2 2 6 2 Terpyridine 4 4 4 Tricarboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,2':6',2''-terpyridine-4,4',4''-tricarboxylic acid

    Specifications

    HS Code

    472838

    Chemical Formula C18H11NO6
    Molecular Weight 337.28 g/mol
    Appearance Solid
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO
    Pka Values Multiple pKa values due to carboxylic acid groups
    Crystal Structure Complex structure determined by X - ray crystallography
    Coordination Ability Can act as a tridentate ligand to bind metal ions

    As an accredited 2,2':6',2''-terpyridine-4,4',4''-tricarboxylic acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive 2,2':6',2''-terpyridine-4,4',4''-tricarboxylic acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy 2,2':6',2''-terpyridine-4,4',4''-tricarboxylic acid in China?
    As a trusted 2,2':6',2''-terpyridine-4,4',4''-tricarboxylic acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,2':6',2''-terpyridine-4,4',4''-tricarboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acid?
    2%2C2%27%3A6%27%2C2%27%27-%E4%B8%89%E8%81%94%E5%90%A1%E5%95%B6 and 4%2C4%27%2C4%27%27-%E4%B8%89%E7%BE%A7%E9%85%B8%E7%9A%84 are both important categories of organic compounds, and their chemical structures are very delicate and valuable to explore.
    2%2C2%27%3A6%27%2C2%27%27-%E4%B8%89%E8%81%94%E5%90%A1%E5%95%B6, composed of three pyridine rings closely connected by specific chemical bonds. As a kind of nitrogen-containing six-membered heterocyclic ring, the pyridine ring is aromatic. In this compound, the angle and position of the pyridine ring connection give it a unique spatial structure. The nitrogen atom on each pyridine ring has a profound impact on the electron cloud distribution and chemical activity of the whole molecule due to its electronegativity and the existence of lone pair electrons. This structure makes the compound exhibit excellent properties in the field of coordination chemistry. It can be used as a ligand to form stable complexes with various metal ions, and has wide applications in catalysis, materials science, and many other aspects.
    As for 4%2C4%27%2C4%27%27-%E4%B8%89%E7%BE%A7%E9%85%B8, three carboxyl groups are connected to a specific skeleton structure. Carboxyl (-COOH) is an extremely important functional group in organic chemistry, which has both acidity and the ability to form hydrogen bonds. In this compound, the spatial distribution of the three carboxyl groups and the interaction with the skeleton determine its physical and chemical properties. The acidity of the carboxyl group allows it to react with acid and base under suitable conditions, and can bind to other molecules through hydrogen bonding, which is of key significance in supramolecular chemistry and drug design. The characteristics of its skeleton structure also affect the stability and solubility of the whole molecule, laying the foundation for its application in different fields.
    In short, the chemical structures of the two are unique, and in-depth study of them will surely bring new opportunities and breakthroughs to the development of many scientific fields.
    2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acids What are the common application fields?
    2%2C2%27%3A6%27%2C2%27%27-%E4%B8%89%E8%81%94%E5%90%A1%E5%95%B6 - 4%2C4%27%2C4%27%27-%E4%B8%89%E7%BE%A7%E9%85%B8%E6%9C%89%E5%93%AA%E4%BA%9B%E5%B8%B8%E8%A7%81%E7%9A%84%E5%BA%94%E7%94%A8%E9%A2%86%E5%9F%9F%EF%BC%9F This is to inquire about the common application field of 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acid. The following is answered in the form of classical Chinese.
    Fu 2,2': 6 ', 2' -tripyridine-4,4 ', 4' -tricarboxylic acid, which is widely used in various fields of chemistry. First, in the genus of coordination chemistry, it is often a ligand. Due to its unique structure, it can complex with many metal ions to form stable coordination compounds. This ligand is of extraordinary use in the field of catalysis. For example, in organic synthesis reactions, it can be used as a high-efficiency catalyst to accelerate the reaction process, improve the reaction yield, and have good selectivity, making the reaction more controllable.
    Second, it also has important applications in the field of materials science. It can be used to coordinate with metal ions to construct metal-organic framework materials (MOFs). Such materials have a high specific surface area and a regular pore structure. Therefore, it performs well in gas adsorption and separation. For example, the adsorption of carbon dioxide, hydrogen and other gases can achieve efficient separation and storage, which is of great significance in the fields of energy and environmental protection.
    Furthermore, it can also play a role in the field of fluorescence sensing. Due to their unique fluorescent properties, coordination compounds can respond to specific ions or molecules, resulting in changes in fluorescence intensity or wavelength. With this property, sensitive fluorescent sensors can be designed for detecting environmental pollutants, biomolecules, etc., to assist environmental monitoring and biomedical research.
    In summary, 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acids are important chemical substances in catalysis, materials science, fluorescence sensing and other fields, and their application prospects are broad. They are indispensable for chemical research and industrial production.
    What are the synthesis methods of 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acid?
    To prepare 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acid, there are many methods.
    First, start with pyridine compounds. First take a suitable pyridine derivative, through halogenation reaction, the pyridine ring is introduced into a halogen atom at a specific position. Commonly used halogenating agents include hydrogen halide, phosphorus halide, etc. Subsequently, through metal-catalyzed coupling reactions, such as palladium-catalyzed Suzuki coupling, Stille coupling, etc., the halogen-containing pyridine derivative is connected with a suitable boric acid or tin reagent to construct a tripyridine skeleton. After the tripyridine structure is obtained, the carboxylation reaction is carried out. Strong oxidants, such as potassium permanganate, can be used to oxidize the side chain at a specific position on the pyridine ring to a carboxyl group; carbon dioxide can also be used as a carboxyl group source to achieve carboxylation under suitable metal catalysts and basic conditions, so as to obtain the target product.
