc., and thus be soluble.
    Secondly, its molecular structure is relatively large and complex, and the intermolecular force is strong. This strong intermolecular force causes the melting point and boiling point of the compound to be relatively high. To make the molecule overcome the intermolecular force and melt or vaporize, more energy is required, so the melting point is higher than that of the compound with simple structure.
    Furthermore, in view of the existence of aromatic rings and other parts in its structure, the compound is endowed with certain stability. The aromatic ring has a conjugated system, electron delocalization, reducing molecular energy and enhancing stability. This makes the compound less prone to chemical reactions under general conditions and has good chemical stability.
    Finally, from the perspective of the overall molecular shape, its shape is irregular, which affects the way the molecules are packed, which in turn affects physical properties such as crystal structure and density. Irregular shapes make molecules pack less tightly in the crystal than regular shapes, which may lead to relatively low densities and other situations.
    What are the chemical properties of 2- [ (2-dimethylaminoethyl) (p-methoxybenzyl) amino] pyridine
    The chemical substances involved in the 2-%5B%282-%E4%BA%8C%E7%94%B2%E5%9F%BA%E6%B0%A7%E5%9F%BA%E4%B9%99%E5%9F%BA%29%28%E5%AF%B9%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%84%E5%9F%BA%29%E6%B0%A7%E5%9F%BA%5D have a variety of chemical properties.
    This substance exhibits unique reactivity due to the presence of specific groups. Such as (2-dimethoxyethoxy), the structure of this part is relatively stable, but under certain conditions, in case of strong oxidizing agents, oxidation reactions may occur, causing the oxygen group to change and form new oxygen-containing compounds. The (p-methoxybenzyl) part, because of its phenyl ring structure and oxygen group, makes the group have both the aromaticity of the benzene ring and the nucleophilicity due to the presence of the oxygen group. Under the action of an appropriate catalyst, it can be substituted with electrophilic reagents, and the hydrogen atom on the benzene ring is replaced by other groups to form more complex compounds.
    Furthermore, the oxygen group in this substance can participate in a variety of reactions. Under acidic conditions, protonation may occur, enhancing its electrophilicity, and then triggering a series of nucleophilic substitution or elimination reactions. For example, when reacting with compounds containing hydroxyl groups, ether bonds may be formed to construct new molecular structures. At the same time, the overall structure of the substance makes it potentially valuable in the field of organic synthesis. It can be used as an important intermediate for the preparation of organic compounds with biological activities or special functions.
    In addition, its solubility is also worthy of attention. Due to the presence of both hydrophilic oxygen groups and hydrophobic hydrocarbon structures in the molecule, the solubility varies in different solvents. In polar organic solvents such as ethanol and acetone, there may be a certain solubility; in non-polar solvents such as n-hexane, the solubility may be lower. This solubility characteristic needs to be considered in its separation, purification and reaction system selection.
    What is the market outlook for 2- [ (2-dimethylaminoethyl) (p-methoxybenzyl) amino] pyridine?
    Today, there are di- [ (di-dimethylhydroxyethyl) (p-methoxybenzyl) hydroxyl], what is the market prospect?

    This di- [ (di-dimethylhydroxyethyl) (p-methoxybenzyl) hydroxyl], in the current world, its market prospect is related to many factors, which are complex and cannot be asserted immediately.
    From the perspective of industrial application, if this compound can provide a unique path for the synthesis of new materials in the field of chemical synthesis, or make the material have unique characteristics, such as higher stability, stronger corrosion resistance, and even unique optical and electrical properties, it will definitely attract the attention of the materials science community. The chemical industry has always sought innovation and change. If it can emerge in the improvement of materials, it will attract many chemical companies to compete for research and development and utilization, and the market prospect will be broad.
    In terms of medicine, if this compound is helpful for the treatment of specific diseases, or opens up a new path for drug research and development, with its unique chemical structure, it can precisely act on human diseased cells, and the side effects are small, then the pharmaceutical market will definitely open the door for it. In today's pharmaceutical industry, there is a hunger for high-efficiency and low-toxicity new drugs. If this product can meet this demand, the market potential is limitless.
    However, there are also many challenges ahead. First, the preparation process may be complex and expensive. If it is difficult to achieve large-scale, low-cost production, even if the performance is excellent, it is difficult to be widely circulated in the market. Second, market awareness is also key. For a new compound to be recognized, it needs to be verified by long-term research, and it also needs a process for companies and scientific research institutions to understand and accept it. Third, regulatory supervision is also constrained. In fields with strict safety requirements, such as medicine and food, it needs to be heavily approved before it can be put into the market.
    In summary, although di- [ (di- dimethylhydroxyethyl) (p-methoxybenzyl) hydroxyl] has potential advantages, it is necessary to overcome various problems such as preparation, cognition, and supervision in order to open up a bright future.