2 1h Pyridine 3 Chloro 5 6 Dihydro 1 4 Nitrophenyl
pyridine pyrrole pyrazine piperidine piperazine

2(1H)-pyridine, 3-chloro-5,6-dihydro-1-(4-nitrophenyl)-

    Specifications

    HS Code

    601123

    Chemical Formula C11H11ClN2O2
    Molecular Weight 238.67

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 2 (1H) -pyridine, 3-chloro-5,6-dihydro-1- (4-nitrophenyl) -?
    Eh! The physicochemical production of Ximing 2- (2-pyridyl) -3-chloro-5,6-dihydro-1- (4-nitrophenyl) is the key to chemical production. Let me tell you.
    This product is also the pyridyl group, which contains nitrogen hexagonal aromatics, which has the reaction activity of the special molecular component. 2 - (2-pyridyl), the second main phase of pyridine. In the main layer, 3-chlorine, the chlorine atom is connected to the third position of the main layer, and the chlorine atom is active, which can often be replaced and eliminated like a chemical.
    Furthermore, 5, 6-two, table 5 and 6 of the main positions are the original ones, which are already the original ones. These two factors increase the sum of molecules, and the properties are also the original ones.
    And 1 - (4-nitrophenyl), is the first position of benzene, and the fourth position of benzene has a nitro group. Nitro-absorbing groups can affect the cloud density of benzene and change the reaction activity of benzene.
    The chemical composition of this substance is composed of a pyridyl group, a chlorine-containing principal group, a diphenyl group, and a nitro-containing benzene group. The various parts interact with each other, which gives the substance its unique chemical properties. Such as its sub-effects, air effects, etc., are all generated by the interaction of various groups, and are used in the fields of synthesis, chemical research, etc., or have important uses.
    2 (1H) -pyridine, 3-chloro-5,6-dihydro-1- (4-nitrophenyl) - what are the physical properties
    3-Chloro-5,6-dihydro-1- (4-nitrophenyl) -2 (1H) -pyridine has a number of physical properties. Its shape may be solid, or it may have a specific color. However, the color may vary depending on the preparation conditions and purity.
    When it comes to melting point, it is actually an important characteristic of a substance. After experimental measurement, its melting point falls within a specific temperature range, which is crucial for the identification and purification of this substance. Under different purity, the melting point may vary slightly, and the melting point of pure people is relatively fixed and accurate.
    The boiling point is also the main consideration. In a specific pressure environment, the substance will reach a boiling point and vaporize. This boiling point value is helpful for understanding its phase transition under different conditions, and is of great significance for separation and purification processes.
    In terms of solubility, it varies in various solvents. In organic solvents such as ethanol and ether, it may have a certain solubility, while in water, the solubility may be limited. This characteristic is related to its application in solution systems. For example, in chemical reactions, the choice of solvent depends on its solubility in order to make the reaction proceed smoothly.
    Density is also one of its physical properties. Under a specific temperature and pressure, its density has a certain value, which provides an important reference for measuring the proportion and distribution of the substance in the mixture, and is crucial in the material ratio of chemical production and scientific research experiments.
    In addition, the refractive index of the substance reflects its ability to refract light. Accurate determination of refractive index helps to determine its purity and concentration, which is an important indicator in the field of quality control and analytical testing.
    In summary, the many physical properties of 3-chloro-5,6-dihydro-1- (4-nitrophenyl) -2 (1H) -pyridine play a key role in many fields such as chemical industry and scientific research. In-depth understanding of these properties can better apply this substance.
    What is the main use of 2 (1H) -pyridine, 3-chloro-5,6-dihydro-1- (4-nitrophenyl) -?
    3-Chloro-5,6-dihydro-1- (4-nitrophenyl) -2 (1H) -pyridine has a wide range of uses. In the field of medicine, it is often a key intermediate in the synthesis of many specific drugs. Its unique chemical structure can be modified by delicate chemistry to derive compounds with specific pharmacological activities, or have antibacterial and anti-inflammatory properties, or have targeted therapeutic effects on specific diseases, adding powerful means for doctors to heal patients.
