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What is the chemical structure of 2- { (1E) -N- [ (3,5-difluorophenyl) aminoformyl] ethanohydrazone} pyridine-3-carboxylic acid
The chemical structure of this compound is analyzed as follows:
First, the complex expression given in the title is gradually disassembled. "2- { (1E) -N- [ (3,5-divinylphenyl) carbamyl] ethylchloroformyl} pyridine-3-carboxylic acid", starting from the main chain structure, the pyridine ring is one of the core skeletons of this compound. A complex substituent is connected at position 2 on the pyridine ring, and a carboxyl group is connected at position 3.
For the substituent at position 2, first look at "{ (1E) -N - [ (3,5 -divinylphenyl) carbamyl methyl] ethylchloroformyl}". (1E) indicates the presence of a double bond in the E configuration, which should be in the long chain of the substituent. The N atom is connected to two parts, one is "[ (3,5-divinylphenyl) carbamoyl methyl]", that is, 3,5-divinylphenyl is connected to N through carbamoyl methyl, which is -CONHCH ² - structure; the other part is "ethylchloroyl", that is, -COCH ² CH ² Cl structure.
As a whole, this compound is centered on a pyridine ring, with a complex structure of the substituent at position 2, containing a specific configuration of double bonds, benzene rings, and a variety of functional group connection structures. Position 3 is a carboxyl group. Its chemical structure is unique, and the functional groups of each part interact with each other, which determines the specific physicochemical properties and possible chemical reactivity of the compound.
What are the main uses of 2- { (1E) -N- [ (3,5-difluorophenyl) carbamoyl] ethanhydrazone} pyridine-3-carboxylic acids
2-% { (1E) -N- [ (3,5-diethylphenyl) oxyaminoacetyl] ethylguanidine} to its -3-carboxylic acid, this substance has a wide range of uses. It is used in the field of medicine and can be used to develop specific drugs. Due to its unique chemical structure, it may have an effect on specific physiological mechanisms of the human body, such as participating in the reaction regulation of certain enzymes, or binding to specific receptors, which can be helpful in the treatment of diseases, or can be used in the development of antibacterial and antiviral drugs, by interfering with the metabolism or reproduction process of pathogens to achieve therapeutic purposes.
In the chemical industry, this compound can be used as an important intermediate. With its chemical activity, it can react with a variety of other compounds to build more complex organic structures, which can be used to synthesize new materials, such as polymer polymers with special properties. It may have applications in coatings, plastics and other industries, giving materials unique physical and chemical properties, such as enhancing material stability, corrosion resistance, etc.
In the field of scientific research and exploration, it is an important research object. By studying its chemical properties and reaction mechanism, researchers can gain a deep understanding of the relevant reaction laws in the field of organic chemistry, provide theoretical basis and practical experience for the development of organic synthetic chemistry, promote the further development of chemistry, or provide new ideas and methods for research in other fields.
What is the synthesis method of 2- { (1E) -N- [ (3,5-difluorophenyl) aminoformyl] ethanhydrazone} pyridine-3-carboxylic acid
To prepare 2- { (1E) -N- [ (3,5 -divinylphenyl) aminoethyl] acetamido} -3 -pyridinecarboxylic acid, the following ancient method can be used:
Appropriate starting materials are taken first, in which (1E) -N- [ (3,5 -divinylphenyl) aminoethyl] acetamido-related fragments and pyridinecarboxylic acid parent must be carefully constructed step by step.
For the (1E) -N- [ (3,5-divinylphenyl) aminoethyl] acetamide moiety, 3,5-divinylbenzene can be used as the starting point. Halogenated 3,5-divinylbenzene-aminoethyl derivatives are obtained by introducing halogen atoms into the benzene ring under suitable temperature and reaction conditions through a halogenation reaction, such as with an appropriate halogenating agent. Then, the amino group is acetylated by an acetylation reagent, such as acetic anhydride or acetyl chloride, in the presence of a suitable catalyst such as pyridine, etc., to obtain (1E) -N- [ (3,5-divinylphenyl) aminoethyl] acetamide intermediates.
The pyridine carboxylic acid part can be obtained by the corresponding pyridine derivative through a suitable oxidation reaction, such as with a specific oxidizing agent, in a suitable reaction system, the substituent at a specific position on the pyridine ring is oxidized to a carboxyl group to obtain pyridine carboxylic acid.
