1h Pyrrolo 2 3 C Pyridine
pyridine pyrrole pyrazine piperidine piperazine

1H-Pyrrolo[2,3-c]pyridine

    Specifications

    HS Code

    668557

    Molecular Formula C7H6N2
    Molar Mass 118.14 g/mol
    Appearance Solid (usually)
    Melting Point Data needed
    Boiling Point Data needed
    Solubility Solubility in common solvents needed
    Density Data needed
    Pka Data needed
    Logp Data needed
    Refractive Index Data needed

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    General Information
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    Frequently Asked Questions

    As a leading 1H-Pyrrolo[2,3-c]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1H-Pyrrolo [2,3-c] pyridine?
    1H-pyrrolido [2,3-c] pyridine is a special organic compound. It has a wide range of uses and can be called a crucial synthesis intermediate in the field of medicinal chemistry. It can be seen in many drug research and development processes. With its unique structure, it can interact with specific targets in organisms, so it is often used as a key starting material or structural fragment when creating drugs with specific biological activities.
    In the field of materials science, it also has important applications. Due to its structural properties, it can endow materials with unique photoelectric properties. For example, it can be used in the synthesis of organic optoelectronic materials to help prepare Light Emitting Diodes, solar cells and other devices to improve the performance of such devices.
    In the field of pesticides, 1H-pyrrolido [2,3-c] pyridine also shows potential value. By modifying and modifying its structure, a new type of pesticide with high efficiency, low toxicity and environmental friendliness can be developed for the control of crop diseases and insect pests, and to ensure the harvest of agricultural production.
    In summary, 1H-pyrrolido [2,3-c] pyridine plays a role that cannot be ignored in many fields such as medicine, materials, and pesticides, and is of great significance to promote the development of related fields.
    What are the physical properties of 1H-Pyrrolo [2,3-c] pyridine
    1H - Pyrrolo [2,3 - c] pyridine is an organic compound with unique physical properties and many applications in chemical synthesis and drug development. The following are its main physical properties:
    - ** Properties **: Under normal conditions, 1H - Pyrrolo [2,3 - c] pyridine is mostly solid. Due to the strong interaction forces between molecules, such as van der Waals forces and hydrogen bonds, the molecules are arranged in an orderly manner to form a solid structure.
    - ** Melting point **: Its melting point is about 130 - 132 ° C. The melting point of the compound is affected by the molecular structure. The molecule has a conjugated system and a rigid structure. The intermolecular force is strong, and a higher temperature is required to destroy the lattice and turn the solid state into a liquid state.
    - ** Boiling point **: The boiling point is about 290-292 ° C. The higher boiling point is also due to the strong intermolecular force. To make it change from liquid state to gas state, more energy needs to be provided to overcome the intermolecular attractive force.
    - ** Solubility **: 1H - Pyrrolo [2,3 - c] pyridine is slightly soluble in water. Water is a polar solvent, and although the nitrogen-containing atoms of this compound can participate in the formation of hydrogen bonds, its conjugated system accounts for a large proportion of hydrophobic hydrocarbons, the overall polarity is limited, and the interaction force with water molecules is weak, so the solubility in water is small. However, it is soluble in common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. These organic solvents can interact with the compound molecules through van der Waals force or π-π stacking, thereby achieving dissolution.
    - ** Density **: The density is about 1.27g/cm ³. The density is related to the molecular structure and relative molecular mass. The molecular structure of the compound is compact and the relative molecular mass is moderate, resulting in its density in this range. < Br > - ** Appearance **: Appearance is often white to light yellow powder or crystalline solid, color is related to purity, high purity is more close to white, the presence of impurities may cause darker color.
    What are the synthesis methods of 1H-Pyrrolo [2,3-c] pyridine
    The synthesis method of 1H-pyrrolido [2,3-c] pyridine is an important research direction in the field of chemistry. There are many synthesis paths, and the common ones are mentioned today.
    First, the target structure is constructed by a multi-step reaction using a nitrogen-containing heterocyclic compound as the starting material. First, a suitable nitrogen heterocyclic ring is taken, and the desired functional group is introduced in an ingenious way under specific reaction conditions. For example, a nucleophilic substitution reaction is used to bind a specific reagent to the nitrogen heterocyclic ring, thereby changing its structure. Subsequently, the cyclization reaction prompts the formation of intracellular rings to construct the basic skeleton of pyrrolido [2,3-c] pyridine. This process requires precise regulation of reaction temperature, time and reagent dosage to obtain higher yield and purity.
    Second, the reaction strategy catalyzed by transition metals can be used. Transition metals have unique catalytic activity, which can accelerate the reaction process and guide the reaction selectivity. Using metals such as palladium and copper as catalysts, with suitable ligands, different substrates are coupled to react. First, the substrate molecules are activated under metal catalysis to enhance their reactivity, and then they are coupled to each other to gradually build the structure of the target compound. Through fine screening of catalysts, ligands and reaction solvents, the reaction conditions can be optimized and the synthesis efficiency can be improved.
