2 1 Bromonaphthalen 2 Yl Oxy Methyl 5 Methylimidazo 1 2 A Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-{[(1-bromonaphthalen-2-yl)oxy]methyl}-5-methylimidazo[1,2-a]pyridine

    Specifications

    HS Code

    285219

    Chemical Formula C21H17BrN2O
    Molecular Weight 393.276
    Appearance Solid (predicted)
    Boiling Point 515.9°C at 760 mmHg (predicted)
    Melting Point 135 - 137°C
    Logp 4.73 (predicted)
    Solubility Soluble in organic solvents like dichloromethane, chloroform (predicted)
    Density 1.44 g/cm³ (predicted)
    Flash Point 265.8°C (predicted)
    Pka No data found for this specific compound

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    Frequently Asked Questions

    As a leading 2-{[(1-bromonaphthalen-2-yl)oxy]methyl}-5-methylimidazo[1,2-a]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2- {[ (1-bromonaphthalen-2-yl) oxy] methyl} -5-methylimidazo [1,2-a] pyridine
    This is an organic compound with a complex chemical structure. According to its naming rules, the structure of "2 - {[ (1-bromonaphthalene-2-yl) oxy] methyl} -5 -methylimidazolo [1,2-a] pyridine" can be known. The main body is the parent nucleus of nimidazolo [1,2-a] pyridine. In its second position, there is an oxygen-containing substituent, which is {[ (1-bromonaphthalene-2-yl) oxy] methyl}, that is, 1-bromonaphthalene-2-yl is connected by an oxygen atom, and the oxygen atom is then connected to the methyl group, and this methyl group is connected to the second position of imidazolo [1,2-a] pyridine. At the 5th position, there is a methyl substitution. In this compound structure, the naphthalene ring contains a fused benzene ring structure, giving it a specific conjugate system and chemical activity. The imidazolo [1,2-a] pyridine parent nucleus has nitrogen heterocyclic properties. The introduction of substituents at different positions alters its electron cloud distribution and spatial structure, affecting its physicochemical properties and biological activities. Overall, the structure design of this compound is exquisite, and the interaction of various parts determines its unique properties and application potential in organic synthesis, medicinal chemistry and other fields.
    What are the main uses of 2- {[ (1-bromonaphthalen-2-yl) oxy] methyl} -5-methylimidazo [1,2-a] pyridine
    2-% 7B% 5B% 281 - bromonaphthalen - 2 - yl%29oxy%5Dmethyl%7D - 5 - methylimidazo%5B1%2C2 - a% 5Dpyridine, this is an organic compound. It has a wide range of uses and plays a key role in different fields.
    In the field of medicinal chemistry, such compounds are often studied as potential drug molecules. Their special chemical structure or endow unique biological activity, which can interact with specific targets in organisms. Or through structural modification and optimization, therapeutics for specific diseases can be developed, such as anticancer drugs, antiviral drugs, etc. Because it can precisely act on the target of diseased cells, it may show high efficiency and specificity in disease treatment.
    In the field of materials science, this compound may become a basic unit for the construction of new functional materials. Due to its structural stability and unique electronic properties, it may be used to prepare optoelectronic materials. In devices such as organic Light Emitting Diodes (OLEDs) and solar cells, key performance indicators such as luminous efficiency and energy conversion efficiency can be improved by virtue of unique optical and electrical properties, providing new ideas for the development of new materials.
    In chemical synthesis research, this compound is also an important synthesis intermediate. Chemists can use various chemical reactions as starting materials to further derive compounds with more complex structures and more diverse functions. By ingeniously designing synthetic routes, the structural diversity of organic compounds can be expanded, contributing to the development of organic synthetic chemistry.
    In short, 2-% 7B% 5B% 281 - bromonaphthalen - 2 - yl%29oxy%5Dmethyl%7D - 5 - methylimidazo%5B1%2C2 - a% 5Dpyridine has important potential uses in many fields such as medicine, materials and chemical synthesis, and is of great significance to promote the development of related fields.
    What is the synthesis method of 2- {[ (1-bromonaphthalen-2-yl) oxy] methyl} -5-methylimidazo [1,2-a] pyridine
    To prepare 2 - { (1-bromonaphthalene-2-yl) oxy] methyl} -5 -methylimidazolo [1,2-a] pyridine, the following ancient method can be carried out.
    First take an appropriate amount of 1-bromonaphthalene-2-alcohol, place it in a clean reactor, use anhydrous ether as a solvent, and slowly add sodium hydride under low temperature and stirring conditions. This step aims to deprotonate the alcohol hydroxyl group to form a nucleophilic reagent. After the reaction is stable and the gas escapes gradually, chloromethyl-5-methylimidazolo [1,2-a] pyridine is dissolved in an appropriate amount of anhydrous ether, and added dropwise to the above reaction system. Add dropwise, heat up to a moderate level, and continue to stir the reaction for several hours. During this process, the nucleophilic reagent generated by 1-bromonaphthalene-2-ol undergoes a nucleophilic substitution reaction with chloromethyl-5-methylimidazolo [1,2-a] pyridine to form the prototype of the target product. < Br >