Finally, the obtained (1E) -N- [ (3,5-divinylphenyl) aminoethyl] acetamide intermediate and pyridine carboxylic acid are condensed in a suitable organic solvent in the presence of a condensing agent such as dicyclohexylcarbodiimide (DCC) and a catalyst such as 4-dimethylaminopyridine (DMAP), and the two are connected to obtain the target product 2 - { (1E) -N- [ (3,5-divinylphenyl) aminoethyl] acetamido} - 3 -pyridine carboxylic acid. During the entire process, the control of reaction conditions at each step, the proportion of raw materials, and the purification of intermediates are all crucial, and careful operation is required to obtain products with higher yield and purity.
What are the physicochemical properties of 2- { (1E) -N- [ (3,5-difluorophenyl) carbamoyl] ethanohydrazone} pyridine-3-carboxylic acids
2-% { (1E) -N- [ (3,5-divinyl) aminoethylimidazolyl] ethylchlorobenzyl} pyridine-3-carboxylic acid, which is a complex organic compound. Its physicochemical properties are very important for its application in various fields.
From the perspective of physical properties, the state of the compound may be solid, because many organic compounds with such structures are solid at room temperature. Its melting point and boiling point depend on the strength of intermolecular forces. There are many polar groups in the molecule, such as amino, carboxyl, etc. These groups will enhance the intermolecular forces, resulting in relatively high melting points and boiling points. At the same time, its solubility is also affected by molecular polarity. In polar solvents such as ethanol and water, it may have a certain solubility, while in non-polar solvents such as n-hexane, the solubility may be lower.
In terms of chemical properties, the carboxyl group in the compound is acidic and can be neutralized with bases to generate corresponding carboxylic salts. Amino groups are basic and can react with acids. In addition, the double bonds contained in the molecule can undergo addition reactions, such as addition with hydrogen to form saturated compounds, or electrophilic addition with halogens. Imidazolyl, as a nitrogen-containing heterocycle, has certain chemical activity and can participate in various organic reactions, such as nucleophilic substitution reactions. Under suitable conditions, this compound may also undergo esterification reaction, and ester compounds are formed from carboxyl groups and alcohols under the action of catalysts.
What are the market prospects for 2- { (1E) -N- [ (3,5-difluorophenyl) aminoformyl] ethanohydrazone} pyridine-3-carboxylic acids?
Today, there is a market prospect for 2 - { (1E) -N- [ (3,5 -diethylphenyl) aminoethylformamido] ethylchloroformyl} to its 3-carboxylic acid, just like what Tiangong Kaiwu said, I should describe it in ancient Chinese.
The preparation method of this chemical product requires exquisite skills and the use of raw materials must also be appropriate. 2 - { (1E) -N - [ (3,5 -diethylphenyl) aminoethylformamido] ethylchloroformyl} to its - 3 -carboxylic acid, in today's world, the market is like a boat sailing in the sea, and its prospects include both opportunities and challenges.
In terms of opportunities, today's pharmaceutical and chemical industries are developing rapidly. This acid may be used in the synthesis of drugs and is a key raw material. Nowadays, the world's desire for health is becoming increasingly ardent, and new drug research and development is emerging in an endless stream. If this acid can play a heavy role in the preparation of drugs, assist in the development of drugs, and cure diseases, then its demand will be like the emergence of bamboo shoots, and the market prospect will be broad. And in the chemical industry, the development of fine chemicals is booming, and the demand for various special chemicals is increasing. If this acid has unique characteristics, it is suitable for the production of fine chemicals, and it can also occupy a place in this field and expand the market.
However, challenges also exist. In the chemical synthesis industry, the competition is very fierce. All manufacturers are seeking development, and congeneric products may emerge one after another. If the production cost of this acid is too high, resulting in no price advantage, it will be difficult to compete with other products in the market. And environmental protection regulations are becoming more and more stringent. The process of preparing this acid, if there is a risk of pollution and improper disposal, will be restricted, hindering its production and promotion. Furthermore, the market is changing, and the demand is also changing at any time. If you can't keep up with the trend, understand the needs of the market, adjust production and research and development in a timely manner, or cause the product to be unsalable, the prospect is worrying.
In short, the market prospect of 2- { (1E) -N- [ (3,5 -diethylphenyl) aminoethylformamido] ethylchloroformyl} to its - 3 -carboxylic acid, although there is a bright future, it is necessary to move forward cautiously and deal with various challenges in order to ride the waves in the sea of the market and seek development.