2-(2,4-difluorophenyl)pyridine

The main uses of (2,4-diethylamino) benzene are as follows:
This compound is often a key intermediate in the field of medicine. Due to its specific chemical structure, it can interact with many substances in the biological body. For example, in the synthesis of some cardiovascular drugs, (2,4-diethylamino) benzene can be reacted through a series of reactions to build a core structure of drug activity, which can help the drug accurately act on the target of the cardiovascular system, or regulate blood pressure, or improve heart rhythm.
In the dye industry, it also plays an important role. Due to its unique optical properties, it can absorb and reflect specific wavelengths of light, resulting in rich color. The dyes prepared by it have good affinity for various fiber materials, and the dyed fabrics have bright colors and good fastness. They are widely used in textile printing and dyeing. Whether it is cotton clothing or silk products, they can be dyed with this dye.
In the field of organic synthesis, (2,4-diethylamino) benzene is like a cornerstone. Its active chemical groups can trigger a variety of chemical reactions, such as nucleophilic substitution, addition, etc., providing the possibility to construct complex organic molecules. Chemists can use this to synthesize organic materials with special functions, either for electronic devices or in the field of catalysis, to expand the boundaries of organic synthesis and promote the progress of materials science.

The synthesis methods of 2 - (2,4 - diethylamino) benzaldehyde are as follows:
** 1. Oxidation method with 2,4 - diethylamino toluene as raw material **
1. ** Principle **: 2,4 - diethylamino toluene under the action of appropriate oxidant, its methyl group can be oxidized to aldehyde group.
2. ** Step **: First, 2,4 - diethylamino toluene is placed in a reactor, dissolved in an appropriate amount of organic solvent such as dichloromethane, and then slowly added with a diluted strong oxidant such as potassium dichromate sulfuric acid solution. The reaction needs to be carried out at low temperature and stirred to prevent excessive oxidation. After the reaction is completed, the product is separated and purified by extraction, distillation and other means. Although this method is easy to obtain raw materials, the selection and dosage of oxidizing agent need to be carefully controlled, otherwise it is easy to produce by-products and affect the purity of the product.
* 2. Reduction method with 2,4-diethylaminobenzoic acid as raw material **
1. ** Principle **: The carboxyl group in 2,4-diethylaminobenzoic acid is reduced to an aldehyde group by using a reducing agent.
2. ** Step **: Put 2,4-diethylaminobenzoic acid and a suitable reducing agent, such as lithium aluminum hydride, into the reaction vessel in a certain proportion, and use anhydrous ether as the solvent. The reaction needs to be carried out in an anhydrous and oxygen-free environment, and the temperature is controlled within an appropriate range. After the reaction is completed, the target product is obtained by hydrolysis, extraction and other operations. The advantage of this method is that the reaction conditions are relatively mild, but the price of reducing agents such as lithium aluminum hydride is higher, and the operation needs to be strictly isolated from water vapor and air, which requires high operation.
** Third, the substitution method using benzaldehyde derivatives as raw materials **
1. ** Principle **: Through the substitution reaction, the specific position on the benzaldehyde ring in the benzaldehyde derivative is replaced by a diethylamino group, thereby obtaining 2 - (2,4 - diethylamino) benzaldehyde.
2. ** Step **: Select a suitable benzaldehyde derivative, such as 2-chlorobenzaldehyde, and react with diethylamine in an organic solvent under alkali catalysis. Potassium carbonate can be selected for the base, and N, N-dimethylformamide can be selected for the solvent. The reaction is carried out under the condition of heating and reflux, and the reaction time needs to be determined according to the actual situation. After the reaction, the product is separated by neutralization, extraction, column chromatography and other steps. This method has good selectivity, but the selection of raw materials and the optimization of reaction conditions have a significant impact on the yield of the product.

The physical properties of (2,4-diethylamino) benzene are as follows:
The outer surface is usually light to brown oily liquid. Smell it, it has a special smell. Under normal conditions, the phase density of this liquid is slightly higher than that of water, which is between 1.01 and 1.05. If it is placed in water, it will sink to the bottom of the water. Its boiling height is 260-270 ° C, indicating that a high temperature is required to make it melt from the liquid. The melting phase is low, about -50 ° C, that is, in a low temperature environment, this material can still hold liquid.
Furthermore, (2,4-diethylamino) benzene is slightly soluble in water, which is determined by its molecular properties. The diethylamino group contained in its molecule makes the molecule whole. It is oily to a certain extent, so its solubility in water is limited. However, it is soluble in many soluble substances, such as ethanol, ether, acetone, etc., and can be well dispersed and dissolved in this solution. The solubility of benzene is significant in the synthesis and engineering of benzene.
In addition, this substance has a certain resistance, and its boiling temperature is high. However, under normal conditions, some molecules still escape from the surface and disperse in the surrounding air. And because of its durability and special taste, it is necessary to pay attention to safety measures such as safety measures in use and storage to prevent the environment and users from causing adverse effects. Moreover, (2,4-diethylamino) benzene has many physical properties, and various properties interact with each other, which together affect its behavior under different conditions.

There is (2,4-diethylamino) now. In the price range on the market, I will try to analyze it for you.
The price of various things in Guanfu City often varies for many reasons. The price of this (2,4-diethylamino) product depends on the availability of raw materials, the difficulty of preparation, the amount required, and the supply and demand in the market.
If the raw materials are easy to produce, the method of preparation is simple and convenient, and the demand is scarce, the supply exceeds the demand, the price will be cheap. Or the spectrum of tens of dollars to one or two hundred dollars.
On the contrary, if the raw materials are rare, the production is complicated, and everyone wants them, and the supply is in short supply, the price will be high. Or it can reach hundreds of dollars, or even more than a thousand dollars is unknown.
However, if you want to know the exact price, you need to carefully observe the current market situation, visit merchants and experts, and study the price of raw materials and the improvement of craftsmanship in detail before you can make a more accurate decision.
Roughly speaking, its price may be in the range of tens of dollars to thousands of dollars, which is difficult to determine quickly. Because the market conditions are fickle and various factors interact.

Those who store (di, tetra- diethylamino) benzene should pay attention to the general situation. Such substances may have special properties, so they exist in a place where things are dry and dry. In the environment of tides, or cause their properties to change, resulting in similar drawbacks.
And it is appropriate to place it in a place where it is not exposed to the hot sun. Under the high temperature, this (di, tetra- diethylamino) benzene may be at risk of burning, or it may be induced to react, causing it to fail.
In addition, the storage device also needs to be appropriate. Use dense compatibility to prevent it from being connected in the air. In the air, oxygen, water vapor and other substances may act on it, which affects its original nature.
It is also necessary to pay attention to the source of ignition and flammable materials. (Di-, tetra- diethylamino) benzene may be flammable. If it is close to the source of ignition, it will be dangerous and endanger the safety of the surrounding area.
To save (di-, tetra- diethylamino) benzene, it must be dry and dry, and it must be used in secret devices, and it must be flammable materials with fire sources. In this way, its properties can be guaranteed, and there is no risk of safety.