    After the reaction is completed, pour the reaction solution into a container containing ice water, carefully adjust the pH value with dilute hydrochloric acid to weakly acidic, and stratification can be seen at this time. Take the organic phase and dry it with anhydrous sodium sulfate to remove the water. Then, by reduced pressure distillation, remove the solvent ether to obtain a crude product.
    The crude product needs to be further purified, and column chromatography can be used. Silica gel is used as the stationary phase, and an appropriate amount of petroleum ether and ethyl acetate mixed in a certain proportion is used as the mobile phase. Column chromatography is carried out. Carefully collect the fractions containing the target product, and then remove the solvent by rotary evaporation to obtain pure 2- {[ (1-bromonaphthalene-2-yl) oxy] methyl} -5 -methylimidazolo [1,2-a] pyridine. During the operation, attention should be paid to the control of temperature, pH, and accurate dosage of each reagent, so that the yield can be considerable and the product is pure.
    What are the physical properties of 2- {[ (1-bromonaphthalen-2-yl) oxy] methyl} -5-methylimidazo [1,2-a] pyridine
    2-% 7B% 5B% 281 - bromonaphthalen - 2 - yl%29oxy%5Dmethyl%7D - 5 - methylimidazo%5B1%2C2 - a% 5Dpyridine is an organic compound. The physical properties of this compound are critical to its performance in various chemical processes and practical applications.
    Its appearance is often solid, which gives it a relatively stable physical state, which is more convenient for storage and transportation. The molecular structure is rich in specific atoms and chemical bonds, resulting in a certain melting point. The specific value of this melting point depends on the strength of intermolecular interactions, such as van der Waals forces, hydrogen bonds, etc. Combined effects. When the ambient temperature reaches the melting point, the substance gradually melts from a solid state to a liquid state. This phase transition process is of great significance in material processing and chemical synthesis.
    Solubility is also one of the important physical properties. In organic solvents such as dichloromethane and chloroform, its solubility is good, because its molecular structure is similar to that of organic solvents. However, its solubility in water is poor, due to the large difference between the polarity of water molecules and the molecular polarity of the compound, it is difficult to form an effective interaction.
    In addition, the compound has a certain density, which reflects its mass per unit volume. It is an indispensable parameter when designing the ratio of chemical reaction device to material. Its density value is restricted by molecular mass and molecular accumulation mode.
    Its physical properties are finely regulated by molecular structure, and these properties have a profound impact on its application in organic synthesis, drug development and other fields. Knowing these physical properties will help researchers more accurately control the related chemical processes and achieve the desired chemical transformation and application goals.
    What is the market outlook for 2- {[ (1-bromonaphthalen-2-yl) oxy] methyl} -5-methylimidazo [1,2-a] pyridine
    2-% {[ (1-bromonaphthalene-2-yl) oxy] methyl} -5-methylimidazolo [1,2-a] pyridine, in terms of market prospects, is like a treasure box to be opened. Although it has not been widely praised, it has a hidden brilliance.
    It is in the field of scientific research, or it is a key brick and stone for organic synthesis. The craftsman of organic synthesis often seeks unique structural blocks to build complex and delicate molecular buildings. The special structure of this compound, containing the combination of bromonaphthalene and imidazolopyridine, may be the beginning of a novel reaction path. The activity of its bromine atom is considerable, which can lead to reactions such as nucleophilic substitution, paving the way for the construction of a variety of derivatives. In the direction of new drug molecules and functional material synthesis, it is like uncultivated fertile soil, or a surprise.
    In the field of medicine, or as a hidden drug source. At present, the creation of new drugs is difficult and long, but the unique structure often breeds hope seedlings. The structural characteristics of this compound may be in line with specific targets in organisms. If it can be precisely docked, it may become a sharp blade for disease resistance. Although it has not yet been seen in clinical practice, it has potential value in the process of early drug screening and activity evaluation, providing different ideas for pharmaceutical developers.
    In the field of materials science, there are also opportunities to emerge. With the increasing demand for functional materials, it is urgent to seek substances with specific optoelectronic and thermal properties. Due to its unique molecular structure, or in the field of organic optoelectronic materials, such as Light Emitting Diode, solar cell materials, etc., this compound may bloom with reasonable modification and deployment.
    Although its market awareness is still shallow at present, over time, through the research of researchers and the promotion of industry, it may be able to move from the background to the front of the stage, in the fields of chemical industry, medicine, materials, etc., and become a newcomer in the market.