    Third, the intramolecular cyclization strategy is adopted. First, linear molecules containing specific functional groups and with appropriate connection methods are prepared. Under specific conditions, such molecules undergo cyclization reactions within the molecule. Acid-base catalysis or photochemical reactions can be used to promote the rearrangement and cyclization of intramolecular chemical bonds, and finally produce 1H-pyrrolido [2,3-c] pyridine. This method requires careful design of the structure of the starting molecule to ensure that the cyclization reaction occurs smoothly and the desired product is generated.
    The above synthesis methods have their own advantages and disadvantages. In practical applications, when considering the availability of raw materials, difficulty of reaction conditions, product purity and yield according to specific needs, the most suitable synthesis path is selected to achieve the purpose of efficient synthesis of 1H-pyrrolido [2,3-c] pyridine.
    Where is 1H-Pyrrolo [2,3-c] pyridine used?
    1H-pyrrolido [2,3-c] pyridine is widely used in various fields. Its unique nature makes it quite versatile.
    In the field of medicine, this compound is often the key raw material for the creation of new drugs. Due to its special structure, it can specifically bind to many biological macromolecules in the body, thereby regulating physiological processes. For example, in the development of anti-tumor drugs, 1H-pyrrolido [2,3-c] pyridine can precisely act on specific targets of cancer cells, inhibit their proliferation and spread, and provide a powerful boost for overcoming cancer problems. And in the development of drugs for nervous system diseases, it can also play an effect, or can regulate the transmission of neurotransmitters and relieve related diseases.
    In the field of materials science, 1H-pyrrolido [2,3-c] pyridine also has outstanding performance. It can participate in the preparation of materials with special photoelectric properties. Materials made on this basis, or in the field of organic Light Emitting Diode (OLED), can improve the luminous efficiency and color purity, and make the image quality of display devices better. In solar cell materials, it can also optimize its photoelectric conversion efficiency and promote the development of renewable energy.
    Furthermore, in the field of pesticides, 1H-pyrrolido [2,3-c] pyridine may become the core component of the creation of new pesticides. With its unique mode of action on the physiological mechanism of pests, it is expected to develop high-efficiency, low-toxicity and environmentally friendly pesticide products, which can not only effectively control pests and diseases, but also reduce the negative impact on the ecological environment.
    In summary, 1H-pyrrolido [2,3-c] pyridine has important application value in many fields such as medicine, materials science, and pesticides, and has made significant contributions to the progress and development of various fields.
    What is the market outlook for 1H-Pyrrolo [2,3-c] pyridine?
    1H-pyrrolido [2,3-c] pyridine, this product has a promising future in today's market and is relevant to various fields.
    Looking at the field of medicine, its future can be described as bright. 1H-pyrrolido [2,3-c] pyridine compounds have made their mark in drug development. Many studies have shown that it has significant affinity and activity for specific disease targets. Taking the development of anti-cancer drugs as an example, researchers have found that such compounds can precisely act on cancer cell proliferation-related proteins and effectively inhibit cancer cell growth. This property makes it an important candidate structure for the research and development of new anti-cancer drugs. Many pharmaceutical companies have included it in the key research and development category. In time, it is expected to lead to new anti-cancer drugs and bring good news to cancer patients.
    In the field of materials science, 1H-pyrrolido [2,3-c] pyridine also has potential applications. Because of its unique molecular structure, it endows materials with special photoelectric properties. Scientists are studying to integrate it into organic optoelectronic materials to improve the luminous efficiency and stability of materials. If the research and development is successful, in the organic Light Emitting Diode (OLED) display technology and other aspects, it may trigger major changes, promote the display technology to a new height, improve the screen image quality and service life, and there is a great demand in the electronic display product market.
    However, its market development also faces challenges. The process of synthesizing 1H-pyrrole [2,3-c] pyridine is currently complex and expensive. As a result, its large-scale production is limited, and the market supply is difficult to meet the surge in demand. Furthermore, although it shows potential in the fields of medicine and materials, some applications are still in the laboratory research stage. To achieve industrialization, many technical problems and regulatory approval hurdles need to be overcome.
    Overall, although 1H-pyrrole [2,3-c] pyridine has broad prospects, it is necessary for scientific researchers and industry to work closely together to break through the bottleneck of the synthesis process and promote technological transformation. Only then can it shine brightly in the market and achieve extraordinary success.