    Second, start from simple aromatic compounds. For example, using benzene derivatives as starting materials, the pyridine ring is first constructed through a multi-step reaction. Pyridine rings can be condensed under acidic conditions by Hantzsch reaction, using aldehyde, β-ketoate and ammonia as raw materials. After that, through a coupling and carboxylation reaction similar to the above, the pyridine ring is gradually introduced and a carboxyl group is formed, resulting in 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acid.
    Third, the intramolecular cyclization strategy is adopted. A chain compound with a suitable functional group is selected, and under specific reaction conditions, the cyclization reaction occurs in the molecule to form a pyridine ring. For example, the pyridine ring structure is constructed by reactions such as intramolecular nucleophilic substitution and cyclization dehydration, and then modified by coupling and carboxylation to achieve the synthesis of the target product.
    What are the physical and chemical properties of 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acids?
    2%2C2%27%3A6%27%2C2%27%27-%E4%B8%89%E8%81%94%E5%90%A1%E5%95%B6 - 4%2C4%27%2C4%27%27-%E4%B8%89%E7%BE%A7%E9%85%B8%E7%9A%84%E7%89%A9%E7%90%86%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E6%9C%89%E5%93%AA%E4%BA%9B%EF%BC%9F%3F%2C this is 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acid related questions, the following classical Chinese form to answer its physical and chemical properties.
    2,2': 6 ', 2' -tripyridine-4,4 ', 4' -tricarboxylic acid, this substance is mostly solid form at room temperature, and it is often powdery in appearance, white or nearly white in color, delicate and uniform in quality. Its solubility is quite characteristic. In water, the state of dissolution is limited, and the polarity and water molecules do not match completely because of their molecular structure. However, in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF) and other polar organic solvents, the dissolution situation is better, and it can be fused with it to form a uniform dispersion system.
    When it comes to chemical properties, the carboxyl group (-COOH) in this compound exhibits reactivity. The carboxyl group can be neutralized with the base under suitable conditions to form the corresponding carboxylate and water. For example, in the case of sodium hydroxide (NaOH), the hydrogen of the carboxyl group dissociates and combines with the hydroxyl ion (OH) to form water, while the carboxyl group is converted into a carboxyl negative ion and forms a sodium carboxylate salt with the sodium ion (Na).
    Furthermore, the 2,2 ': 6', 2 '-tripyridine part has a certain coordination ability due to the nitrogen-containing heterocyclic structure. Nitrogen atoms have lone pairs of electrons, which can coordinate with metal ions to form stable complexes. This property has potential application value in materials chemistry, catalytic chemistry and other fields. After metal ions coordinate with the compound, the physical and chemical properties of the system often change significantly, such as color, magnetic, optical properties, etc., which can provide opportunities for the creation and performance regulation of new materials.
    What is the unique role of 2,2 ': 6', 2 '-tripyridine-4,4', 4 '-tricarboxylic acids in materials science?
    2%2C2%27%3A6%27%2C2%27%27-%E4%B8%89%E8%81%94%E5%90%A1%E5%95%B6 and 4%2C4%27%2C4%27%27-%E4%B8%89%E7%BE%A7%E9%85%B8 in the field of materials science, each has its own unique uses.
    2%2C2%27%3A6%27%2C2%27%27-%E4%B8%89%E8%81%94%E5%90%A1%E5%95%B6, its structure is special, with unique electronic and spatial characteristics. In material synthesis, it can be used as an excellent template to guide the formation of materials with specific structures. For example, when preparing ordered mesoporous materials, with its special spatial configuration, the pore size and shape can be precisely adjusted, so that the material has a high specific surface area and a regular pore structure, which shines in the field of catalysis and adsorption. In the catalytic reaction, it provides a suitable reaction site for the reactants, accelerates the reaction process, and improves the catalytic efficiency; during the adsorption process, the large specific surface area and regular pore channels are conducive to the rapid diffusion and adsorption of adsorbates, and the adsorption effect on harmful gases and heavy metal ions is quite good.
    Furthermore, 2%2C2%27%3A6%27%2C2%27%27-%E4%B8%89%E8%81%94%E5%90%A1%E5%95%B6 can enhance the mechanical properties of materials. Adding polymer materials, by virtue of its interaction with polymer molecules, build a three-dimensional network structure, strengthen the internal connection of materials, improve the strength and toughness of materials, and is of great significance in aerospace, automobile manufacturing and other fields that require strict mechanical properties of materials.
    4%2C4%27%2C4%27%27-%E4%B8%89%E7%BE%A7%E9%85%B8, due to the presence of carboxyl groups in the molecule, it gives it good hydrophilicity and reactivity. In the field of coatings and adhesives, it can improve the adhesion of materials to substrates. By means of the interaction between carboxyl groups and hydroxyl groups on the surface of the substrate, metal ions, etc., a stable chemical bond or physical adsorption is formed to ensure that the coating, adhesive and substrate are closely combined, and the service life and stability of the material are improved.
    In addition, 4%2C4%27%2C4%27%27-%E4%B8%89%E7%BE%A7%E9%85%B8 can participate in the material crosslinking reaction. React with compounds containing active groups to build a three-dimensional cross-linking network and change the physical and chemical properties of the material. For example, when preparing hydrogel materials, a network structure with certain strength and swelling properties is formed through cross-linking reaction. In the field of biomedicine, it can be used as a drug sustained-release carrier, tissue engineering scaffold, etc., to achieve controlled drug release according to its own swelling characteristics and provide a suitable microenvironment for cell growth.