    In the field of materials science, it also plays an important role. Because it contains specific functional groups and structural properties, it can be used as the cornerstone of functional material synthesis. By compounding or modifying with other materials, materials can obtain unique electrical, optical or mechanical properties, such as for the preparation of special conductive materials, optically sensitive materials, etc., to help material innovation and promote the progress of related industries.
    On the road of scientific research and exploration, as an important research object of organic synthetic chemistry, it provides opportunities for chemical researchers to study new reaction mechanisms and explore new synthesis paths. Its complex structure and diverse reactivity attract scholars to explore in depth, promote the development of organic chemistry theory and practice, and add to the building of chemical science.
    What are the synthesis methods of 2 (1H) -pyridine, 3-chloro-5,6-dihydro-1- (4-nitrophenyl) -
    The synthesis of 3-chloro-5,6-dihydro-1- (4-nitrophenyl) -2 (1H) -pyridine is an important topic in organic synthesis. In the past, Zhu Xian had overcome obstacles in organic synthesis and explored many paths.
    One of the methods may be initiated by suitable pyridine derivatives. Choose a pyridine parent whose structure contains a modifiable check point. First introduce chlorine atoms at specific positions on the pyridine ring in an exquisite way. For example, a pyridine containing active hydrogen, in a specific reaction medium, meets with a suitable chlorination reagent, or under catalytic conditions, makes the chlorine atom fall precisely in the required 3 positions of the pyridine ring.
    Then, the 5,6 positions of the pyridine ring are dihydrogenated. In this step, a suitable hydrogenation reagent may be selected to partially hydrogenate the double bond of the pyridine ring at a suitable temperature, pressure and in the presence of a catalyst, to obtain the structure of 5,6-dihydropyridine.
    Furthermore, a 1 - (4-nitrophenyl) group is to be introduced. It can make 5,6-dihydro-3-chloropyridine and reagents containing 4-nitrophenyl group in alkaline environment or specific catalytic system, through nucleophilic substitution and other reactions, so that 4-nitrophenyl group can be attached to the first position of pyridine.
    There may also be other methods. First construct the active intermediate containing 4-nitrophenyl group, and then cyclize it with pyridine related precursors to gradually construct the structure of the target molecule. The synthesis method varies widely, and the optimal method needs to be weighed according to many factors such as the availability of raw materials, the difficulty of reaction and the high or low yield.
    What are the characteristics of 2 (1H) -pyridine, 3-chloro-5,6-dihydro-1- (4-nitrophenyl) -in chemical reactions
    3-Chloro-5,6-dihydro-1- (4-nitrophenyl) -2 (1H) -pyridine has many unique properties in chemical reactions. In its structure, the pyridine ring is the key part, and the substitution of the chlorine atom with the nitrophenyl group endows the compound with specific electronic effects and steric resistance.
    From the perspective of reactivity, the nitrogen atom on the pyridine ring has a lone pair of electrons, which can be used as an electron donor and easily reacts with electrophilic reagents. The strong electron-absorbing properties of 4-nitrophenyl group can reduce the electron cloud density on the pyridine ring, especially the electron cloud density of the ortho and para-site changes significantly, and the electrophilic substitution reaction is more likely to occur in the meta-site.
    In the nucleophilic substitution reaction, the chlorine atom can be replaced by the nucleophilic reagent because of its certain ability to leave. Due to the existence of the pyridine ring and the nitrophenyl conjugate system, the substitution reaction activity is synergistically affected by the electronic effect of the two.
    Furthermore, the 5,6-dihydro structure part has different reactivity relative to the unsaturated structure of the pyridine ring. This dihydro structure is more susceptible to the attack of oxidizing agents or electrophilic reagents, triggering
    In addition, due to the nitro group content, the compound can undergo characteristic reactions such as nitro reduction and be converted into amino-containing compounds, expanding its application scope in organic synthesis and providing a basis for the construction of more complex organic molecules.
    In summary, 3-chloro-5,6-dihydro-1- (4-nitrophenyl) -2 (1H) -pyridine has important research and application value in the field of organic synthesis due to its unique structure.